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Hypercalcemia Treatment - Global Strategic Business Report

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    Report

  • 192 Pages
  • November 2024
  • Region: Global
  • Global Industry Analysts, Inc
  • ID: 5309461
The global market for Hypercalcemia Treatment was estimated at US$22.9 Billion in 2023 and is projected to reach US$42.8 Billion by 2030, growing at a CAGR of 9.3% from 2023 to 2030. This comprehensive report provides an in-depth analysis of market trends, drivers, and forecasts, helping you make informed business decisions.

Is Hypercalcemia Treatment the Key to Preventing Serious Health Complications in Cancer and Kidney Disease Patients?

Hypercalcemia, characterized by abnormally high levels of calcium in the blood, poses serious health risks, but why is effective treatment so critical for conditions like cancer, kidney disease, and certain hormonal disorders? Hypercalcemia often occurs as a complication of these underlying conditions, and if left untreated, it can lead to severe complications such as kidney stones, bone pain, heart rhythm disturbances, and even life-threatening issues like kidney failure or coma. The condition can be triggered by malignancies, especially cancers of the lung, breast, and multiple myeloma, as well as hyperparathyroidism, where the parathyroid glands overproduce hormones, raising calcium levels.

The significance of hypercalcemia treatment lies in its ability to quickly reduce dangerously high calcium levels, thus preventing irreversible damage to vital organs. Treatments vary depending on the severity of hypercalcemia and the underlying cause. In mild cases, lifestyle modifications such as hydration or limiting calcium intake may be sufficient. In more severe cases, medications, intravenous fluids, and even dialysis may be necessary to lower calcium levels and stabilize the patient. Early detection and appropriate treatment of hypercalcemia are critical to avoiding complications and improving patient outcomes, especially in those already battling serious illnesses.

How Have Technological and Pharmacological Advancements Improved Hypercalcemia Treatment Options?

Technological and pharmacological advancements have significantly improved the treatment of hypercalcemia, allowing for more effective management of calcium levels and better patient outcomes. One of the most important advancements in the pharmacological treatment of hypercalcemia is the development of bisphosphonates. Bisphosphonates, such as zoledronic acid and pamidronate, work by inhibiting bone resorption, a process where calcium is released into the bloodstream from bones. These medications are particularly effective in managing hypercalcemia caused by cancers that affect the bones, such as multiple myeloma or metastatic breast cancer. Bisphosphonates can lower calcium levels quickly and are now considered the first-line treatment for hypercalcemia of malignancy.

Calcitonin, a hormone that helps regulate calcium levels in the blood, has also been an important advancement in treating hypercalcemia. Calcitonin therapy works by inhibiting the activity of osteoclasts, cells that break down bone and release calcium into the bloodstream. This treatment is especially beneficial for patients who need a rapid reduction in calcium levels, such as those in acute hypercalcemic crises. While calcitonin is often used as a short-term solution due to its potential for diminishing effectiveness over time, it remains a valuable tool in managing severe hypercalcemia, particularly in combination with bisphosphonates for longer-term control.

Another key advancement is the use of monoclonal antibodies like denosumab in treating hypercalcemia, particularly in cancer patients who do not respond to bisphosphonates. Denosumab targets and inhibits RANK ligand, a protein that activates osteoclasts responsible for bone breakdown. By blocking this pathway, denosumab reduces calcium release from bones, effectively lowering blood calcium levels. This treatment is especially beneficial for patients with hypercalcemia caused by bone metastases or for those who are intolerant to bisphosphonates. The introduction of denosumab has expanded treatment options for patients with refractory hypercalcemia, offering an effective alternative for long-term management.

Hydration therapy is another critical component in managing hypercalcemia, and recent advancements in intravenous (IV) fluid administration techniques have improved the speed and efficiency of this treatment. Hydration helps dilute the calcium concentration in the blood and increases calcium excretion through the kidneys. In moderate to severe cases of hypercalcemia, patients are often treated with IV saline to quickly restore fluid balance and promote renal clearance of calcium. Advances in IV delivery systems have improved patient comfort, and real-time monitoring of hydration status ensures that treatment can be adjusted quickly to achieve optimal results without causing fluid overload, particularly in patients with kidney or heart disease.

Loop diuretics, such as furosemide, are often used in conjunction with hydration therapy to enhance calcium excretion by the kidneys. While traditionally used to manage fluid overload, loop diuretics can also accelerate the removal of calcium from the bloodstream when used in patients who are appropriately hydrated. This combination therapy is particularly effective in reducing calcium levels in patients with moderate hypercalcemia. However, the careful management of hydration is essential to avoid dehydration and electrolyte imbalances. Modern treatment protocols now emphasize precise dosing and careful monitoring of kidney function to maximize the benefits of loop diuretics in hypercalcemia treatment.

For patients with hypercalcemia related to hyperparathyroidism, surgical removal of the overactive parathyroid glands remains the most effective long-term solution. Advances in minimally invasive surgical techniques, such as targeted parathyroidectomy, have made this procedure safer and more efficient, with shorter recovery times and reduced risk of complications. Preoperative imaging techniques, such as sestamibi scans and ultrasound, help pinpoint the exact location of the overactive glands, allowing for more precise surgery. These technological advancements have improved the outcomes of parathyroid surgery, particularly in patients with primary hyperparathyroidism, a common cause of hypercalcemia.

In cases where surgery is not an option, cinacalcet, a calcimimetic agent, offers an alternative treatment for hypercalcemia caused by hyperparathyroidism. Cinacalcet works by reducing parathyroid hormone (PTH) secretion, which in turn lowers calcium levels in the blood. This medication is particularly useful for patients with secondary hyperparathyroidism, such as those with chronic kidney disease, who may not be candidates for surgery. Cinacalcet has become an important option in the pharmacological management of hypercalcemia, providing effective calcium control without the need for invasive procedures.

Why Is Hypercalcemia Treatment Critical for Cancer, Kidney Disease, and Endocrine Disorders?

Hypercalcemia treatment is critical for managing cancer, kidney disease, and endocrine disorders because elevated calcium levels can lead to life-threatening complications if not addressed promptly. In cancer patients, particularly those with bone metastases or hematologic cancers like multiple myeloma, hypercalcemia is a common and dangerous complication. The excess calcium can impair kidney function, leading to dehydration, kidney stones, or even renal failure. Additionally, high calcium levels can cause neurological symptoms such as confusion, lethargy, and in severe cases, coma. Hypercalcemia of malignancy is associated with a poor prognosis, making rapid and effective treatment essential to improving patient outcomes and quality of life.

In the context of kidney disease, hypercalcemia poses unique challenges. Patients with chronic kidney disease (CKD) often have impaired calcium and phosphate balance due to decreased kidney function. Hypercalcemia can exacerbate kidney damage and increase the risk of vascular calcification, which can lead to cardiovascular complications. In dialysis patients, hypercalcemia can be caused by the use of calcium-based phosphate binders or the overproduction of parathyroid hormone (secondary hyperparathyroidism). Managing calcium levels in CKD patients is crucial to preventing further kidney deterioration and reducing the risk of cardiovascular events, making hypercalcemia treatment a vital part of overall kidney disease management.

Endocrine disorders, particularly hyperparathyroidism, are a major cause of hypercalcemia and require targeted treatment to prevent long-term complications. In primary hyperparathyroidism, the parathyroid glands secrete excess parathyroid hormone (PTH), leading to elevated calcium levels. This can result in weakened bones (osteoporosis), kidney stones, and other complications if left untreated. Parathyroidectomy, the surgical removal of the overactive parathyroid glands, is often the most effective treatment for this condition. However, when surgery is not feasible, medications such as cinacalcet can help control calcium levels. Effective treatment of hyperparathyroidism is essential for preventing the progression of bone and kidney damage and improving patient outcomes.

Hypercalcemia treatment is also critical for preventing acute complications that can arise from severe elevations in calcium levels, such as hypercalcemic crisis. In a hypercalcemic crisis, calcium levels rise to dangerous levels, leading to dehydration, kidney failure, cardiac arrhythmias, and neurological symptoms. This condition requires immediate intervention, often with intravenous fluids, bisphosphonates, and sometimes dialysis to rapidly reduce calcium levels and stabilize the patient. Hypercalcemia crises are medical emergencies, and without prompt treatment, they can lead to coma and death. Thus, effective management of hypercalcemia is essential for preventing these life-threatening events.

In cancer patients, controlling hypercalcemia is critical not only for managing symptoms but also for improving tolerance to cancer treatments. Hypercalcemia can cause fatigue, nausea, vomiting, and cognitive impairment, all of which can make it difficult for patients to adhere to chemotherapy, radiation, or other cancer treatments. By lowering calcium levels and addressing the symptoms of hypercalcemia, patients are more likely to tolerate their cancer therapies and maintain a better quality of life. Additionally, effective hypercalcemia management can reduce the risk of hospitalizations and improve overall survival rates in cancer patients.

For patients with chronic conditions like kidney disease or hyperparathyroidism, ongoing management of calcium levels is essential to prevent long-term complications. Hypercalcemia can accelerate bone loss, increase the risk of fractures, and contribute to the development of cardiovascular disease. By keeping calcium levels within a normal range, these risks can be mitigated, leading to better long-term health outcomes. Early detection and treatment of hypercalcemia in these populations are crucial for preventing irreversible damage to organs such as the kidneys, heart, and bones.

What Factors Are Driving the Growth of the Hypercalcemia Treatment Market?

Several factors are driving the growth of the hypercalcemia treatment market, including the increasing prevalence of cancer, the rising incidence of kidney disease, advancements in endocrine disorder management, and the development of new pharmacological therapies. One of the primary drivers is the growing burden of cancer worldwide, particularly cancers associated with bone metastases, such as breast, lung, and prostate cancers. As cancer treatment options improve and patients live longer, the management of cancer-related complications, including hypercalcemia, has become a critical aspect of oncological care. The availability of bisphosphonates, denosumab, and calcitonin as effective treatments for hypercalcemia of malignancy has expanded the therapeutic options available to clinicians, driving market growth.

The increasing prevalence of chronic kidney disease (CKD) and end-stage renal disease (ESRD) is another significant factor contributing to the expansion of the hypercalcemia treatment market. As kidney function declines, patients often experience disturbances in calcium and phosphate metabolism, leading to secondary hyperparathyroidism and hypercalcemia. The development of medications like cinacalcet, which target the underlying hormonal imbalances, has provided new treatment options for CKD patients, particularly those on dialysis. The growing number of individuals diagnosed with CKD and ESRD, coupled with advances in treatment, is driving demand for hypercalcemia therapies in this patient population.

Advances in endocrinology and the management of hyperparathyroidism have also contributed to the market's growth. Primary hyperparathyroidism is one of the most common causes of hypercalcemia, particularly in older adults, and the demand for both surgical and pharmacological treatments for this condition is rising. Minimally invasive parathyroidectomy procedures and the introduction of calcimimetic agents like cinacalcet have provided more effective and less invasive options for managing hypercalcemia caused by parathyroid disorders. As the population ages and the incidence of hyperparathyroidism increases, the demand for targeted hypercalcemia treatments is expected to grow.

Pharmacological advancements, particularly in the development of novel therapies like denosumab, are also driving growth in the hypercalcemia treatment market. Denosumab offers an alternative to bisphosphonates, particularly for patients who do not respond to or cannot tolerate these medications. Its ability to effectively reduce calcium levels in cancer patients with bone metastases has expanded the treatment options for hypercalcemia, especially in refractory cases. The ongoing development of new drugs targeting calcium metabolism is expected to further drive market expansion as more effective and specialized treatments become available.

The increasing awareness of hypercalcemia and its associated risks is another key factor contributing to market growth. Healthcare providers are becoming more proactive in screening for and managing hypercalcemia, particularly in high-risk populations such as cancer patients, individuals with kidney disease, and those with hyperparathyroidism. Early detection and treatment of hypercalcemia are critical for preventing complications, and as awareness of the condition grows, so does the demand for effective therapies.

Government initiatives and healthcare investments aimed at improving cancer care, kidney disease management, and endocrine disorder treatments are also supporting the growth of the hypercalcemia treatment market. Many countries are prioritizing the development of comprehensive treatment programs for chronic diseases, including cancer and kidney disease, which often include the management of complications like hypercalcemia. These initiatives are driving the adoption of hypercalcemia therapies in both hospital and outpatient settings, further expanding the market.

With the rising prevalence of cancer, kidney disease, and endocrine disorders, coupled with advancements in pharmacological treatments and surgical techniques, the hypercalcemia treatment market is poised for continued growth. As more effective therapies are developed and awareness of hypercalcemia increases, the market will continue to expand, providing critical solutions for managing this serious and potentially life-threatening condition across a wide range of patient populations.

Key Insights:

  • Market Growth: Understand the significant growth trajectory of the Bisphosphonates segment, which is expected to reach US$28.0 Billion by 2030 with a CAGR of a 9.3%. The Calcitonin segment is also set to grow at 8.7% CAGR over the analysis period.
  • Regional Analysis: Gain insights into the U.S. market, which was valued at $6.4 Billion in 2023, and China, forecasted to grow at an impressive 8.6% CAGR to reach $6.5 Billion by 2030. Discover growth trends in other key regions, including Japan, Canada, Germany, and the Asia-Pacific.

Why You Should Buy This Report:

  • Detailed Market Analysis: Access a thorough analysis of the Global Hypercalcemia Treatment Market, covering all major geographic regions and market segments.
  • Competitive Insights: Get an overview of the competitive landscape, including the market presence of major players across different geographies.
  • Future Trends and Drivers: Understand the key trends and drivers shaping the future of the Global Hypercalcemia Treatment Market.
  • Actionable Insights: Benefit from actionable insights that can help you identify new revenue opportunities and make strategic business decisions.

Key Questions Answered:

  • How is the Global Hypercalcemia Treatment Market expected to evolve by 2030?
  • What are the main drivers and restraints affecting the market?
  • Which market segments will grow the most over the forecast period?
  • How will market shares for different regions and segments change by 2030?
  • Who are the leading players in the market, and what are their prospects?

Report Features:

  • Comprehensive Market Data: Independent analysis of annual sales and market forecasts in US$ Million from 2023 to 2030.
  • In-Depth Regional Analysis: Detailed insights into key markets, including the U.S., China, Japan, Canada, Europe, Asia-Pacific, Latin America, Middle East, and Africa.
  • Company Profiles: Coverage of major players such as AbbVie, Inc., Amgen, Inc., DiaSorin SpA, and more.
  • Complimentary Updates: Receive free report updates for one year to keep you informed of the latest market developments.

Select Competitors (Total 38 Featured):

  • AbbVie, Inc.
  • Amgen, Inc.
  • DiaSorin SpA
  • Fujirebio Europe NV
  • Kyowa Hakko Kirin Co., Ltd.
  • Merck & Co., Inc.
  • Novartis AG
  • Opko Health, Inc.
  • Rockwell Medical

Table of Contents

I. METHODOLOGYII. EXECUTIVE SUMMARY
1. MARKET OVERVIEW
  • Influencer Market Insights
  • World Market Trajectories
  • Global Economic Update
  • Hypercalcemia Treatment - Global Key Competitors Percentage Market Share in 2024 (E)
  • Competitive Market Presence - Strong/Active/Niche/Trivial for Players Worldwide in 2024 (E)
2. FOCUS ON SELECT PLAYERS
3. MARKET TRENDS & DRIVERS
  • Rising Incidence of Cancer-related Hypercalcemia Drives Growth in the Hypercalcemia Treatment Market
  • Expansion of Geriatric Population and Chronic Kidney Disease Cases Spurs Adoption of Hypercalcemia Treatments
  • Growth in Focus on Early Diagnosis and Effective Management Expands Addressable Market for Hypercalcemia Treatment
  • Role of Bisphosphonates and Calcimimetics in Managing Hypercalcemia Strengthens Business Case for Adoption
  • Growth in Use of Hypercalcemia Treatments in Oncology and Nephrology Expands Market Opportunities
  • Growth in Demand for Hypercalcemia Treatments in Postmenopausal Osteoporosis Fuels Market Expansion
4. GLOBAL MARKET PERSPECTIVE
  • Table 1: World Hypercalcemia Treatment Market Analysis of Annual Sales in US$ Million for Years 2014 through 2030
  • Table 2: World Recent Past, Current & Future Analysis for Hypercalcemia Treatment by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2023 through 2030 and % CAGR
  • Table 3: World Historic Review for Hypercalcemia Treatment by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 4: World 16-Year Perspective for Hypercalcemia Treatment by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets for Years 2014, 2024 & 2030
  • Table 5: World Recent Past, Current & Future Analysis for Bisphosphonates by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2023 through 2030 and % CAGR
  • Table 6: World Historic Review for Bisphosphonates by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 7: World 16-Year Perspective for Bisphosphonates by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • Table 8: World Recent Past, Current & Future Analysis for Calcitonin by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2023 through 2030 and % CAGR
  • Table 9: World Historic Review for Calcitonin by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 10: World 16-Year Perspective for Calcitonin by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • Table 11: World Recent Past, Current & Future Analysis for Glucocorticoids by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2023 through 2030 and % CAGR
  • Table 12: World Historic Review for Glucocorticoids by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 13: World 16-Year Perspective for Glucocorticoids by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • Table 14: World Recent Past, Current & Future Analysis for Calcimimetic Agents by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2023 through 2030 and % CAGR
  • Table 15: World Historic Review for Calcimimetic Agents by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 16: World 16-Year Perspective for Calcimimetic Agents by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • Table 17: World Recent Past, Current & Future Analysis for Denusomab by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2023 through 2030 and % CAGR
  • Table 18: World Historic Review for Denusomab by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 19: World 16-Year Perspective for Denusomab by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
III. MARKET ANALYSIS
UNITED STATES
  • Hypercalcemia Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in the United States for 2024 (E)
  • Table 20: USA Recent Past, Current & Future Analysis for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
  • Table 21: USA Historic Review for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 22: USA 16-Year Perspective for Hypercalcemia Treatment by Drug Class - Percentage Breakdown of Value Sales for Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab for the Years 2014, 2024 & 2030
CANADA
  • Table 23: Canada Recent Past, Current & Future Analysis for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
  • Table 24: Canada Historic Review for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 25: Canada 16-Year Perspective for Hypercalcemia Treatment by Drug Class - Percentage Breakdown of Value Sales for Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab for the Years 2014, 2024 & 2030
JAPAN
  • Hypercalcemia Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Japan for 2024 (E)
  • Table 26: Japan Recent Past, Current & Future Analysis for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
  • Table 27: Japan Historic Review for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 28: Japan 16-Year Perspective for Hypercalcemia Treatment by Drug Class - Percentage Breakdown of Value Sales for Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab for the Years 2014, 2024 & 2030
CHINA
  • Hypercalcemia Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in China for 2024 (E)
  • Table 29: China Recent Past, Current & Future Analysis for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
  • Table 30: China Historic Review for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 31: China 16-Year Perspective for Hypercalcemia Treatment by Drug Class - Percentage Breakdown of Value Sales for Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab for the Years 2014, 2024 & 2030
EUROPE
  • Hypercalcemia Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Europe for 2024 (E)
  • Table 32: Europe Recent Past, Current & Future Analysis for Hypercalcemia Treatment by Geographic Region - France, Germany, Italy, UK and Rest of Europe Markets - Independent Analysis of Annual Sales in US$ Million for Years 2023 through 2030 and % CAGR
  • Table 33: Europe Historic Review for Hypercalcemia Treatment by Geographic Region - France, Germany, Italy, UK and Rest of Europe Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 34: Europe 16-Year Perspective for Hypercalcemia Treatment by Geographic Region - Percentage Breakdown of Value Sales for France, Germany, Italy, UK and Rest of Europe Markets for Years 2014, 2024 & 2030
  • Table 35: Europe Recent Past, Current & Future Analysis for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
  • Table 36: Europe Historic Review for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 37: Europe 16-Year Perspective for Hypercalcemia Treatment by Drug Class - Percentage Breakdown of Value Sales for Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab for the Years 2014, 2024 & 2030
FRANCE
  • Hypercalcemia Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in France for 2024 (E)
  • Table 38: France Recent Past, Current & Future Analysis for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
  • Table 39: France Historic Review for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 40: France 16-Year Perspective for Hypercalcemia Treatment by Drug Class - Percentage Breakdown of Value Sales for Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab for the Years 2014, 2024 & 2030
GERMANY
  • Hypercalcemia Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Germany for 2024 (E)
  • Table 41: Germany Recent Past, Current & Future Analysis for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
  • Table 42: Germany Historic Review for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 43: Germany 16-Year Perspective for Hypercalcemia Treatment by Drug Class - Percentage Breakdown of Value Sales for Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab for the Years 2014, 2024 & 2030
ITALY
  • Table 44: Italy Recent Past, Current & Future Analysis for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
  • Table 45: Italy Historic Review for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 46: Italy 16-Year Perspective for Hypercalcemia Treatment by Drug Class - Percentage Breakdown of Value Sales for Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab for the Years 2014, 2024 & 2030
UNITED KINGDOM
  • Hypercalcemia Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in the United Kingdom for 2024 (E)
  • Table 47: UK Recent Past, Current & Future Analysis for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
  • Table 48: UK Historic Review for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 49: UK 16-Year Perspective for Hypercalcemia Treatment by Drug Class - Percentage Breakdown of Value Sales for Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab for the Years 2014, 2024 & 2030
REST OF EUROPE
  • Table 50: Rest of Europe Recent Past, Current & Future Analysis for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
  • Table 51: Rest of Europe Historic Review for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 52: Rest of Europe 16-Year Perspective for Hypercalcemia Treatment by Drug Class - Percentage Breakdown of Value Sales for Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab for the Years 2014, 2024 & 2030
ASIA-PACIFIC
  • Hypercalcemia Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Asia-Pacific for 2024 (E)
  • Table 53: Asia-Pacific Recent Past, Current & Future Analysis for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
  • Table 54: Asia-Pacific Historic Review for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 55: Asia-Pacific 16-Year Perspective for Hypercalcemia Treatment by Drug Class - Percentage Breakdown of Value Sales for Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab for the Years 2014, 2024 & 2030
REST OF WORLD
  • Table 56: Rest of World Recent Past, Current & Future Analysis for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab - Independent Analysis of Annual Sales in US$ Million for the Years 2023 through 2030 and % CAGR
  • Table 57: Rest of World Historic Review for Hypercalcemia Treatment by Drug Class - Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab Markets - Independent Analysis of Annual Sales in US$ Million for Years 2014 through 2022 and % CAGR
  • Table 58: Rest of World 16-Year Perspective for Hypercalcemia Treatment by Drug Class - Percentage Breakdown of Value Sales for Bisphosphonates, Calcitonin, Glucocorticoids, Calcimimetic Agents and Denusomab for the Years 2014, 2024 & 2030
IV. COMPETITION

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • AbbVie, Inc.
  • Amgen, Inc.
  • DiaSorin SpA
  • Fujirebio Europe NV
  • Kyowa Hakko Kirin Co., Ltd.
  • Merck & Co., Inc.
  • Novartis AG
  • Opko Health, Inc.
  • Rockwell Medical

Table Information