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Acromegaly - Pipeline Review, H2 2020

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    Drug Pipelines

  • 96 Pages
  • September 2020
  • Region: Global
  • Global Markets Direct
  • ID: 5174751
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Summary

The publisher's latest Pharmaceutical and Healthcare disease pipeline guide Acromegaly - Pipeline Review, H2 2020, provides an overview of the Acromegaly (Hormonal Disorders) pipeline landscape.

Acromegaly is a hormonal disorder that develops when pituitary gland produces too much growth hormone during adulthood. Symptoms include body odor, easy fatigue, headache, large feet, excessive height, swelling of the bony areas around a joint, widely spaced teeth and sleep apnea. Treatment includes surgery, dopamine agonists and growth hormone antagonists.

Report Highlights

The publisher's Pharmaceutical and Healthcare latest pipeline guide Acromegaly - Pipeline Review, H2 2020, provides comprehensive information on the therapeutics under development for Acromegaly (Hormonal Disorders), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Acromegaly (Hormonal Disorders) pipeline guide also reviews of key players involved in therapeutic development for Acromegaly and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase III, Phase II, Phase I, Preclinical, Discovery and Unknown stages are 2, 7, 4, 4, 3 and 1 respectively.

Acromegaly (Hormonal Disorders) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from the publisher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content/sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope
  • The pipeline guide provides a snapshot of the global therapeutic landscape of Acromegaly (Hormonal Disorders).
  • The pipeline guide reviews pipeline therapeutics for Acromegaly (Hormonal Disorders) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Acromegaly (Hormonal Disorders) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Acromegaly (Hormonal Disorders) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews latest news related to pipeline therapeutics for Acromegaly (Hormonal Disorders)

Reasons to Buy
  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Acromegaly (Hormonal Disorders).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Acromegaly (Hormonal Disorders) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.

Table of Contents

Introduction
  • Report Coverage

Acromegaly - Overview
Acromegaly - Therapeutics Development
  • Pipeline Overview
  • Pipeline by Companies
  • Products under Development by Companies

Acromegaly - Therapeutics Assessment
  • Assessment by Target
  • Assessment by Mechanism of Action
  • Assessment by Route of Administration
  • Assessment by Molecule Type

Acromegaly - Companies Involved in Therapeutics Development
  • Antisense Therapeutics Ltd
  • Aquestive Therapeutics Inc
  • Ascil Proyectos SL
  • Auritec Pharmaceuticals Inc
  • Camurus AB
  • Chiasma Inc
  • Crinetics Pharmaceuticals Inc
  • Daewoong Pharmaceutical Co Ltd
  • Dauntless Pharmaceuticals Inc
  • DexTech Medical AB
  • Enesi Pharma Ltd
  • Foresee Pharmaceuticals Co Ltd
  • GeneScience Pharmaceuticals Co Ltd
  • GlyTech Inc
  • Ionis Pharmaceuticals Inc
  • Italfarmaco SpA
  • OPKO Health Inc
  • Pharmathen Global BV
  • Strongbridge Biopharma plc

Acromegaly - Drug Profiles
atesidorsen sodium - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

DP-2018 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

FP-002 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

IONIS-GHRLRx - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

ITF-2984 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

lanreotide SR - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

MOD-12014 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

octreotide - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

octreotide acetate - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

octreotide acetate - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

octreotide acetate CR - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

octreotide acetate DR - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

octreotide acetate microspheres - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

octreotide LA - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

octreotide LA - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

octreotide SR - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

paltusotine - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Somadex - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Synthetic Peptides to Agonize Somatostatin Receptors for Acromegaly - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

veldoreotide ER - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

veldoreotide IR - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Acromegaly - Dormant ProjectsAcromegaly - Discontinued Products
Acromegaly - Product Development Milestones
  • Featured News & Press Releases
  • Sep 04, 2020: Crinetics Pharmaceuticals provides new data from Paltusotine and ACTH antagonist development programs at European Congress of Endocrinology
  • Aug 31, 2020: Chiasma announces U.S. commercial launch and availability of MYCAPSSA, the first and only oral somatostatin analog for patients with acromegaly
  • Aug 17, 2020: Chiasma announces publication of pivotal data from the phase 3 CHIASMA OPTIMAL clinical trial in the journal of Clinical Endocrinology & Metabolism
  • Jul 27, 2020: Chiasma announces 48-week safety and efficacy data from the open-label extension study of its CHIASMA OPTIMAL phase 3 trial evaluating MYCAPSSA in patients with acromegaly
  • Jul 08, 2020: Crinetics Pharmaceuticals receives orphan drug designation for Paltusotine for the treatment of acromegaly
  • Jul 02, 2020: Camargo client Chiasma receives FDA approval for first and only oral somatostatin analog for long-term maintenance treatment of acromegaly
  • Jun 26, 2020: Chiasma announces FDA approval of MYCAPSSA (Octreotide) capsules, the first and only oral somatostatin analog
  • Jun 11, 2020: Crinetics Pharmaceuticals confirms completion for half of the enrolled patients in the ongoing phase 2 ACROBAT edge clinical trial for Paltusotine
  • Apr 06, 2020: Crinetics Pharmaceuticals reports positive interim results for the ACROBAT Edge phase 2 trial of Paltusotine (CRN00808) in acromegaly patients and provides corporate update
  • Jan 13, 2020: Chiasma announces FDA acceptance of MYCAPSSA New Drug Application Resubmission
  • Aug 26, 2019: Acromegaly early access program - status update
  • Jul 23, 2019: Chiasma announces positive phase 3 top-line results from CHIASMA OPTIMAL clinical trial of Mycapssa for the maintenance treatment of adults with Acromegaly
  • Jun 27, 2019: Chiasma provides update on ongoing Mycapssa phase 3 clinical trials
  • Jun 20, 2019: Camurus Receives IND Acceptance From the FDA to Enter Phase 3 with CAM2029 for Treatment of Acromegaly
  • Jun 05, 2019: Chiasma strengthens leadership team ahead of anticipated commercial availability of Mycapssa

Appendix
  • Methodology
  • Coverage
  • Secondary Research
  • Primary Research
  • Expert Panel Validation
  • Contact
  • Disclaimer

List of Tables
  • Number of Products under Development for Acromegaly, H2 2020
  • Number of Products under Development by Companies, H2 2020
  • Products under Development by Companies, H2 2020
  • Products under Development by Companies, H2 2020 (Contd..1), H2 2020
  • Number of Products by Stage and Target, H2 2020
  • Number of Products by Stage and Mechanism of Action, H2 2020
  • Number of Products by Stage and Route of Administration, H2 2020
  • Number of Products by Stage and Molecule Type, H2 2020
  • Acromegaly - Pipeline by Antisense Therapeutics Ltd, H2 2020
  • Acromegaly - Pipeline by Aquestive Therapeutics Inc, H2 2020
  • Acromegaly - Pipeline by Ascil Proyectos SL, H2 2020
  • Acromegaly - Pipeline by Auritec Pharmaceuticals Inc, H2 2020
  • Acromegaly - Pipeline by Camurus AB, H2 2020
  • Acromegaly - Pipeline by Chiasma Inc, H2 2020
  • Acromegaly - Pipeline by Crinetics Pharmaceuticals Inc, H2 2020
  • Acromegaly - Pipeline by Daewoong Pharmaceutical Co Ltd, H2 2020
  • Acromegaly - Pipeline by Dauntless Pharmaceuticals Inc, H2 2020
  • Acromegaly - Pipeline by DexTech Medical AB, H2 2020
  • Acromegaly - Pipeline by Enesi Pharma Ltd, H2 2020
  • Acromegaly - Pipeline by Foresee Pharmaceuticals Co Ltd, H2 2020
  • Acromegaly - Pipeline by GeneScience Pharmaceuticals Co Ltd, H2 2020
  • Acromegaly - Pipeline by GlyTech Inc, H2 2020
  • Acromegaly - Pipeline by Ionis Pharmaceuticals Inc, H2 2020
  • Acromegaly - Pipeline by Italfarmaco SpA, H2 2020
  • Acromegaly - Pipeline by OPKO Health Inc, H2 2020
  • Acromegaly - Pipeline by Pharmathen Global BV, H2 2020
  • Acromegaly - Pipeline by Strongbridge Biopharma plc, H2 2020
  • Acromegaly - Dormant Projects, H2 2020
  • Acromegaly - Discontinued Products, H2 2020

List of Figures
  • Number of Products under Development for Acromegaly, H2 2020
  • Number of Products under Development by Companies, H2 2020
  • Number of Products by Targets, H2 2020
  • Number of Products by Stage and Targets, H2 2020
  • Number of Products by Mechanism of Actions, H2 2020
  • Number of Products by Stage and Mechanism of Actions, H2 2020
  • Number of Products by Routes of Administration, H2 2020
  • Number of Products by Stage and Routes of Administration, H2 2020
  • Number of Products by Molecule Types, H2 2020
  • Number of Products by Stage and Molecule Types, H2 2020

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Antisense Therapeutics Ltd
  • Aquestive Therapeutics Inc
  • Ascil Proyectos SL
  • Auritec Pharmaceuticals Inc
  • Camurus AB
  • Chiasma Inc
  • Crinetics Pharmaceuticals Inc
  • Daewoong Pharmaceutical Co Ltd
  • Dauntless Pharmaceuticals Inc
  • DexTech Medical AB
  • Enesi Pharma Ltd
  • Foresee Pharmaceuticals Co Ltd
  • GeneScience Pharmaceuticals Co Ltd
  • GlyTech Inc
  • Ionis Pharmaceuticals Inc
  • Italfarmaco SpA
  • OPKO Health Inc
  • Pharmathen Global BV
  • Strongbridge Biopharma plc