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Schizophrenia - Epidemiology Forecast - 2034

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    Report

  • 198 Pages
  • December 2024
  • Region: Global
  • DelveInsight
  • ID: 5174529
UP TO OFF until Dec 31st 2024
The ‘Schizophrenia - Epidemiology Forecast - 2034’ report delivers an in-depth understanding of schizophrenia, historical and forecasted epidemiology, as well as the trends in the United States, EU4 (Germany, France, Italy, and Spain), and the United Kingdom, and Japan.

Schizophrenia Understanding

Schizophrenia is a complex and chronic mental disorder characterized by a range of symptoms including hallucinations, delusions, disorganized thinking, and impaired social functioning people globally. Onset typically occurs in late teens to early 20s for men and late 20s to early 30s for women.

Schizophrenia symptoms vary but typically fall into three categories: psychotic (e.g., hallucinations and delusions), negative (e.g., loss of motivation and social withdrawal), and cognitive (e.g., attention and memory problems). Hallucinations involve perceiving things that are not real, such as hearing voices. Delusions are strong, false beliefs. Negative symptoms include loss of motivation and social withdrawal, while cognitive symptoms affect attention and memory, making daily functioning challenging.

The exact cause of schizophrenia remains unclear, but it is believed to result from a combination of genetic, environmental, and neurobiological factors. Abnormalities in brain structure and neurotransmitter systems, particularly dopamine, glutamate, and serotonin, may contribute to the development of this disorder.

Schizophrenia Diagnosis

Diagnosis of schizophrenia involves ruling out other conditions and may include physical exams, blood tests, and psychiatric evaluations. Tools like the Schizophrenia Symptoms Diagnosis Scale (PANSS, CGI, SANS) may also be utilized to assess symptoms and severity.
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Schizophrenia Epidemiology Perspective

The disease epidemiology covered in the report provides historical as well as forecasted epidemiology segmented by total prevalent cases of schizophrenia, total diagnosed prevalent cases of schizophrenia, gender-specific diagnosed prevalent cases of schizophrenia, and severity-specific diagnosed prevalent cases of schizophrenia in the 7MM covering the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan from 2020 to 2034.

Schizophrenia Detailed Epidemiology Segmentation

  • According to estimates, the total diagnosed prevalent cases of schizophrenia in the 7MM were approximately 3,796,850 in 2022. These cases are expected to increase during the study period (2020-2034).
  • In 2022, the US accounted for the highest cases of diagnosed prevalent cases of schizophrenia among the 7MM, with nearly 1,412,470 cases, expected to increase by 2034.
  • Among EU4 and the UK, Germany had the highest diagnosed population of schizophrenia, with approximately 452,772 cases, followed by the UK with approximately 386,344 cases. On the other hand, Spain had the lowest number of diagnosed schizophrenia cases in the region in 2022.
  • Japan accounted for around 795,563 diagnosed prevalent cases of schizophrenia in 2022. These cases are expected to decrease during the forecast period.
  • The gender-specific cases of schizophrenia in the US were nearly 655,002 for females and 757,469 for males in 2022 and are expected to increase within the forecast period (2023-2034).
  • Among EU4 and the UK, prevalence of diagnosed cases of schizophrenia varies according to severity, with the highest prevalence observed in severe schizophrenia with around 630,955 cases, followed by moderate type with 583,405 cases, and mild with 374,455 cases in 2022. These cases are expected to change during the forecast period (2023-2034).
  • In Japan, the severity-specific diagnosed prevalent cases of schizophrenia in 2022 revealed varying levels of symptom severity, with nearly 450,712 cases classified as mild, 173,599 as moderate, and 171,253 as severe in 2022.

Scope of the Report

  • The report covers a descriptive overview of schizophrenia, explaining its symptoms, pathophysiology, and various diagnostic approaches.
  • The report provides insight into the 7MM historical and forecasted patient pool covering the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.
  • The report assesses the disease risk and burden of schizophrenia.
  • The report helps recognize the growth opportunities in the 7MM concerning the patient population.
  • The report provides the segmentation of the disease epidemiology for the 7MM, by total prevalent cases of schizophrenia, total diagnosed prevalent cases of schizophrenia, gender-specific diagnosed prevalent cases of schizophrenia and severity-specific diagnosed prevalent cases of schizophrenia.

Report Highlights

  • Twelve years forecast of schizophrenia
  • The 7MM Coverage
  • Total Prevalent Cases of Schizophrenia
  • Total Diagnosed Prevalent Cases of Schizophrenia
  • Gender-specific Diagnosed Prevalent Cases of Schizophrenia
  • Severity-specific Diagnosed Prevalent Cases of Schizophrenia

Key Questions Answered

  • What are the disease risks and burdens of schizophrenia?
  • What is the historical schizophrenia patient pool in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan?
  • What would be the forecasted patient pool of schizophrenia at the 7MM level?
  • What growth opportunities will be across the 7MM concerning the patient population with schizophrenia?
  • Which country would have the highest diagnosed prevalent population of schizophrenia among the countries mentioned above during the forecast period (2023-2034)?
  • At what CAGR is the population expected to grow across the 7MM forecast period (2023-2034)?

Reasons to Buy

The schizophrenia report will allow the user to:

  • Develop business strategies by understanding the trends shaping and driving the 7MM schizophrenia epidemiology forecast.
  • The schizophrenia epidemiology report and model were written and developed by Masters and PhD level epidemiologists.
  • The schizophrenia epidemiology Model is easy to navigate, interactive with a dashboard, and epidemiology based on transparent and consistent methodologies. Moreover, the model supports the data presented in the report and showcases disease trends over the 12-year forecast period using reputable sources.

Key Assessments

  • Patient Segmentation
  • Disease Risk and Burden
  • Risk of Disease by Segmentation
  • Factors Driving Growth in a Specific Patient Population

Geographies Covered

  • The United States
  • EU4 (Germany, France, Italy, and Spain) and the United Kingdom
  • Japan

Study Period: 2020-2034

Table of Contents

1. Key Insights2. Report Introduction
3. Schizophrenia Epidemiology Overview at a Glance
3.1. Patient Share (%) Distribution of Schizophrenia in 2020
3.2. Patient Share (%) Distribution of Schizophrenia in 2034
4. Methodology of Schizophrenia Epidemiology5. Executive Summary of Schizophrenia
6. Disease Background and Overview
6.1. Introduction of Schizophrenia
6.2. Signs and Symptoms of Schizophrenia
6.3. Risk Factors
6.4. Subtypes of Schizophrenia
6.5. Pathophysiology
6.5.1. Genetics of Schizophrenia
6.6. Biomarkers in Schizophrenia
6.7. Diagnosis
6.7.1. Symptoms Rating Scales in Schizophrenia
6.7.2. Algorithm for Differential Diagnosis of Negative Symptoms
6.7.3. Differential Diagnosis
7. Patient Journey
8. Epidemiology and Patient Population
8.1. Key Findings
8.2. Assumptions and Rationale
8.2.1. Total Prevalent Cases of Schizophrenia
8.2.2. Total Diagnosed Prevalent Cases of Schizophrenia
8.2.3. Gender-specific Diagnosed Prevalent Cases of Schizophrenia
8.2.4. Severity-specific Diagnosed Prevalent Cases of Schizophrenia
8.3. Total Prevalent Cases of Schizophrenia in the 7MM
8.4. Total Diagnosed Prevalent Cases of Schizophrenia in the 7MM
8.5. The US
8.5.1. Total Prevalent Cases of Schizophrenia in the US
8.5.2. Total Diagnosed Prevalent Cases of Schizophrenia in the US
8.5.3. Gender-specific Diagnosed Prevalent Cases of Schizophrenia in the US
8.5.4. Severity-specific Diagnosed Prevalent Cases of Schizophrenia in the US
8.6. EU4 and the UK
8.6.1. Total Prevalent Cases of Schizophrenia in EU4 and the UK
8.6.2. Total Diagnosed Prevalent Cases of Schizophrenia in EU4 and the UK
8.6.3. Gender-specific Diagnosed Prevalent Cases of Schizophrenia in EU4 and the UK
8.6.4. Severity-specific Diagnosed Prevalent Cases of Schizophrenia in EU4 and the UK
8.7. Japan
8.7.1. Total Prevalent Cases of Schizophrenia in Japan
8.7.2. Total Diagnosed Prevalent Cases of Schizophrenia in Japan
8.7.3. Gender-specific Diagnosed Prevalent Cases of Schizophrenia in Japan
8.7.4. Severity-specific Diagnosed Prevalent Cases of Schizophrenia in the US
9. KOL Views10. Unmet Needs
11. Appendix
11.1. Bibliography
11.2. Acronyms and Abbreviations
12.3. Report Methodology
12. Publisher Capabilities13. Disclaimer14. About the Publisher
List of Tables
Table 1: Summary of Epidemiology (2020-2034)
Table 2: Early Symptoms of Schizophrenia
Table 3: Symptoms of Schizophrenia
Table 4: Clinical Features of Schizophrenia, Schizoaffective Disorder
Table 5: Total Prevalent Cases of Schizophrenia in the 7MM (2020-2034)
Table 6: Total Diagnosed Prevalent Cases of Schizophrenia in the 7MM (2020-2034)
Table 7: Total Prevalent Cases of Schizophrenia in the US (2020-2034)
Table 8: Total Diagnosed Prevalent Cases of Schizophrenia in the US (2020-2034)
Table 9: Gender-specific Diagnosed Prevalent Cases of Schizophrenia in the US (2020-2034)
Table 10: Severity-specific Diagnosed Prevalent Cases of Schizophrenia in the US (2020-2034)
Table 11: Total Prevalent Cases of Schizophrenia in EU4 and the UK (2020-2034)
Table 12: Total Diagnosed Prevalent Cases of Schizophrenia in EU4 and the UK (2020-2034)
Table 13: Gender-specific Diagnosed Prevalent Cases of Schizophrenia in EU4 and the UK (2020-2034)
Table 14: Severity-specific Diagnosed Prevalent Cases of Schizophrenia in EU4 and the UK (2020-2034)
Table 15: Total Prevalent Cases of Schizophrenia in Japan (2020-2034)
Table 16: Total Diagnosed Prevalent Cases of Schizophrenia in Japan (2020-2034)
Table 17: Gender-specific Diagnosed Prevalent Cases of Schizophrenia in Japan (2020-2034)
Table 18: Severity-specific Diagnosed Prevalent Cases of Schizophrenia in Japan (2020-2034)
List of Figures
Figure 1: Early Symptoms of Schizophrenia
Figure 2: Interaction of Genetic and Environmental Risk Factors in the Developmental Pathology of Schizophrenia
Figure 3: Causes and Risk Factors of Schizophrenia
Figure 4: Neuron-glia Interactions in the Cerebral Cortex - Key Neural Substrates for the Pathology of Schizophrenia
Figure 5: Schematic Representation of Drug Actions that Normalize Aberrant Glutamate Neurotransmission in the Prefrontal Cortex of Schizophrenics
Figure 6: Hypothesis of Schizophrenia
Figure 7: A Representative Molecular Pathway for Schizophrenia - Fine Tuning of the Glutamate Synapse
Figure 8: Differential Diagnosis of Negative Symptoms
Figure 9: Patient Journey
Figure 10: Total Prevalent Cases of Schizophrenia in the 7MM (2020-2034)
Figure 11: Total Diagnosed Prevalent Cases of Schizophrenia in the 7MM (2020-2034)
Figure 12: Total Prevalent Cases of Schizophrenia in the US (2020-2034)
Figure 13: Total Diagnosed Prevalent Cases of Schizophrenia in the US (2020-2034)
Figure 14: Gender-specific Diagnosed Prevalent Cases of Schizophrenia in the US (2020-2034)
Figure 15: Severity-specific Diagnosed Prevalent Cases of Schizophrenia in the US (2020-2034)
Figure 16: Total Prevalent Cases of Schizophrenia in EU4 and the UK (2020-2034)
Figure 17: Total Diagnosed Prevalent Cases of Schizophrenia in EU4 and the UK (2020-2034)
Figure 18: Gender-specific Diagnosed Prevalent Cases of Schizophrenia in EU4 and the UK (2020-2034)
Figure 19: Severity-specific Diagnosed Prevalent Cases of Schizophrenia in EU4 and the UK (2020-2034)
Figure 20: Total Prevalent Cases of Schizophrenia in Japan (2020-2034)
Figure 21: Total Diagnosed Prevalent Cases of Schizophrenia in Japan (2020-2034)
Figure 22: Gender-specific Diagnosed Prevalent Cases of Schizophrenia in Japan (2020-2034)
Figure 23: Severity-specific Diagnosed Prevalent Cases of Schizophrenia in Japan (2020-2034)
Figure 24: Unmet Needs