This report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market’s historic and forecast market growth by geography.
The sickle cell disease treatment market size has grown rapidly in recent years. It will grow from $2.95 billion in 2024 to $3.54 billion in 2025 at a compound annual growth rate (CAGR) of 19.7%. The growth in the historic period can be attributed to disease understanding, blood transfusions, pain management, hydroxyurea therapy.
The sickle cell disease treatment market size is expected to see rapid growth in the next few years. It will grow to $6.8 billion in 2029 at a compound annual growth rate (CAGR) of 17.7%. The growth in the forecast period can be attributed to gene editing and gene therapy, new drug development, telemedicine and remote monitoring, global health initiatives. Major trends in the forecast period include curative therapies, pain management alternatives, global collaborations, patient advocacy and engagement.
The growing need for blood transfusions is expected to propel the expansion of the sickle cell disease treatment market in the foreseeable future. Blood transfusion is a medical procedure involving the transfer of blood or blood products from a donor to a recipient. It plays a crucial role in the treatment of sickle cell disease (SCD) patients by enhancing the blood's oxygen-carrying capacity and reducing the complications associated with vaso-occlusion. For example, in December 2022, gov.UK reported that the UK witnessed an increase in blood donations in 2021, with 1.7 million donations made across the country. Moreover, in January 2022, according to Mid-Atlantic Long-Term Care, the United States requires approximately 29,000 units of red blood cells, 5,000 units of platelets, and 6,500 units of plasma daily. Therefore, the growing demand for blood transfusions is a driving force behind the growth of the sickle cell disease treatment market.
The increasing number of blood and bone marrow transplants is expected to drive the growth of the sickle cell disease treatment market in the coming years. A blood and bone marrow transplant involves replacing unhealthy blood-forming cells with healthy ones to treat conditions like sickle cell disease. This procedure can involve infusing healthy bone marrow cells either from the patient's own body (autologous transplant) or from a donor (allogeneic transplant). For example, in June 2024, the National Transplant Organization (ONT) reported that Spain added 23,686 donors to its Bone Marrow Donor Registry in 2023, an 8% increase from 2022. The country also achieved a record 3,717 hematopoietic stem cell transplants, translating to 77.4 transplants per million population. As a result, the rising prevalence of blood and bone marrow transplants is expected to significantly boost the sickle cell disease treatment market.
Leading companies in the sickle cell disease (SCD) treatment market are focusing on developing new oral suspension drugs to improve patient compliance, enhance drug efficacy, and provide more convenient treatment options, particularly for pediatric and elderly patients. Oral suspension drugs are liquid medications with solid particles suspended in a liquid, designed to make it easier for patients to swallow, especially children or those who have difficulty with pills. For example, in March 2024, Akums Drugs and Pharmaceuticals Ltd., an India-based pharmaceutical manufacturing company, launched a room temperature-stable oral suspension of Hydroxyurea. This affordable SCD treatment is designed to increase accessibility in India, priced at less than 1% of imported alternatives. It offers precise dosing with oral syringes, providing a solution for patients of all ages without the need for cold storage.
In October 2022, Pfizer Inc., a pharmaceutical corporation headquartered in the United States, acquired Global Blood Therapeutics Inc. for $5.4 billion. This acquisition provides Pfizer with access to a premier sickle cell disease portfolio and pipeline, addressing the critical needs of an underserved patient population. Global Blood Therapeutics Inc. is a biopharmaceutical company based in the United States, specializing in the development and commercialization of therapies for individuals with sickle cell disease (SCD).
Major companies operating in the sickle cell disease treatment market are Sun Pharmaceutical Industries Ltd., Pfizer Inc., Johnson & Johnson Private Limited, Merck & Co Inc., Novartis AG, Sanofi S.A., Bristol-Myers Squibb Company, AstraZeneca PLC, Eli Lilly and Company, Gilead Sciences Inc., Amgen Inc., Baxter International Inc., Teva Pharmaceutical Industries Ltd., Vertex Pharmaceuticals Incorporated, Alnylam Pharmaceuticals Inc., Ionis Pharmaceuticals Inc., Silver Lake Research Corporation0.45, Global Blood Therapeutics Inc., Acceleron Pharma Inc., Sangamo Therapeutics Inc., Medunik USA Inc., Zydus Cadila Healthcare Ltd., Graphite Bio Inc., Addmedica, Emmaus Medical Inc., Bluebird bio Inc., CRISPR Therapeutics AG, GlycoMimetics Inc., Arena Pharmaceuticals Inc., Mast Therapeutics Inc.
North America was the largest region in the sickle cell disease treatment market in 2024. The regions covered in sickle cell disease treatment report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa. The countries covered in the sickle cell disease treatment market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The sickle cell disease treatment market consists of revenues earned by entities by providing services such as oxygen therapy, pulmonary hypertension management and pain management. The market value includes the value of related goods sold by the service provider or included within the service offering. The sickle cell disease treatment market also includes sales of hydroxyurea, L-glutamine and voxlelotor. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
Sickle cell disease (SCD), also referred to as sickle cell anemia, is a genetic disorder that impacts hemoglobin, a protein found in red blood cells. Individuals with sickle cell disease produce defective hemoglobin, known as hemoglobin S (HbS), due to a mutation in the hemoglobin gene. Treatment for sickle cell disease aims to alleviate blockages, improve blood flow, and repair damaged tissues.
The primary modalities for treating sickle cell disease include blood transfusion, pharmacotherapy, and bone marrow transplant. A blood transfusion involves the transfer of blood or blood products from a donor to a recipient. Sickle cell disease encompasses various types, such as sickle cell anemia, hemoglobin sickle C disease (HbSC), and others, with treatment administered through oral and parenteral routes. End users of these treatments include hospitals, specialty clinics, and other healthcare facilities.
The sickle cell disease treatment market research report is one of a series of new reports that provides sickle cell disease treatment market statistics, including sickle cell disease treatment industry global market size, regional shares, competitors with a sickle cell disease treatment market share, detailed sickle cell disease treatment market segments, market trends and opportunities and any further data you may need to thrive in the sickle cell disease treatment industry. This sickle cell disease treatment market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
This product will be delivered within 3-5 business days.
The sickle cell disease treatment market size has grown rapidly in recent years. It will grow from $2.95 billion in 2024 to $3.54 billion in 2025 at a compound annual growth rate (CAGR) of 19.7%. The growth in the historic period can be attributed to disease understanding, blood transfusions, pain management, hydroxyurea therapy.
The sickle cell disease treatment market size is expected to see rapid growth in the next few years. It will grow to $6.8 billion in 2029 at a compound annual growth rate (CAGR) of 17.7%. The growth in the forecast period can be attributed to gene editing and gene therapy, new drug development, telemedicine and remote monitoring, global health initiatives. Major trends in the forecast period include curative therapies, pain management alternatives, global collaborations, patient advocacy and engagement.
The growing need for blood transfusions is expected to propel the expansion of the sickle cell disease treatment market in the foreseeable future. Blood transfusion is a medical procedure involving the transfer of blood or blood products from a donor to a recipient. It plays a crucial role in the treatment of sickle cell disease (SCD) patients by enhancing the blood's oxygen-carrying capacity and reducing the complications associated with vaso-occlusion. For example, in December 2022, gov.UK reported that the UK witnessed an increase in blood donations in 2021, with 1.7 million donations made across the country. Moreover, in January 2022, according to Mid-Atlantic Long-Term Care, the United States requires approximately 29,000 units of red blood cells, 5,000 units of platelets, and 6,500 units of plasma daily. Therefore, the growing demand for blood transfusions is a driving force behind the growth of the sickle cell disease treatment market.
The increasing number of blood and bone marrow transplants is expected to drive the growth of the sickle cell disease treatment market in the coming years. A blood and bone marrow transplant involves replacing unhealthy blood-forming cells with healthy ones to treat conditions like sickle cell disease. This procedure can involve infusing healthy bone marrow cells either from the patient's own body (autologous transplant) or from a donor (allogeneic transplant). For example, in June 2024, the National Transplant Organization (ONT) reported that Spain added 23,686 donors to its Bone Marrow Donor Registry in 2023, an 8% increase from 2022. The country also achieved a record 3,717 hematopoietic stem cell transplants, translating to 77.4 transplants per million population. As a result, the rising prevalence of blood and bone marrow transplants is expected to significantly boost the sickle cell disease treatment market.
Leading companies in the sickle cell disease (SCD) treatment market are focusing on developing new oral suspension drugs to improve patient compliance, enhance drug efficacy, and provide more convenient treatment options, particularly for pediatric and elderly patients. Oral suspension drugs are liquid medications with solid particles suspended in a liquid, designed to make it easier for patients to swallow, especially children or those who have difficulty with pills. For example, in March 2024, Akums Drugs and Pharmaceuticals Ltd., an India-based pharmaceutical manufacturing company, launched a room temperature-stable oral suspension of Hydroxyurea. This affordable SCD treatment is designed to increase accessibility in India, priced at less than 1% of imported alternatives. It offers precise dosing with oral syringes, providing a solution for patients of all ages without the need for cold storage.
In October 2022, Pfizer Inc., a pharmaceutical corporation headquartered in the United States, acquired Global Blood Therapeutics Inc. for $5.4 billion. This acquisition provides Pfizer with access to a premier sickle cell disease portfolio and pipeline, addressing the critical needs of an underserved patient population. Global Blood Therapeutics Inc. is a biopharmaceutical company based in the United States, specializing in the development and commercialization of therapies for individuals with sickle cell disease (SCD).
Major companies operating in the sickle cell disease treatment market are Sun Pharmaceutical Industries Ltd., Pfizer Inc., Johnson & Johnson Private Limited, Merck & Co Inc., Novartis AG, Sanofi S.A., Bristol-Myers Squibb Company, AstraZeneca PLC, Eli Lilly and Company, Gilead Sciences Inc., Amgen Inc., Baxter International Inc., Teva Pharmaceutical Industries Ltd., Vertex Pharmaceuticals Incorporated, Alnylam Pharmaceuticals Inc., Ionis Pharmaceuticals Inc., Silver Lake Research Corporation0.45, Global Blood Therapeutics Inc., Acceleron Pharma Inc., Sangamo Therapeutics Inc., Medunik USA Inc., Zydus Cadila Healthcare Ltd., Graphite Bio Inc., Addmedica, Emmaus Medical Inc., Bluebird bio Inc., CRISPR Therapeutics AG, GlycoMimetics Inc., Arena Pharmaceuticals Inc., Mast Therapeutics Inc.
North America was the largest region in the sickle cell disease treatment market in 2024. The regions covered in sickle cell disease treatment report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa. The countries covered in the sickle cell disease treatment market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The sickle cell disease treatment market consists of revenues earned by entities by providing services such as oxygen therapy, pulmonary hypertension management and pain management. The market value includes the value of related goods sold by the service provider or included within the service offering. The sickle cell disease treatment market also includes sales of hydroxyurea, L-glutamine and voxlelotor. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
Sickle cell disease (SCD), also referred to as sickle cell anemia, is a genetic disorder that impacts hemoglobin, a protein found in red blood cells. Individuals with sickle cell disease produce defective hemoglobin, known as hemoglobin S (HbS), due to a mutation in the hemoglobin gene. Treatment for sickle cell disease aims to alleviate blockages, improve blood flow, and repair damaged tissues.
The primary modalities for treating sickle cell disease include blood transfusion, pharmacotherapy, and bone marrow transplant. A blood transfusion involves the transfer of blood or blood products from a donor to a recipient. Sickle cell disease encompasses various types, such as sickle cell anemia, hemoglobin sickle C disease (HbSC), and others, with treatment administered through oral and parenteral routes. End users of these treatments include hospitals, specialty clinics, and other healthcare facilities.
The sickle cell disease treatment market research report is one of a series of new reports that provides sickle cell disease treatment market statistics, including sickle cell disease treatment industry global market size, regional shares, competitors with a sickle cell disease treatment market share, detailed sickle cell disease treatment market segments, market trends and opportunities and any further data you may need to thrive in the sickle cell disease treatment industry. This sickle cell disease treatment market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
This product will be delivered within 3-5 business days.
Table of Contents
1. Executive Summary2. Sickle Cell Disease Treatment Market Characteristics3. Sickle Cell Disease Treatment Market Trends and Strategies4. Sickle Cell Disease Treatment Market - Macro Economic Scenario Including the Impact of Interest Rates, Inflation, Geopolitics, Covid and Recovery on the Market32. Global Sickle Cell Disease Treatment Market Competitive Benchmarking and Dashboard33. Key Mergers and Acquisitions in the Sickle Cell Disease Treatment Market34. Recent Developments in the Sickle Cell Disease Treatment Market
5. Global Sickle Cell Disease Treatment Growth Analysis and Strategic Analysis Framework
6. Sickle Cell Disease Treatment Market Segmentation
7. Sickle Cell Disease Treatment Market Regional and Country Analysis
8. Asia-Pacific Sickle Cell Disease Treatment Market
9. China Sickle Cell Disease Treatment Market
10. India Sickle Cell Disease Treatment Market
11. Japan Sickle Cell Disease Treatment Market
12. Australia Sickle Cell Disease Treatment Market
13. Indonesia Sickle Cell Disease Treatment Market
14. South Korea Sickle Cell Disease Treatment Market
15. Western Europe Sickle Cell Disease Treatment Market
16. UK Sickle Cell Disease Treatment Market
17. Germany Sickle Cell Disease Treatment Market
18. France Sickle Cell Disease Treatment Market
19. Italy Sickle Cell Disease Treatment Market
20. Spain Sickle Cell Disease Treatment Market
21. Eastern Europe Sickle Cell Disease Treatment Market
22. Russia Sickle Cell Disease Treatment Market
23. North America Sickle Cell Disease Treatment Market
24. USA Sickle Cell Disease Treatment Market
25. Canada Sickle Cell Disease Treatment Market
26. South America Sickle Cell Disease Treatment Market
27. Brazil Sickle Cell Disease Treatment Market
28. Middle East Sickle Cell Disease Treatment Market
29. Africa Sickle Cell Disease Treatment Market
30. Sickle Cell Disease Treatment Market Competitive Landscape and Company Profiles
31. Sickle Cell Disease Treatment Market Other Major and Innovative Companies
35. Sickle Cell Disease Treatment Market High Potential Countries, Segments and Strategies
36. Appendix
Executive Summary
Sickle Cell Disease Treatment Global Market Report 2025 provides strategists, marketers and senior management with the critical information they need to assess the market.This report focuses on sickle cell disease treatment market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
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Description
Where is the largest and fastest growing market for sickle cell disease treatment? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The sickle cell disease treatment market global report answers all these questions and many more.The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market’s historic and forecast market growth by geography.
- The market characteristics section of the report defines and explains the market.
- The market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
- The forecasts are made after considering the major factors currently impacting the market. These include:
- The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.
- Market segmentations break down the market into sub markets.
- The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth. It covers the growth trajectory of COVID-19 for all regions, key developed countries and major emerging markets.
- The competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
- The trends and strategies section analyses the shape of the market as it emerges from the crisis and suggests how companies can grow as the market recovers.
Scope
Markets Covered:
1) By Treatment Modality: Blood Transfusion; Pharmacotherapy; Bone Marrow Transplant2) By Disease Type: Sickle Cell Anemia; Hemoglobin Sickle C Disease (HbSC); Other Disease Types
3) By Route Of Administration: Oral; Parenteral
4) By End-User: Hospitals; Specialty Clinics; Other End-Users
Subsegments:
1) By Blood Transfusion: Regular Blood Transfusion; Exchange Transfusion2) By Pharmacotherapy: Hydroxyurea; L-Glutamine; Voxelotor; Crizanlizumab
3) By Bone Marrow Transplant: Allogeneic Transplant; Autologous Transplant
Key Companies Mentioned: Sun Pharmaceutical Industries Ltd.; Pfizer Inc.; Johnson & Johnson Private Limited; Merck & Co Inc.; Novartis AG
Countries: Australia; Brazil; China; France; Germany; India; Indonesia; Japan; Russia; South Korea; UK; USA; Canada; Italy; Spain
Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
Time Series: Five years historic and ten years forecast.
Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita.
Data Segmentation: Country and regional historic and forecast data, market share of competitors, market segments.
Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.
Delivery Format: PDF, Word and Excel Data Dashboard.
Companies Mentioned
Some of the major companies featured in this Sickle Cell Disease Treatment market report include:- Sun Pharmaceutical Industries Ltd.
- Pfizer Inc.
- Johnson & Johnson Private Limited
- Merck & Co Inc.
- Novartis AG
- Sanofi S.A.
- Bristol-Myers Squibb Company
- AstraZeneca plc
- Eli Lilly and Company
- Gilead Sciences Inc.
- Amgen Inc.
- Baxter International Inc.
- Teva Pharmaceutical Industries Ltd.
- Vertex Pharmaceuticals Incorporated
- Alnylam Pharmaceuticals Inc.
- Ionis Pharmaceuticals Inc.
- Silver Lake Research Corporation0.45
- Global Blood Therapeutics Inc.
- Acceleron Pharma Inc.
- Sangamo Therapeutics Inc.
- Medunik USA Inc.
- Zydus Cadila Healthcare Ltd.
- Graphite Bio Inc.
- Addmedica
- Emmaus Medical Inc.
- Bluebird bio Inc.
- CRISPR Therapeutics AG
- GlycoMimetics Inc.
- Arena Pharmaceuticals Inc.
- Mast Therapeutics Inc.
Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 200 |
| Published | March 2025 |
| Forecast Period | 2025 - 2029 |
| Estimated Market Value ( USD | $ 3.54 Billion |
| Forecasted Market Value ( USD | $ 6.8 Billion |
| Compound Annual Growth Rate | 17.7% |
| Regions Covered | Global |
| No. of Companies Mentioned | 31 |
