Colloid and Interface Science in Pharmaceutical Research and Development describes the role of colloid and surface chemistry in the pharmaceutical sciences. It gives a detailed account of colloid theory, and explains physicochemical properties of the colloidal-pharmaceutical systems, and the methods for their measurement.
The book starts with fundamentals in Part I, covering fundamental aspects of colloid and interface sciences as applied to pharmaceutical sciences and thus should be suitable for teaching. Parts II and III treat applications and measurements, and they explains the application of these properties and their influence and use for the development of new drugs.
Table of Contents
Part I Fundamentals
Interaction between drugs
Pharmaceutical suspensions
Response of colloidal drugs to external fields
Aggregation of drugs
Concentrated drug particles
Rheology of colloidal suspensions
Part II Applications of Colloid and Interface Science in Pharmaceutical sciences
Liposomes and micelles
Binding of drugs on liposomes
Drug delivery system
Gold nanoparticles
Drug permeation through biological membranes
EPR effects
Part III Measurements
Zeta potential of colloidal drugs
Atomic force microscope
Surface force apparatus
Authors
Hiroyuki Ohshima Professor Emeritus, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Japan.
Hiroyuki Ohshima is Professor Emeritus at the Tokyo University of Science, Japan. He received the B.S. (1968), M.S. (1970), and Ph.D. (1974) degrees in physics from the University of Tokyo. He spent his post-doc study at University of Melbourne, Australia (1981-1983), State University of New York at Buffalo, USA (1983-1984), and University of Utah, USA (1984-1985). He has worked at the Tokyo University of Science, Japan since 1985. He was previously a Professor of Pharmaceutical Sciences at the Tokyo University of Science (1994-2012) and is now a Professor Emeritus and a Visiting Professor. He is the author of Theory of Colloid and Interfacial Electric Phenomena (Elsevier, 2006) and Biophysical Chemistry of Biointerfaces (Wiley, 2010). He edited Electrical Phenomena at Interfaces and Biointerfaces (Wiley, 2012) and Encyclopedia of Biocolloid and Biointerface Science (Wiley, 2016). He co-edited Electrical Phenomena at Interfaces. 2e (Marcel Dekker, 1998) and Colloid and Interface Science in Pharmaceutical Research and Development (Elsevier, 2014). He is also the author or co-author of over 400 book chapters and journal publications, reflecting his research interests in colloid and interface science. He was an Editor of the journal Colloids and Surfaces B: Biointerfaces (1994-2012, Elsevier) and currently he is an Associate Editor of Colloid and Polymer Science (2002-present, Springer). In 2016, Ohshima was awarded the 29th Khwarizmi International Award by the Iranian Research Organization for Science and Technology for his contribution to the theory of colloid and interfacial electric phenomena. In 2017, he was selected as one of Asia's top 100 scientists for 2017 (The Asian Scientist Magazine, June 2017). In 2022, he was awarded Fellow of Japan Oil Chemists' Society. On January 13, 2021, the layman's summary of Ohshima's research article:Gel Electrophoresis of a Soft Particle (Adv. Colloid Interface Sci., 271, 101977, 2019)was published on the Atlas of Science website (https://atlasofscience.org/soft-particle-gel-electrophoresis/).
Kimiko Makino Professor, Faculty of Pharmaceutical Sciences, Tokyo University of Sciences, Noda, Chiba, Japan.
Kimiko Makino is a Professor of Pharmaceutical Sciences at the Tokyo University of Science, Japan. She is the author or co-author of 1 book and over 120 book chapters and journal publications reflecting her research interests in colloid and interface sciences as well as pharmaceutical science. She spent her post-doc life at University of Utah. Dr. Makino received the B.S. (1979), M.S. (1981), and Ph.D. (1986) degrees in pharmaceutical science from Tokyo University of Science. She currently serves as the head of the Center for Physical Pharmaceutics of Tokyo University of Science. She has just been appointed as new Co-Editor in Chief of Journal of Microencapsulation (Informa Healthcare/Taylor & Francis).
