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Schizophrenia: Seven-Market Drug Forecast and Market Analysis - Update

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    Report

  • 144 Pages
  • December 2024
  • Region: Global
  • GlobalData
  • ID: 6034123
This report covers the 7MM (US, France, Germany, Italy, Spain, UK, Japan) and provides an Excel-based forecast model for the schizophrenia market through 2031.

The analyst forecasts that the global schizophrenia marketplace-which, for the purposes of this report, comprises seven major pharmaceutical markets (7MM) (US, France, Germany, Italy, Spain, UK, and Japan)-to experience steady growth during the forecast period. This growth will be driven primarily by the launch of five adjunctive therapies that are designed to be used in combination with the other marketed antipsychotics. These include Neurocrine Biosciences’ Ingrezza (valbenazine) and NBI-1117568, Bristol Myers Squibb’s Cobenfy (trospium chloride + xanomeline), and Boehringer Ingelheim’s Iclepertin/BI-425809. Although the majority of the therapies that are already in the market are genericized, patent expiries of long-acting injectable (LAI) atypical antipsychotics such as Abilify Maintena and Aristada are expected to curtail market growth.

This model covers the market forecast for schizophrenia marketed therapies and late-stage pipeline candidates. The base year of this model is 2021 and the forecast period is 2021-31.

Scope

  • Overview of Schizophrenia, including epidemiology, symptoms, diagnosis, and disease management.
  • Annualized schizophrenia therapeutics market revenue, cost of therapy per patient, and treatment usage patterns forecast from 2021 to 2031.
  • Key topics covered include strategic competitor assessment, market characterization, unmet needs, clinical trial mapping, and implications of these factors for the schizophrenia therapeutics market.
  • Pipeline analysis: comprehensive data assessing emerging trends and mechanisms of action under development for schizophrenia treatment. The most promising candidates in late-stage development are profiled.
  • Analysis of the current and future market competition in the global schizophrenia therapeutics market. Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications.

Reasons to Buy

  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
  • Develop business strategies by understanding the trends shaping and driving the 7MM schizophrenia therapeutics market.
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the 7MM schizophrenia therapeutics market in the future.
  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.

Table of Contents

  • About the Analyst
1 Schizophrenia: Executive Summary - Updated November 2024, Based on Events up to November 22
1.1 The schizophrenia market will grow to $17.0 billion.
1.2 Key players will struggle to maintain their competitive position.
1.3 While outlook for schizophrenia management made headway, opportunities remain to improve patient outcomes.
1.4 The entry of adjunctive therapies will shape the schizophrenia market.
1.5 What do physicians think?
2 Introduction - Updated November 2024
2.1 Catalyst
2.2 Related Reports
2.3 Upcoming Reports
3 Disease Overview
3.1 Etiology and Pathophysiology
3.1.1 Etiology
3.1.2 Pathophysiology
3.2 Classification or Staging Systems
4 Epidemiology
4.1 Disease background
4.2 Risk factors and comorbidities.
4.3 Global and historical trends
4.4 7MM forecast methodology.
4.4.1 Sources used.
4.4.2 Forecast assumptions and methods.
4.4.3 Forecast assumptions and methods: 12-month total prevalent cases of schizophrenia.
4.5 Epidemiological Forecast for Schizophrenia (2021-31)
4.5.1 12-Month total prevalent cases of schizophrenia
4.5.2 12-Month diagnosed prevalent cases of schizophrenia
4.5.3 Age-specific 12-month diagnosed prevalent cases of schizophrenia.
4.5.4 Sex-specific 12-month diagnosed prevalent cases of schizophrenia.
4.6 Discussion
4.6.1 Epidemiological forecast insight
4.6.2 COVID-19 Impact
4.6.3 Limitations of Analysis
4.6.4 Strengths of Analysis
5 Disease Management - Updated November 2024, Based on Events up to November 22
5.1 Diagnosis overview
5.2 Treatment overview
5.3 Non-pharmacological management of schizophrenia
6 Competitive Assessment - Updated November 2024, Based on Events up to November 22
6.1 Overview
7 Unmet Needs and Opportunity Assessment - Updated November 2024, Based on Events up to November 22
7.1 Overview
7.2 Development of therapies to target cognitive impairment associated with schizophrenia
7.3 Development of therapies to target negative symptoms.
7.4 Development of therapies for treatment-resistant patients
7.5 Improved patient insight and adherence to treatment
8 R&D Strategies - Updated November 2024, Based on Events up to November 22
8.1 Overview
8.1.1 Reformulations and innovative drug delivery systems
8.1.2 Novel MOAs
8.1.3 Development of adjunctive therapies
8.1.4 Digital therapeutics
8.2 Clinical trial design
8.2.1 Clinical endpoints
8.2.2 Patient Recruitment
9 Pipeline Assessment - Updated November 2024, Based on Events up to November 22
9.1 Overview
9.2 Promising Drugs in Clinical Development
10 Pipeline Valuation Analysis - Updated November 2024, Based on Events up to November 22
10.1 Overview
10.2 Competitive Assessment
11 Current and Future Players - Updated November 2024, Based on Events up to November 22
11.1 Overview
11.2 Deal-making trends
12 Market Outlook - Updated November 2024, Based on Events up to November 22
12.1 Global Markets
12.1.1 Forecasts
12.1.2 Drivers and barriers - global issues
12.2 US
12.2.1 Forecast
12.2.2 Key events
12.2.3 Drivers and barriers
12.3 5EU
12.3.1 Forecast
12.3.2 Key events
12.3.3 Drivers and barriers
12.4 Japan
12.4.1 Forecast
12.4.2 Key events
12.4.3 Drivers and barriers
13 Appendix
13.1 Bibliography
13.2 Abbreviations
13.3 Methodology
13.3.1 Forecasting Methodology
13.4 Primary Research - KOLs Interviewed for This Report
13.4.1 KOLs and Payers
13.5 Primary Research - Prescriber Survey
13.6 About the Authors
13.6.1 Analyst
13.6.2 Therapy Area Director
13.6.3 Epidemiologist
13.6.4 Managing Epidemiologists
13.6.5 Vice President of Disease Analysis and Epidemiology
13.6.6 Global Head of Pharma Research, Analysis and Competitive Intelligence
  • Contact the Publisher
List of Tables
Table 1: Schizophrenia: Key metrics in the 7MM
Table 2: Risk factors and comorbid conditions associated with schizophrenia
Table 3: Treatment Guidelines for Schizophrenia
Table 4: Schizophrenia market - global drivers and barriers, 2021-31
Table 5: Key events impacting sales for schizophrenia in the US, 2021-31
Table 6: Schizophrenia Market - Drivers and Barriers in the US, 2021-31
Table 7: Key events impacting sales for schizophrenia in the 5EU, 2021-31
Table 8: Schizophrenia market - drivers and barriers in the 5EU, 2021-31
Table 9: Key Events Impacting Sales for Schizophrenia in Japan, 2021-31
Table 10: Schizophrenia Market - Drivers and Barriers in Japan, 2021-31
Table 11: High-Prescribing Physicians (non-KOLs) Surveyed, By Country
List of Figures
Figure 1: Global sales forecast by country for schizophrenia in 2021 and 2031
Figure 2: Analysis of the company portfolio gap in schizophrenia during the forecast period
Figure 3: Competitive assessment of oral pipeline products that the analyst expects to be licensed for the treatment of schizophrenia during the forecast period
Figure 4: Competitive assessment of pipeline atypical antipsychotic reformulations benchmarked against the SOC, Invega Sustenna
Figure 5: 7MM, 12-month total prevalence (%) of schizophrenia, both sexes, ages =13 years, 2021
Figure 6: 7MM, 12-month diagnosed prevalence (%) of schizophrenia, men and women, ages =13 years, 2021
Figure 7: 7MM, sources used to forecast the 12-month total prevalent cases of schizophrenia
Figure 8: 7MM, sources used and not used to forecast the 12-month diagnosed prevalent cases of schizophrenia
Figure 9: 7MM, 12-month total prevalent cases of schizophrenia, N, both sexes, ages =13 years, 2021
Figure 10: 7MM, 12-month diagnosed prevalent cases of schizophrenia, N, both sexes, ages =13 years, 2021
Figure 11: 7MM, 12-month diagnosed prevalent cases of schizophrenia by age, N, both sexes, 2021
Figure 12: 7MM, 12-month diagnosed prevalent cases of schizophrenia by sex, N, ages =13 years, 2021
Figure 13: Unmet needs and opportunities in schizophrenia
Figure 14: Overview of the development pipeline in schizophrenia
Figure 15: Key late-stage trials for the promising pipeline agents that the analyst expects to be launched for schizophrenia in the 7MM during the forecast period
Figure 16: Competitive assessment of oral pipeline drugs benchmarked against the SOC, Abilify
Figure 17: Competitive assessment of pipeline atypical antipsychotic reformulations benchmarked against the SOC, Invega Sustenna
Figure 18: Analysis of the company portfolio gap in schizophrenia during the forecast period
Figure 19: Global (7MM) sales forecast by country for schizophrenia in 2021 and 2031
Figure 20: Sales forecast by class for schizophrenia in the 7MM in 2021 and 2031
Figure 21: Sales forecast by class for schizophrenia in the US in 2021 and 2031
Figure 22: Sales forecast by class for schizophrenia in the 5EU in 2021 and 2031
Figure 23: Sales forecast by class for schizophrenia in Japan in 2021 and 2031

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Alexza Pharmaceuticals
  • Alkermes Plc
  • Astellas
  • AstraZeneca
  • Biogen Inc
  • BioXcel Therapeutics Inc
  • Boehringer Ingelheim International GmbH
  • Bristol Myers Squibb
  • Eli Lilly
  • Gedeon Richter
  • Hisamitsu Pharmaceuticals
  • Indivior
  • Intra-Cellular Therapies Inc
  • Johnson & Johnson
  • Laboratorios Farmaceuticos Rovi
  • Lundbeck
  • Luye Pharma Group
  • Lyndra Therapeutics Inc.
  • MedinCell
  • Merck & Co
  • Neurocrine Biosciences Inc
  • Newron Pharmaceuticals SpA
  • Otsuka Pharmaceutical Co Ltd
  • Reviva Pharmaceuticals Inc
  • Sumitomo Dainippon
  • Sumitomo Pharma Co Ltd
  • Teva Pharmaceutical Industries Ltd
  • Vanda Pharmaceuticals Inc