Stem Cells and Cancer in Hepatology. From the Essentials to Application

Authors

Yun-Wen Zheng Associate Professor, Department of Advanced Gastroenterological Surgical Science and Technology, Faculty of Medicine, University of Tsukuba, Japan and Visiting Associate Professor, Department of Regenerative Medicine, School of Medicine, Yokohama City University, Japan and Distinguished Medical Expert and Visiting Professor, Research Center of Stem Cells and Regenerative Medicine, Jiangsu University Hospital, China. As a stem cell biologist, Dr. Zheng earned his PhD of Medical Science majoring in Physiology/Stem Cell Biology in the University of Tsukuba Graduate School of Medicine, Japan in 2003. From 2003 to present, he has been a team leader for liver and cancer stem cell researches. Dr. Zheng is interested in the identification and isolation of endoderm stem cells as well as liver stem cells in normal and cancer tissues from rodents and human sources; especially for hepatic primordial development and the microenvironment, and drug development, he is trying to generate chimera mouse and rat with humanized livers. Furthermore, for clinical application, he is investigating how to generate the hepatic organoids with cell-cell interactions from the same patient with somatic stem cells from the amnion tissue, umbilical cord and the same source iPS cells. He is also interested in understanding cellular reprogramming and trying cellular therapies, to converse one cell directly into another type in vitro and in vivo.