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The Top 100 Drugs. Clinical Pharmacology and Practical Prescribing. Edition No. 3

  • Book

  • November 2022
  • Elsevier Health Science
  • ID: 5597270

Now in its third edition, this small and accessible guide contains essential information for the safe prescribing of the most commonly used drugs in the NHS.

The Top 100 Drugs combines the best elements of a students' textbook with those of a prescribers' manual. It gives equal weight to essential information on the science of pharmacology as well as the real-world practicalities of prescribing, all in an accessible and clear format.

Written by leaders in the field of clinical pharmacology, this popular book has been fully revised and updated to include the drugs used today, including monoclonal antibodies and antiviral drugs for COVID-19. With common indications, mechanism of action, adverse effects, important interactions and a clinical tip for each drug as well as questions to test knowledge, this book is key to helping students understand everything they need to know about the drugs they are likely to use in practice.

  • Compact and easy to follow - can be carried around on the wards

  • Logically ordered - offers multiple ways to find the drug you are looking for

  • A Clinical Tip for each drug, drawn from the authors' experience

  • 100 self-assessment questions to encourage integration and revision of knowledge and understanding
  • Fully updated to include the most commonly prescribed drugs today, based on original research led by the authors of over 1 billion community prescriptions and approximately 1 million hospital prescriptions

  • All drug monographs extensively reviewed and updated

  • Dedicated section emergency drugs

  • Updated self-assessment material, now including calculation and prescription-writing questions, in addition to single-best-answer questions

Table of Contents

List of abbreviations

Introduction

The top 100 drugs listed by system

The top 100 drugs listed by indication

The top 100 drugs (alphabetical listing)

5a-reductase inhibitors

a-blockers

Acetylcholinesterase inhibitors

Acetylcysteine (N-acetylcysteine)

Activated charcoal

Adenosine

Adrenaline (epinephrine)

Aldosterone antagonists

Alginates and antacids

Allopurinol

Aminoglycosides

Aminosalicylates

Amiodarone

Angiotensin-converting enzyme (ACE) inhibitors

Angiotensin receptor blockers

Antidepressants, selective serotonin reuptake inhibitors

Antidepressants, tricyclics and related drugs

Antidepressants, venlafaxine and mirtazapine

Antiemetics, dopamine D2-receptor antagonists

Antiemetics, histamine H1-receptor antagonists

Antiemetics, serotonin 5-HT3-receptor antagonists

Antifungal drugs

Antihistamines (H1-receptor antagonists)

Antimotility drugs

Antimuscarinics, bronchodilators

Antimuscarinics, cardiovascular and gastrointestinal uses

Antimuscarinics, genitourinary uses

Antipsychotics, first-generation (typical)

Antipsychotics, second-generation (atypical)

Antiviral drugs

Antiplatelet drugs, ADP-receptor antagonists

Antiplatelet drugs, aspirin

Azathioprine

?-blockers

?2-agonists

Benzodiazepines

Bisphosphonates

Calcium and vitamin D

Calcium channel blockers

Carbamazepine

Cephalosporins and carbapenems

Chloramphenicol

Corticosteroids (glucocorticoids), inhaled

Corticosteroids (glucocorticoids), systemic

Corticosteroids (glucocorticoids), topical

Digoxin

Dipeptidylpeptidase-4 inhibitors

Direct oral anticoagulants

Diuretics, loop

Diuretics, thiazide and thiazide-like

Dopaminergic drugs for Parkinson's disease

Emollients

Fibrinolytic drugs

Gabapentin and pregabalin

H2-receptor antagonists

Heparins and fondaparinux

Insulin

Iron

Lamotrigine

Laxatives, osmotic

Laxatives, stimulant

Leukotriene receptor antagonists

Levetiracetam

Lidocaine

Macrolides

Metformin

Methotrexate

Metronidazole

Naloxone

Nicotine replacement and related drugs

Nitrates

Nitrofurantoin

Non-steroidal antiinflammatory drugs

Ocular lubricants (artificial tears)

Oestrogens and progestogens

Opioids, strong

Opioids, weak/moderate

Oxygen

Paracetamol

Penicillins

Penicillins, antipseudomonal

Penicillins, broad-spectrum

Penicillins, penicillinase-resistant

Phosphodiesterase (type 5) inhibitors

Prostaglandin analogue eye drops

Proton pump inhibitors

Quinine

Quinolones

Serotonin 5-HT1-receptor agonists

Sex hormone antagonists for breast cancer

Statins

Sulphonylureas

Tetracyclines

Thyroid hormones

Trimethoprim

Valproate (valproic acid)

Vancomycin

Vitamins

Warfarin

Z-drugs

Fluids

Colloids (plasma substitutes)

Compound sodium lactate (Hartmann's solution)

Glucose (dextrose)

Potassium chloride

Sodium chloride

Self-assessment and knowledge integration

100 single best-answer questions

Answers and explanations

Index

Authors

Andrew W. Hitchings Reader in Clinical Pharmacology, St George's, University of London, Honorary Consultant in Neurointensive Care, St George's University Hospitals NHS Foundation Trust, London.

Dagan Lonsdale Honorary Senior Lecturer, St George's, University of London; Specialty Registrar in Clinical Pharmacology, General Medicine and Intensive Care Medicine, St George's University Hospitals NHS Foundation Trust, London, UK.

Dagan Lonsdale, BSc(Hons) MBBS MRCP FHEA, Honorary Senior Lecturer, St George's, University of London; Specialty Registrar in Clinical Pharmacology, General Medicine and Intensive Care Medicine, St George's University Hospitals NHS Foundation Trust, London, UK
Daniel Burrage NIHR Doctoral Research Fellow, St George's, University of London; Specialty Registrar in Clinical Pharmacology, General Medicine and Stroke Medicine, St George's University Hospitals NHS Foundation Trust, London, UK.

Daniel Burrage, BSc(Hons) MBBS MSc (Med Ed) MRCP FHEA , NIHR Doctoral Research Fellow, St George's, University of London; Specialty Registrar in Clinical Pharmacology, General Medicine and Stroke Medicine, St George's University Hospitals NHS Foundation Trust, London, UK
Emma Baker Professor of Clinical Pharmacology, St George's University of London; Honorary Consultant Physician, St George's University Hospitals NHS Foundation Trust, London, UK..

Professor Emma Baker (PhD FRCP) is a clinical academic with roles in research, teaching and clinical medicine. At St George's, University of London she is the head of the Clinical Pharmacology Unit, lead for prescribing education and assessment and chair of the Drugs and Therapeutics Committee. Current external roles include respiratory specialty group lead, (London South Comprehensive Local Research Network) and executive editor of the British Journal of Clinical Pharmacology.

In research, she gained her PhD from Manchester University in 1996. She subsequently moved to St George's and developed a research programme in epithelial transport and respiratory infection, with external funding from bodies including the Wellcome Trust and Medical Research Council. Her research has developed from early work in molecular biology to development and implementation of investigator-led clinical trials.

In teaching, she was awarded a National Teaching Fellowship of the Higher Education Academy in 2003 and has received a St George's undergraduate teaching prize in eight different years. She has co-authored a respiratory text book (Case-based respiratory medicine) and is currently leading her clinical pharmacology trainees in writing two new prescribing textbooks for publication in 2014.

In clinical practice, she has a specialist interest in chronic obstructive pulmonary disease and runs an outpatient service for patients with airways disease. She shares the inpatient care of respiratory patients with four colleagues and is on the on call rota for acute medical intaking.