+353-1-416-8900REST OF WORLD
+44-20-3973-8888REST OF WORLD
1-917-300-0470EAST COAST U.S
1-800-526-8630U.S. (TOLL FREE)

Modeling Neuropsychiatric Disorders in Laboratory Animals

  • Book

  • September 2015
  • Elsevier Science and Technology
  • ID: 3329012
Modeling Neuropsychiatric Disorders in Laboratory Animals serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals interested in the use of animal models in preclinical research related to human neuropsychiatric disorders.

The text focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders. Chapters contain discussions on both classical and modern views on the validation of animal models for neuropsychiatric disorders, also discussing the utility of endophenotypes in modeling neuropsychiatric disease.

Subsequent chapters deal with four specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders. Final sections discuss the future for the development, validation, and use of animal models in basic and preclinical research.

Please Note: This is an On Demand product, delivery may take up to 11 working days after payment has been received.

Table of Contents

  • Chapter 1: What is an animal model, and how is it validated?
  • Chapter 2: Depressive Disorders
  • Chapter 3: Anxiety Disorders
  • Chapter 4: Obsessive-compulsive and related disorders
  • Chapter 5: Synthesis and Future Directions

Authors

Kurt Leroy Hoffman Investigator, Dr. Carlos Beyer Flores Center, Tlaxcala, Mexico and Professor, Postgraduate Program in Biological Sciences, Autonomous University of Tlaxcala, Mexico.. Dr. Hoffman has studied neurobiological processes in a variety of model animals ranging from Manduca sexta (the common tobacco hawkmoth) to the European rabbit. He received a Bachelor of Science degree in Zoology from the University of Wisconsin, Madison, and a doctoral degree in Biology from the Institute of Neuroscience at the University of Oregon, Eugene. His research has involved diverse aspects of neurobiology and behavior, including neuronal differentiation and myelination, neuroendocrinology and programmed cell death, reproductive behavior, and animal models for studying obsessive-compulsive disorder and schizophrenia. Currently, his work focuses on the neurobiological underpinnings of animal behavior - both normal and abnormal - in order to gain a better understanding of the neurobiology of human mental illness.