Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

Table of Contents

1. Current status and future challenges of various polymers as cancer therapeutics 2. An overview of polymeric nanoparticles as potential cancer therapeutics 3. Poly acrylate (e.g., poly methylacrylate, poly ethyl acrylate, etc.) nanoparticles as promising tool for anticancer therapeutics 4. Poly (alkyl cyano acrylate) nanoparticles as promising tool for anticancer therapeutics 5. Poly (a-hydroxy acids) based nanoparticles for Drug/Gene delivery for cancer therapy 6. Poly (ester), Poly hydroxy alkanoate nanoparticles as promising tool for anticancer therapeutics 7. Poly (phospho ester), Poly (phosphazene) nanoparticles as promising tool for anticancer therapeutics 8. Poly (carbonate) nanoparticles as promising tool for anticancer therapeutics 9. Poly (amino acid) nanoparticles as promising tool for anticancer therapeutics 10. Poly ethylene glycol nanoparticles as promising tool for anticancer therapeutics 11. Dendrimer (polyamidoamine, polypropylene imine, poly-L-lysine, carbosilane dendrimers, triazine dendrimers) as promising tool for anticancer therapeutics 12. Conjugated polymer nanoparticles as promising tool for anticancer therapeutics 13. Microbes based natural polymer (Xanthum gum, alginate, gellan gum, carrageenan) nanoparticles as promising tool for anticancer therapeutics 14. Plant based natural polymer (Guar gum, pectin, starch, cellulose, cyclodextrins) nanoparticles as promising tool for anticancer therapeutics 15. Animal based natural polymer (Gelatin, chitosan, albumin, hyaluronic acid, chondroitin sulphate) nanoparticles as promising tool for anticancer therapeutics 16. Polymersomes as promising tool for anticancer therapeutics 17. Other polymers (Poly sulfonic acids, Poly carboxylic acids, Poly boronic acid, Poly silamine, etc.) nanoparticles as promising tool for anticancer therapeutics 18. Conclusion and future prospective of polymeric nanoparticles as cancer therapeutics

Authors

Prashant Kesharwani Assistant Professor, School of Pharmaceutical Education and Research, Jamia Hamdard University, New Delhi, India. Dr. Prashant Kesharwani is presently working as an assistant professor at Department of Pharmaceutics, Jamia Hamdard, New Delhi, India. He is also a receipt of SERB-Ramanujan fellowship (the most prestigious fellowship) from India. Dr. Kesharwani have academic, industrial and research experience at international level (including USA, Malaysia and India). An overarching goal of his current research is the development of nano-engineered drug delivery systems for various diseases. Dr. Kesharwani has more than 300 international publications in well reputed journals and 22 published books (Elsevier). His h-index is 63 and i-10 index is 230 (on April 2023). He is a recipient of several internationally acclaimed awards and research funding from various funding bodies. He has presented many invited talks and oral presentations at prestigious scientific peer-conferences, received international acclaims and awards for research contribution, supervised students/junior researchers and actively participated in outreach and scientific dissemination for the service of wider community. Kishore M. Paknikar Professor Agharkar Chair, Agharkar Research Institute, Pune, India
Visiting Professor, Indian Institute of Technology Bombay, Mumbai, India
Visiting Professor, Malaviya National Institute of Technology, Jaipur, India. Dr. Kishore M. Paknikar is Professor Agharkar Chair and former Director of Agharkar Research Institute, Pune, India. He is a MSc in Microbiology (1980) and a PhD in Microbiology (1984) from the University of Poona, India. His work in the field of delivery systems focuses on the delivery of drugs, proteins, peptides, siRNA, and nutrients. He is also exploring systems like polymeric nanoparticles and dendrimers for delivery of bioactive molecules in the treatment of cancers, Alzheimer's disease, candidiasis, etc. He has more than 120 publications in highly reputed journals and 33 patents to his credit. He was a visiting Professor at Louis Pasteur University (Strasbourg, France) and Wayne State University (School of Medicine, Detroit, USA). He also worked as a Research Advisor at National Nanotechnology Centre (Ministry of Science and Technology), Bangkok, Thailand. He has several fellowships and awards to his credit. Virendra Gajbhiye Scientist in Nanomedicine, Agharkar Research Institute, Pune, India. Dr. Virendra Gajbhiye has been working in the field of nanomedicine for the last 15 years. He has a doctoral degree (Ph.D.) in Pharmaceutical Science with post-doctoral research experience at University of Wisconsin-Madison and Oregon Health and Sciences University. Since 2013 he is working as a Scientist in Nanomedicine at Agharkar Research Institute, Pune, India. He has worked extensively with polymeric nanoparticles specially dendrimers and mesoporous silica nanoparticles. His research interest lies in Nanomedicine, Targeted drug and siRNA delivery, Biomedical application of dendrimers, Biomaterials unimolecular micelles and imaging, Multifunctional polymeric nanoparticles, Nanoparticles in tissue engineering.