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Alpha-1 Antitrypsin Drugs - Global Strategic Business Report

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    Report

  • 193 Pages
  • November 2024
  • Region: Global
  • Global Industry Analysts, Inc
  • ID: 5309396
The global market for Alpha-1 Antitrypsin Drugs was estimated at US$2.3 Billion in 2023 and is projected to reach US$4.5 Billion by 2030, growing at a CAGR of 9.6% from 2023 to 2030. This comprehensive report provides an in-depth analysis of market trends, drivers, and forecasts, helping you make informed business decisions.

Alpha-1 Antitrypsin (AAT) deficiency is a genetic disorder that can lead to severe respiratory and liver diseases. This condition results from a lack of alpha-1 antitrypsin, a protein produced by the liver that protects the lungs from inflammation caused by infection or irritants like tobacco smoke. Individuals with AAT deficiency are at a higher risk of developing chronic obstructive pulmonary disease (COPD), emphysema, and liver diseases such as cirrhosis and liver cancer. The need for effective drugs is critical, as untreated AAT deficiency can severely impact a patient's quality of life and reduce life expectancy. Current treatments aim to supplement the deficient protein, slow disease progression, and manage symptoms to improve overall health outcomes.

How Are Technological Advancements Influencing Alpha-1 Antitrypsin Drug Development?

Technological advancements have significantly influenced the development of Alpha-1 Antitrypsin drugs, enhancing their efficacy and delivery. Innovations in drug delivery systems, such as inhalable therapies and advanced infusion methods, have improved the convenience and effectiveness of treatment, making it easier for patients to adhere to their medication regimens. Additionally, breakthroughs in genetic and molecular research have paved the way for novel therapies, including gene therapy and recombinant DNA technology, which offer the potential for more targeted and long-lasting treatments. These advancements not only improve patient outcomes but also reduce the frequency of administration and associated healthcare costs, making treatment more accessible and manageable for patients.

What Trends Are Driving the Demand for Alpha-1 Antitrypsin Drugs?

Several trends are driving the increasing demand for Alpha-1 Antitrypsin drugs. Rising awareness and improved diagnostic techniques have led to earlier and more accurate detection of AAT deficiency, resulting in timely treatment initiation. The expanding applications of AAT drugs in treating a broader range of pulmonary and hepatic diseases have also contributed to their growing demand. Moreover, regulatory approvals and support for innovative therapies have accelerated the availability of new treatments in the market. The increasing investment in research and development by pharmaceutical companies highlights the ongoing commitment to improving and expanding treatment options. Furthermore, the growing number of patient advocacy and support groups plays a crucial role in educating the public and healthcare providers about AAT deficiency, driving further demand for effective treatments.

What Factors Are Propelling the Growth of the Alpha-1 Antitrypsin Drugs Market?

The growth in the Alpha-1 Antitrypsin drugs market is driven by several factors, primarily technological advancements, expanding therapeutic applications, and evolving healthcare landscapes. Technological innovations in drug development and delivery systems have significantly enhanced the efficacy and convenience of AAT therapies, making them more attractive to patients and healthcare providers. Expanding therapeutic applications in pulmonary and hepatic diseases have broadened the market, creating new opportunities for drug manufacturers. Additionally, evolving healthcare landscapes, including increased healthcare expenditure and better diagnostic capabilities in emerging markets, have facilitated wider adoption of AAT therapies. Strategic collaborations between pharmaceutical companies and research institutions are accelerating the development of new and innovative treatments. Furthermore, regulatory support and the rise of personalized medicine are driving the adoption of customized AAT therapies tailored to individual patient needs, ensuring a robust growth trajectory for the market in the coming years.

Key Insights:

  • Market Growth: Understand the significant growth trajectory of the Prolastin C Drug segment, which is expected to reach US$2.1 Billion by 2030 with a CAGR of a 9.4%. The Glassia Drug segment is also set to grow at 10.4% CAGR over the analysis period.
  • Regional Analysis: Gain insights into the U.S. market, which was estimated at $651.1 Million in 2023, and China, forecasted to grow at an impressive 9.0% CAGR to reach $679.8 Million by 2030. Discover growth trends in other key regions, including Japan, Canada, Germany, and the Asia-Pacific.

Why You Should Buy This Report:

  • Detailed Market Analysis: Access a thorough analysis of the Global Alpha-1 Antitrypsin Drugs Market, covering all major geographic regions and market segments.
  • Competitive Insights: Get an overview of the competitive landscape, including the market presence of major players across different geographies.
  • Future Trends and Drivers: Understand the key trends and drivers shaping the future of the Global Alpha-1 Antitrypsin Drugs Market.
  • Actionable Insights: Benefit from actionable insights that can help you identify new revenue opportunities and make strategic business decisions.

Key Questions Answered:

  • How is the Global Alpha-1 Antitrypsin Drugs Market expected to evolve by 2030?
  • What are the main drivers and restraints affecting the market?
  • Which market segments will grow the most over the forecast period?
  • How will market shares for different regions and segments change by 2030?
  • Who are the leading players in the market, and what are their prospects?

Report Features:

  • Comprehensive Market Data: Independent analysis of annual sales and market forecasts in US$ Million from 2023 to 2030.
  • In-Depth Regional Analysis: Detailed insights into key markets, including the U.S., China, Japan, Canada, Europe, Asia-Pacific, Latin America, Middle East, and Africa.
  • Company Profiles: Coverage of major players such as Abeona Therapeutics, Alnylam Pharmaceuticals, Applied Genetic Technologies Corp, and more.
  • Complimentary Updates: Receive free report updates for one year to keep you informed of the latest market developments.

Select Competitors (Total 43 Featured):

  • Abeona Therapeutics
  • Alnylam Pharmaceuticals
  • Applied Genetic Technologies Corp
  • Arrowhead Research Corporation
  • Baxalta
  • Baxter
  • CSL Behring
  • Grifols
  • Kamada
  • Shire
  • Takeda Pharmaceutical Company Limited

Table of Contents

I. METHODOLOGYII. EXECUTIVE SUMMARY
1. MARKET OVERVIEW
  • Influencer Market Insights
  • Alpha-1 Antitrypsin Drugs - Global Key Competitors Percentage Market Share in 2024 (E)
  • Global Economic Update
  • Competitive Market Presence - Strong/Active/Niche/Trivial for Players Worldwide in 2024 (E)
2. FOCUS ON SELECT PLAYERS
3. MARKET TRENDS & DRIVERS
  • Increasing Prevalence of Alpha-1 Antitrypsin Deficiency Propels Demand for Treatment
  • Rising Awareness and Diagnosis Rates Expand Addressable Market Opportunity
  • Innovations in Genetic Therapies Generate Demand for Advanced Alpha-1 Antitrypsin Treatments
  • Growth in Biopharmaceutical Sector Accelerates Development of Alpha-1 Antitrypsin Drugs
  • Expanding Applications in Pulmonary and Hepatic Diseases Drive Market Growth
  • Advances in Biomarker Identification Generate New Opportunities for Targeted Therapies
  • Global Trends towards Personalized Medicine Drive Adoption of Customized Treatments
  • Increasing Focus on Rare Disease Treatment Expands Addressable Market Opportunity for Alpha-1 Antitrypsin Drugs
4. GLOBAL MARKET PERSPECTIVE
  • TABLE 1: World Alpha-1 Antitrypsin Drugs Market Analysis of Annual Sales in US$ Thousand for Years 2014 through 2030
  • TABLE 2: World Recent Past, Current & Future Analysis for Alpha-1 Antitrypsin Drugs by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • TABLE 3: World Historic Review for Alpha-1 Antitrypsin Drugs by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 4: World 16-Year Perspective for Alpha-1 Antitrypsin Drugs by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets for Years 2014, 2024 & 2030
  • TABLE 5: World Recent Past, Current & Future Analysis for Prolastin C by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • TABLE 6: World Historic Review for Prolastin C by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 7: World 16-Year Perspective for Prolastin C by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • TABLE 8: World Recent Past, Current & Future Analysis for Glassia by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • TABLE 9: World Historic Review for Glassia by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 10: World 16-Year Perspective for Glassia by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • TABLE 11: World Recent Past, Current & Future Analysis for Aralast NP by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • TABLE 12: World Historic Review for Aralast NP by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 13: World 16-Year Perspective for Aralast NP by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • TABLE 14: World Recent Past, Current & Future Analysis for Zemaira / Respreeza by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • TABLE 15: World Historic Review for Zemaira / Respreeza by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 16: World 16-Year Perspective for Zemaira / Respreeza by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
III. MARKET ANALYSIS
UNITED STATES
  • Alpha-1 Antitrypsin Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in the United States for 2024 (E)
  • TABLE 17: USA Recent Past, Current & Future Analysis for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • TABLE 18: USA Historic Review for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 19: USA 16-Year Perspective for Alpha-1 Antitrypsin Drugs by Drug Type - Percentage Breakdown of Value Sales for Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza for the Years 2014, 2024 & 2030
CANADA
  • TABLE 20: Canada Recent Past, Current & Future Analysis for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • TABLE 21: Canada Historic Review for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 22: Canada 16-Year Perspective for Alpha-1 Antitrypsin Drugs by Drug Type - Percentage Breakdown of Value Sales for Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza for the Years 2014, 2024 & 2030
JAPAN
  • Alpha-1 Antitrypsin Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Japan for 2024 (E)
  • TABLE 23: Japan Recent Past, Current & Future Analysis for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • TABLE 24: Japan Historic Review for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 25: Japan 16-Year Perspective for Alpha-1 Antitrypsin Drugs by Drug Type - Percentage Breakdown of Value Sales for Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza for the Years 2014, 2024 & 2030
CHINA
  • Alpha-1 Antitrypsin Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in China for 2024 (E)
  • TABLE 26: China Recent Past, Current & Future Analysis for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • TABLE 27: China Historic Review for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 28: China 16-Year Perspective for Alpha-1 Antitrypsin Drugs by Drug Type - Percentage Breakdown of Value Sales for Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza for the Years 2014, 2024 & 2030
EUROPE
  • Alpha-1 Antitrypsin Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Europe for 2024 (E)
  • TABLE 29: Europe Recent Past, Current & Future Analysis for Alpha-1 Antitrypsin Drugs by Geographic Region - France, Germany, Italy, UK and Rest of Europe Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • TABLE 30: Europe Historic Review for Alpha-1 Antitrypsin Drugs by Geographic Region - France, Germany, Italy, UK and Rest of Europe Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 31: Europe 16-Year Perspective for Alpha-1 Antitrypsin Drugs by Geographic Region - Percentage Breakdown of Value Sales for France, Germany, Italy, UK and Rest of Europe Markets for Years 2014, 2024 & 2030
  • TABLE 32: Europe Recent Past, Current & Future Analysis for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • TABLE 33: Europe Historic Review for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 34: Europe 16-Year Perspective for Alpha-1 Antitrypsin Drugs by Drug Type - Percentage Breakdown of Value Sales for Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza for the Years 2014, 2024 & 2030
FRANCE
  • Alpha-1 Antitrypsin Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in France for 2024 (E)
  • TABLE 35: France Recent Past, Current & Future Analysis for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • TABLE 36: France Historic Review for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 37: France 16-Year Perspective for Alpha-1 Antitrypsin Drugs by Drug Type - Percentage Breakdown of Value Sales for Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza for the Years 2014, 2024 & 2030
GERMANY
  • Alpha-1 Antitrypsin Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Germany for 2024 (E)
  • TABLE 38: Germany Recent Past, Current & Future Analysis for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • TABLE 39: Germany Historic Review for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 40: Germany 16-Year Perspective for Alpha-1 Antitrypsin Drugs by Drug Type - Percentage Breakdown of Value Sales for Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza for the Years 2014, 2024 & 2030
ITALY
  • TABLE 41: Italy Recent Past, Current & Future Analysis for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • TABLE 42: Italy Historic Review for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 43: Italy 16-Year Perspective for Alpha-1 Antitrypsin Drugs by Drug Type - Percentage Breakdown of Value Sales for Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza for the Years 2014, 2024 & 2030
UNITED KINGDOM
  • Alpha-1 Antitrypsin Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in the United Kingdom for 2024 (E)
  • TABLE 44: UK Recent Past, Current & Future Analysis for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • TABLE 45: UK Historic Review for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 46: UK 16-Year Perspective for Alpha-1 Antitrypsin Drugs by Drug Type - Percentage Breakdown of Value Sales for Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza for the Years 2014, 2024 & 2030
REST OF EUROPE
  • TABLE 47: Rest of Europe Recent Past, Current & Future Analysis for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • TABLE 48: Rest of Europe Historic Review for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 49: Rest of Europe 16-Year Perspective for Alpha-1 Antitrypsin Drugs by Drug Type - Percentage Breakdown of Value Sales for Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza for the Years 2014, 2024 & 2030
ASIA-PACIFIC
  • Alpha-1 Antitrypsin Drugs Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Asia-Pacific for 2024 (E)
  • TABLE 50: Asia-Pacific Recent Past, Current & Future Analysis for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • TABLE 51: Asia-Pacific Historic Review for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 52: Asia-Pacific 16-Year Perspective for Alpha-1 Antitrypsin Drugs by Drug Type - Percentage Breakdown of Value Sales for Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza for the Years 2014, 2024 & 2030
REST OF WORLD
  • TABLE 53: Rest of World Recent Past, Current & Future Analysis for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • TABLE 54: Rest of World Historic Review for Alpha-1 Antitrypsin Drugs by Drug Type - Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • TABLE 55: Rest of World 16-Year Perspective for Alpha-1 Antitrypsin Drugs by Drug Type - Percentage Breakdown of Value Sales for Prolastin C, Glassia, Aralast NP and Zemaira / Respreeza for the Years 2014, 2024 & 2030
IV. COMPETITION

Companies Mentioned

  • Abeona Therapeutics
  • Alnylam Pharmaceuticals
  • Applied Genetic Technologies Corp
  • Arrowhead Research Corporation
  • Baxalta
  • Baxter
  • CSL Behring
  • Grifols
  • Kamada
  • Shire
  • Takeda Pharmaceutical Company Limited

Table Information