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Sickle Cell Disease Treatment - Global Strategic Business Report

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    Report

  • 182 Pages
  • November 2024
  • Region: Global
  • Global Industry Analysts, Inc
  • ID: 5309831
The global market for Sickle Cell Disease Treatment was estimated at US$2.6 Billion in 2023 and is projected to reach US$8.6 Billion by 2030, growing at a CAGR of 18.7% from 2023 to 2030. This comprehensive report provides an in-depth analysis of market trends, drivers, and forecasts, helping you make informed business decisions.

Global Sickle Cell Disease Treatment Market - Key Trends and Drivers Summarized

Why Is Sickle Cell Disease Treatment Gaining Global Attention?

Sickle cell disease (SCD) treatment is gaining significant global attention due to its rising prevalence and the severe impact it has on the quality of life of patients. Sickle cell disease is a hereditary blood disorder characterized by abnormally shaped red blood cells, which can cause severe pain, frequent infections, and other life-threatening complications. Predominantly affecting people of African, Mediterranean, South Asian, and Middle Eastern descent, SCD is becoming a major public health concern, especially in regions like Sub-Saharan Africa, where the disease burden is particularly high. Efforts to improve early diagnosis, increase awareness, and develop comprehensive care frameworks are driving the demand for effective treatment solutions, including pain management, hydroxyurea therapy, blood transfusions, and bone marrow transplants.

How Are Technological Advancements Revolutionizing Sickle Cell Disease Treatment?

Technological advancements are revolutionizing sickle cell disease treatment by introducing innovative therapies such as gene therapy and CRISPR-based genome editing. These advanced treatments aim to provide a one-time cure by correcting the defective gene responsible for the disease, unlike conventional therapies that primarily focus on symptom management. Several gene therapies, including Lentiglobin, are currently under clinical trials, showing promise in reversing the effects of SCD and reducing the need for regular blood transfusions and pain management. The advent of personalized medicine, which involves tailoring treatment plans based on the genetic makeup of the individual, is further enhancing the effectiveness of these therapies. In addition to gene therapy, other novel approaches such as voxelotor and L-glutamine therapies are expanding the range of available treatment options, providing relief from symptoms and improving patient outcomes.

Which Market Segments Are Leading the Adoption of Sickle Cell Disease Treatment?

Treatment types include pharmacotherapy, blood transfusion, bone marrow transplant, and gene therapy, with pharmacotherapy being the most widely adopted due to its accessibility and affordability. However, gene therapy is expected to grow at the fastest rate due to its potential as a curative treatment. End-users of SCD treatments include hospitals, specialty clinics, and research organizations, with hospitals being the primary adopters due to their role in providing comprehensive care and managing complications associated with the disease. Geographically, North America and Europe are the leading markets for SCD treatment due to advanced healthcare infrastructures, ongoing clinical trials, and regulatory support for orphan drug development. Meanwhile, Africa and the Middle East are emerging as key markets due to the high prevalence of SCD and increasing government initiatives for improved healthcare access.

What Are the Key Drivers of Growth in the Sickle Cell Disease Treatment Market?

The growth in the sickle cell disease treatment market is driven by several factors, including the rising prevalence of sickle cell disease globally, advancements in gene therapy and CRISPR technology, and increasing investment in R&D for targeted therapies and biological drugs. The development of curative therapies, novel drug combinations, and cell-based therapies is driving market adoption among hospitals, specialty clinics, and research organizations. The focus on enhancing early diagnosis, personalized medicine, and patient-centric care models is expanding the market reach among pediatric and adult patients. The growing use of telemedicine and digital health platforms for SCD management, coupled with the demand for affordable and accessible treatment solutions, is creating new opportunities for market growth. Additionally, the increasing collaboration between research institutions, pharmaceutical companies, and non-profit organizations for developing innovative treatments is further supporting market expansion.

Key Insights:

  • Market Growth: Understand the significant growth trajectory of the Blood Transfusion segment, which is expected to reach US$6.5 Billion by 2030 with a CAGR of a 19.3%. The Bone Marrow Transplant segment is also set to grow at 17.5% CAGR over the analysis period.
  • Regional Analysis: Gain insights into the U.S. market, which was estimated at $701.6 Million in 2023, and China, forecasted to grow at an impressive 17.3% CAGR to reach $1.3 Billion by 2030. Discover growth trends in other key regions, including Japan, Canada, Germany, and the Asia-Pacific.

Why You Should Buy This Report:

  • Detailed Market Analysis: Access a thorough analysis of the Global Sickle Cell Disease Treatment Market, covering all major geographic regions and market segments.
  • Competitive Insights: Get an overview of the competitive landscape, including the market presence of major players across different geographies.
  • Future Trends and Drivers: Understand the key trends and drivers shaping the future of the Global Sickle Cell Disease Treatment Market.
  • Actionable Insights: Benefit from actionable insights that can help you identify new revenue opportunities and make strategic business decisions.

Key Questions Answered:

  • How is the Global Sickle Cell Disease Treatment Market expected to evolve by 2030?
  • What are the main drivers and restraints affecting the market?
  • Which market segments will grow the most over the forecast period?
  • How will market shares for different regions and segments change by 2030?
  • Who are the leading players in the market, and what are their prospects?

Report Features:

  • Comprehensive Market Data: Independent analysis of annual sales and market forecasts in US$ Million from 2023 to 2030.
  • In-Depth Regional Analysis: Detailed insights into key markets, including the U.S., China, Japan, Canada, Europe, Asia-Pacific, Latin America, Middle East, and Africa.
  • Company Profiles: Coverage of major players such as Acceleron Pharma, Inc., Alnylam Pharmaceuticals, Inc., Arena Pharmaceuticals, Inc., and more.
  • Complimentary Updates: Receive free report updates for one year to keep you informed of the latest market developments.

Select Competitors (Total 13 Featured):

  • Acceleron Pharma, Inc.
  • Alnylam Pharmaceuticals, Inc.
  • Arena Pharmaceuticals, Inc.
  • AstraZeneca PLC
  • Baxter International, Inc.
  • bluebird bio, Inc.
  • Bristol-Myers Squibb Company
  • Eli Lilly and Company
  • Emmaus Life Sciences, Inc.
  • Global Blood Therapeutics, Inc.
  • Novartis AG
  • Pfizer, Inc.
  • Sangamo Therapeutics, Inc.

Table of Contents

I. METHODOLOGYII. EXECUTIVE SUMMARY
1. MARKET OVERVIEW
  • Influencer Market Insights
  • World Market Trajectories
  • Global Economic Update
  • Sickle Cell Disease Treatment - Global Key Competitors Percentage Market Share in 2024 (E)
  • Competitive Market Presence - Strong/Active/Niche/Trivial for Players Worldwide in 2024 (E)
2. FOCUS ON SELECT PLAYERS
3. MARKET TRENDS & DRIVERS
  • Growing Awareness and Diagnosis of Sickle Cell Disease Expands Addressable Market Opportunity
  • Advancements in Gene Therapy and CRISPR Technology Propel Innovation in Sickle Cell Treatment
  • Rising Prevalence of Sickle Cell Disease in Africa and Middle East Drives Market Demand
  • FDA Approvals and Orphan Drug Designations Strengthen Business Case for Sickle Cell Drugs
  • Challenges Related to High Treatment Costs and Limited Access Pose Market Constraints
  • Focus on Developing Curative Therapies and Novel Drug Combinations Drives Adoption
  • Emergence of Cell-Based Therapies and Bone Marrow Transplants Generates New Market Opportunities
  • Expansion of Public and Private Healthcare Funding Throws Spotlight on Affordable Treatments
  • Emphasis on Developing Pediatric Treatments and Neonatal Screening Programs Drives Market Adoption
  • Growing Pipeline of Promising Drug Candidates in Clinical Trials Enhances Market Competitiveness
  • Advent of Telemedicine and Digital Health Platforms for Sickle Cell Management Expands Market Reach
  • Focus on Personalized Medicine and Patient-Centric Care Models Reinforces Market Growth Potential
4. GLOBAL MARKET PERSPECTIVE
  • Table 1: World Sickle Cell Disease Treatment Market Analysis of Annual Sales in US$ Thousand for Years 2014 through 2030
  • Table 2: World Recent Past, Current & Future Analysis for Sickle Cell Disease Treatment by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • Table 3: World Historic Review for Sickle Cell Disease Treatment by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 4: World 16-Year Perspective for Sickle Cell Disease Treatment by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets for Years 2014, 2024 & 2030
  • Table 5: World Recent Past, Current & Future Analysis for Blood Transfusion by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • Table 6: World Historic Review for Blood Transfusion by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 7: World 16-Year Perspective for Blood Transfusion by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • Table 8: World Recent Past, Current & Future Analysis for Bone Marrow Transplant by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • Table 9: World Historic Review for Bone Marrow Transplant by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 10: World 16-Year Perspective for Bone Marrow Transplant by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • Table 11: World Recent Past, Current & Future Analysis for Pharmacotherapy by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • Table 12: World Historic Review for Pharmacotherapy by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 13: World 16-Year Perspective for Pharmacotherapy by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
III. MARKET ANALYSIS
UNITED STATES
  • Sickle Cell Disease Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in the United States for 2024 (E)
  • Table 14: USA Recent Past, Current & Future Analysis for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • Table 15: USA Historic Review for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 16: USA 16-Year Perspective for Sickle Cell Disease Treatment by Treatment Type - Percentage Breakdown of Value Sales for Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy for the Years 2014, 2024 & 2030
CANADA
  • Table 17: Canada Recent Past, Current & Future Analysis for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • Table 18: Canada Historic Review for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 19: Canada 16-Year Perspective for Sickle Cell Disease Treatment by Treatment Type - Percentage Breakdown of Value Sales for Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy for the Years 2014, 2024 & 2030
JAPAN
  • Sickle Cell Disease Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Japan for 2024 (E)
  • Table 20: Japan Recent Past, Current & Future Analysis for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • Table 21: Japan Historic Review for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 22: Japan 16-Year Perspective for Sickle Cell Disease Treatment by Treatment Type - Percentage Breakdown of Value Sales for Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy for the Years 2014, 2024 & 2030
CHINA
  • Sickle Cell Disease Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in China for 2024 (E)
  • Table 23: China Recent Past, Current & Future Analysis for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • Table 24: China Historic Review for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 25: China 16-Year Perspective for Sickle Cell Disease Treatment by Treatment Type - Percentage Breakdown of Value Sales for Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy for the Years 2014, 2024 & 2030
EUROPE
  • Sickle Cell Disease Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Europe for 2024 (E)
  • Table 26: Europe Recent Past, Current & Future Analysis for Sickle Cell Disease Treatment by Geographic Region - France, Germany, Italy, UK and Rest of Europe Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • Table 27: Europe Historic Review for Sickle Cell Disease Treatment by Geographic Region - France, Germany, Italy, UK and Rest of Europe Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 28: Europe 16-Year Perspective for Sickle Cell Disease Treatment by Geographic Region - Percentage Breakdown of Value Sales for France, Germany, Italy, UK and Rest of Europe Markets for Years 2014, 2024 & 2030
  • Table 29: Europe Recent Past, Current & Future Analysis for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • Table 30: Europe Historic Review for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 31: Europe 16-Year Perspective for Sickle Cell Disease Treatment by Treatment Type - Percentage Breakdown of Value Sales for Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy for the Years 2014, 2024 & 2030
FRANCE
  • Sickle Cell Disease Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in France for 2024 (E)
  • Table 32: France Recent Past, Current & Future Analysis for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • Table 33: France Historic Review for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 34: France 16-Year Perspective for Sickle Cell Disease Treatment by Treatment Type - Percentage Breakdown of Value Sales for Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy for the Years 2014, 2024 & 2030
GERMANY
  • Sickle Cell Disease Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Germany for 2024 (E)
  • Table 35: Germany Recent Past, Current & Future Analysis for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • Table 36: Germany Historic Review for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 37: Germany 16-Year Perspective for Sickle Cell Disease Treatment by Treatment Type - Percentage Breakdown of Value Sales for Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy for the Years 2014, 2024 & 2030
ITALY
  • Table 38: Italy Recent Past, Current & Future Analysis for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • Table 39: Italy Historic Review for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 40: Italy 16-Year Perspective for Sickle Cell Disease Treatment by Treatment Type - Percentage Breakdown of Value Sales for Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy for the Years 2014, 2024 & 2030
UNITED KINGDOM
  • Sickle Cell Disease Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in the United Kingdom for 2024 (E)
  • Table 41: UK Recent Past, Current & Future Analysis for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • Table 42: UK Historic Review for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 43: UK 16-Year Perspective for Sickle Cell Disease Treatment by Treatment Type - Percentage Breakdown of Value Sales for Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy for the Years 2014, 2024 & 2030
REST OF EUROPE
  • Table 44: Rest of Europe Recent Past, Current & Future Analysis for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • Table 45: Rest of Europe Historic Review for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 46: Rest of Europe 16-Year Perspective for Sickle Cell Disease Treatment by Treatment Type - Percentage Breakdown of Value Sales for Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy for the Years 2014, 2024 & 2030
ASIA-PACIFIC
  • Sickle Cell Disease Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Asia-Pacific for 2024 (E)
  • Table 47: Asia-Pacific Recent Past, Current & Future Analysis for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • Table 48: Asia-Pacific Historic Review for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 49: Asia-Pacific 16-Year Perspective for Sickle Cell Disease Treatment by Treatment Type - Percentage Breakdown of Value Sales for Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy for the Years 2014, 2024 & 2030
REST OF WORLD
  • Table 50: Rest of World Recent Past, Current & Future Analysis for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy - Independent Analysis of Annual Sales in US$ Thousand for the Years 2023 through 2030 and % CAGR
  • Table 51: Rest of World Historic Review for Sickle Cell Disease Treatment by Treatment Type - Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 52: Rest of World 16-Year Perspective for Sickle Cell Disease Treatment by Treatment Type - Percentage Breakdown of Value Sales for Blood Transfusion, Bone Marrow Transplant and Pharmacotherapy for the Years 2014, 2024 & 2030
IV. COMPETITION

Companies Mentioned

  • Acceleron Pharma, Inc.
  • Alnylam Pharmaceuticals, Inc.
  • Arena Pharmaceuticals, Inc.
  • AstraZeneca PLC
  • Baxter International, Inc.
  • bluebird bio, Inc.
  • Bristol-Myers Squibb Company
  • Eli Lilly and Company
  • Emmaus Life Sciences, Inc.
  • Global Blood Therapeutics, Inc.
  • Novartis AG
  • Pfizer, Inc.
  • Sangamo Therapeutics, Inc.

Table Information