Structural Biology and Molecular Modeling Techniques Market - Growth, Trends, COVID-19 Impact, and Forecasts (2023-2028)

The structural biology and molecular modeling techniques market is anticipated to register a CAGR of nearly 10.4% during the forecast period.

COVID-19 had a significant impact on the growth of the market. This was mainly due to the rising demand for the development of appropriate vaccination by understanding the molecular biology of SARS-CoV-2. For instance, the Nature Journal article published in January 2022 mentioned that structural biology can be used to study the pathogenic mechanism of viruses but also provides theoretical information for drug development and optimization. Such advantages provided by structural biology and molecular techniques are expected to drive the market's growth during the forecast period. Thus, COVID-19 had a profound impact on the growth of the market during the pandemic period. In addition, the demand for structural biology is expected to remain intact due to the emergence of a mutant strain of the SARS-CoV-2 virus and the increasing need for understanding the functioning of these mutant virus structures to develop appropriate treatments, thereby boosting the growth of the market over the forecast period.

Certain factors driving the market growth include technological innovations and advancements and the rising prevalence of chronic diseases. For instance, the British Heart Foundation (BHF) data published in January 2022 reported that in 2021, the most common heart conditions affected globally were coronary (ischemic) heart disease (global prevalence estimated at 200 million), peripheral arterial (vascular) disease (110 million), stroke (100 million) and atrial fibrillation (60 million). The report also mentioned that the prevalence of heart and circulatory diseases in North America was 46 million, in Europe 99 million, in Africa 58 million, in South America 32 million, in Asia and Australia 310 million. Additionally, according to the December 2021 report of the International Diabetes Federation (IDF), about 537 million adults of age 20-79 years were living with diabetes in 2021, and more than 90% of this population have Type 2 diabetes. As per the same source, the incidence of diabetes is expected to reach 643 million by 2030 and 783 million by 2040, and low- and middle-income countries were most affected by it. Also, it was estimated that about 541 million adults were at increased risk of developing Type 2 diabetes. Thus, the incidence of various chronic diseases is expected to drive the demand for structural biology and molecular modeling techniques to understand disease prevalence and develop appropriate treatments, thereby driving the market's growth over the forecast period.

Moreover, the increasing product launches by major market players to meet the growing demand for advanced structural biology and molecular modeling techniques contribute to the growth o the market. For instance, in July 2021, the London-based company Deep Mind released an open version source of its deep-learning neural network Alphafold2 and described its approach. It is software that accurately determines the 3D shape of proteins and is set to become widely available to scientists. Similarly, in January 2021, ComputaBio launched molecular dynamics simulation services for industrial and academic clients to better their capability for drug design and expedite drug development programs. Such launches of innovative software for drug development and the availability of molecular data are expected to drive the market's growth.

Thus the above-mentioned factors, such as the rising prevalence of chronic diseases and increasing launches of technologically advanced products, are expected to boost the market's growth during the forecast period. However, the lack of skilled professionals is expected to limit the market's growth during the forecast period.

Structural Biology & Molecular Modeling Techniques Market Trends

Drug Development is Expected to Hold Significant Market Share Over the Forecast Period

The propelling factors for the growth of the drug discovery market include the rising prevalence of a wide range of chronic diseases (such as cardiovascular and CNS-related disorders), rising healthcare expenditure, and the upcoming patent expiration of blockbuster drugs. For instance, the MDPI Journal research article published in September 2021 reported that the prevalence of Peripheral Arterial Disease (PAD) is estimated to be 3-12%, affecting nearly 27 million people in America and Europe in 2021. The same source also reported that in Europe, the prevalence of PAD is estimated at around 17.8% between the ages of 45 and 55 in 2021. Similarly, according to the WHO data published in February 2022, about 50 million people with epilepsy are living worldwide in 2022. The report also mentioned that approximately 80% of the population with epilepsy reside in low- and middle-income countries in 2022. Such a high frequency of various chronic diseases among the population is also expected to drive the demand for advanced drug development procedures, thereby contributing to the growth of the studied segment over the forecast period. Also, innovative product launches for drug discovery are expected to drive the growth of the studied segment. For instance, in July 2022, CD Biosciences launched a series of structural characterization services for kinase/phosphate research and drug development.

Thus, the increasing prevalence of a diverse range of diseases among all age groups and its burden globally drives the demand for drug discovery and its market. There has been an upsurge in the usage of advanced technologies, such as high throughput, bioinformatics, and combinatorial chemistry, for better drug candidate identification.

North America is Expected to Hold a Significant Share in the Market Over the Forecast Period

North America is expected to hold a significant share due to various ongoing research in biological sciences, considerable investments by various biotechnology companies, and the consistently increasing utilization of structural biology and molecular modeling techniques in the market.

Additionally, the rising prevalence of various chronic diseases and increasing demand for advanced modeling techniques to study the prevalence of the disease for the development of appropriate treatments are expected to play a crucial role in the market's growth. For instance, the Cancer Facts and Figures data published by the American Cancer Society in January 2022, there will be an estimated 1.9 million new cancer cases diagnosed in the United States in 2022. Similarly, as per the Heart Disease and Stroke Statistics, Fact Sheet published in May 2022, approximately every 40 seconds, a person in the United States is anticipated to have a myocardial infarction. Likewise, the CDC data updated in September 2021 reported that approximately 6.5 million people aged 40 and older in the United States have peripheral arterial disease. Additionally, as per the Heart and Stroke Foundation of Canada, in February 2022, 750,000 people are living with heart failure, and 100,000 people are diagnosed with heart failure each year in the country. Hence, the prevalence of chronic diseases coupled with the increasing geriatric population in the country is anticipated to create more opportunities for the development of new molecular modeling techniques for the drug discovery and development process.

Additionally, the launch of advanced structural biology and Molecular Modeling Technologies in the United States is expected to drive the growth of the studied market. In April 2021, the Accelra company released a new version of ACEMD, Accela's molecular dynamics simulation software. This is useful as a tool for ligand and system preparation and small molecule parameterization.

Thus, due to the prevalence of chronic diseases giving rise to the demand for advanced drug discovery techniques, the studied market is expected to grow during the forecast period in this region.

Structural Biology & Molecular Modeling Techniques Market Competitor Analysis

The Structural Biology and Molecular Modeling Techniques Market is competitive and consists of a number of major players. Companies like Acellera Ltd, Agile Molecule, Agilent Technologies Inc., Biomax Informatics AG, Bruker Daltonics Inc., Chemical Computing Group, Dassault Systèmes, Illumina, and ThermoFisher Scientific, hold a substantial market share in the market.

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