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Alpha 1 Antitrypsin Deficiency Treatment - Global Strategic Business Report

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    Report

  • 196 Pages
  • October 2024
  • Region: Global
  • Global Industry Analysts, Inc
  • ID: 5309866
The global market for Alpha 1 Antitrypsin Deficiency Treatment was estimated at US$2.3 Billion in 2023 and is projected to reach US$4.2 Billion by 2030, growing at a CAGR of 9.0% from 2023 to 2030. This comprehensive report provides an in-depth analysis of market trends, drivers, and forecasts, helping you make informed business decisions.

What Is Alpha 1 Antitrypsin Deficiency and Why Is It Important?

Alpha 1 Antitrypsin Deficiency (AATD) is a genetic disorder that affects the lungs and liver, caused by insufficient levels of the protein alpha 1 antitrypsin (AAT), which protects tissues from enzyme damage. The deficiency can lead to chronic obstructive pulmonary disease (COPD), emphysema, and liver diseases like cirrhosis. AATD is underdiagnosed, and many patients suffer from symptoms for years before receiving appropriate treatment. Managing the condition often requires augmentation therapy, where patients are given purified AAT to reduce lung damage and prevent further deterioration.

What Recent Advancements Are Improving Alpha 1 Antitrypsin Deficiency Treatments?

Recent advancements in the treatment of Alpha 1 Antitrypsin Deficiency include the development of new augmentation therapies and research into gene therapies aimed at correcting the underlying genetic cause. Augmentation therapy, which involves intravenous administration of purified AAT derived from human plasma, remains the primary treatment option for AATD. However, researchers are now focusing on more advanced therapeutic approaches such as RNA-based therapies, which aim to correct the faulty gene responsible for AATD. These developments are creating more effective and long-term solutions for patients, potentially reducing the need for lifelong augmentation therapy.

How Is Awareness and Diagnosis Impacting AATD Treatment Trends?

One of the key challenges in treating Alpha 1 Antitrypsin Deficiency is the high rate of underdiagnosis. Increased awareness campaigns by healthcare organizations and patient advocacy groups are gradually improving diagnosis rates, leading to earlier intervention and better outcomes for patients. Genetic testing has also become more widely available, allowing individuals with a family history of AATD to be screened and diagnosed earlier. As awareness of AATD grows, more patients are gaining access to life-saving treatments, particularly in developed healthcare markets.

What Factors Are Driving the Growth of the Alpha 1 Antitrypsin Deficiency Treatment Market?

The growth in the Alpha 1 Antitrypsin Deficiency treatment market is driven by several factors, including advancements in gene and augmentation therapies, improved diagnosis rates, and increasing awareness of the condition. Innovations in augmentation therapy and research into genetic correction methods are making treatments more effective and accessible. The growing availability of genetic testing is also helping in early detection and treatment, significantly improving patient outcomes. Moreover, patient advocacy and education campaigns are raising awareness about the disorder, prompting earlier intervention and driving demand for AATD therapies.

Key Insights:

  • Market Growth: Understand the significant growth trajectory of the Augmentation Therapy segment, which is expected to reach US$2.0 Billion by 2030 with a CAGR of a 9.7%. The Bronchodilator segment is also set to grow at 9.4% CAGR over the analysis period.
  • Regional Analysis: Gain insights into the U.S. market, which was valued at $638.8 Million in 2023, and China, forecasted to grow at an impressive 8.2% CAGR to reach $635.0 Million by 2030. Discover growth trends in other key regions, including Japan, Canada, Germany, and the Asia-Pacific.

Why You Should Buy This Report:

  • Detailed Market Analysis: Access a thorough analysis of the Global Alpha 1 Antitrypsin Deficiency Treatment Market, covering all major geographic regions and market segments.
  • Competitive Insights: Get an overview of the competitive landscape, including the market presence of major players across different geographies.
  • Future Trends and Drivers: Understand the key trends and drivers shaping the future of the Global Alpha 1 Antitrypsin Deficiency Treatment Market.
  • Actionable Insights: Benefit from actionable insights that can help you identify new revenue opportunities and make strategic business decisions.

Key Questions Answered:

  • How is the Global Alpha 1 Antitrypsin Deficiency Treatment Market expected to evolve by 2030?
  • What are the main drivers and restraints affecting the market?
  • Which market segments will grow the most over the forecast period?
  • How will market shares for different regions and segments change by 2030?
  • Who are the leading players in the market, and what are their prospects?

Report Features:

  • Comprehensive Market Data: Independent analysis of annual sales and market forecasts in US$ Million from 2023 to 2030.
  • In-Depth Regional Analysis: Detailed insights into key markets, including the U.S., China, Japan, Canada, Europe, Asia-Pacific, Latin America, Middle East, and Africa.
  • Company Profiles: Coverage of major players such as Abeona Therapeutics Inc., Applied Genetic Technologies Corporation, Arrowhead Pharmaceuticals Inc., and more.
  • Complimentary Updates: Receive free report updates for one year to keep you informed of the latest market developments.

Select Competitors (Total 46 Featured):

  • Abeona Therapeutics Inc.
  • Applied Genetic Technologies Corporation
  • Arrowhead Pharmaceuticals Inc.
  • AstraZeneca PLC
  • Baxter International, Inc.
  • Biogen, Inc.
  • Boehringer Ingelheim International GmbH
  • Chiesi Farmaceutici SpA
  • CSL Behring
  • Curaxys
  • GlaxoSmithKline PLC
  • Grifols International SA
  • Kamada Ltd.
  • Pfizer, Inc.
  • ProBioGen AG
  • ProMetic Life Sciences, Inc.
  • Shire PLC
  • Teva Pharmaceutical Industries Ltd.

Table of Contents

I. METHODOLOGYII. EXECUTIVE SUMMARY
1. MARKET OVERVIEW
  • Influencer Market Insights
  • World Market Trajectories
  • Impact of COVID-19 and a Looming Global Recession
  • Alpha 1 Antitrypsin Deficiency Treatment - Global Key Competitors Percentage Market Share in 2024 (E)
  • Competitive Market Presence - Strong/Active/Niche/Trivial for Players Worldwide in 2024 (E)
2. FOCUS ON SELECT PLAYERS
3. MARKET TRENDS & DRIVERS
  • Rising Awareness of Alpha 1 Antitrypsin Deficiency Driving Early Diagnosis and Treatment
  • Growing Adoption of Augmentation Therapy for Alpha 1 Antitrypsin Deficiency
  • Increased Research into Gene Therapy Solutions for Long-term Treatment
  • Expansion of Plasma-derived Products for Alpha 1 Antitrypsin Deficiency
  • Advances in Recombinant Alpha 1 Antitrypsin Products for Improved Efficacy
  • New Clinical Trials Exploring Novel Therapeutic Approaches
  • Rising Demand for Home-based and Self-administered Treatments
  • Growing Investment in Personalized Medicine for Alpha 1 Antitrypsin Deficiency
  • Rising Prevalence of Alpha 1 Antitrypsin Deficiency in Undiagnosed Populations
  • Expansion of Treatment Options to Address Respiratory and Liver Complications
4. GLOBAL MARKET PERSPECTIVE
  • Table 1: World Alpha 1 Antitrypsin Deficiency Treatment Market Analysis of Annual Sales in US$ Thousand for Years 2014 through 2030
  • Table 2: World Recent Past, Current & Future Analysis for Alpha 1 Antitrypsin Deficiency Treatment by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • Table 3: World Historic Review for Alpha 1 Antitrypsin Deficiency Treatment by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 4: World 16-Year Perspective for Alpha 1 Antitrypsin Deficiency Treatment by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets for Years 2014, 2024 & 2030
  • Table 5: World Recent Past, Current & Future Analysis for Augmentation Therapy by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • Table 6: World Historic Review for Augmentation Therapy by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 7: World 16-Year Perspective for Augmentation Therapy by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • Table 8: World Recent Past, Current & Future Analysis for Bronchodilator by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • Table 9: World Historic Review for Bronchodilator by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 10: World 16-Year Perspective for Bronchodilator by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • Table 11: World Recent Past, Current & Future Analysis for Corticosteroids by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • Table 12: World Historic Review for Corticosteroids by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 13: World 16-Year Perspective for Corticosteroids by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • Table 14: World Recent Past, Current & Future Analysis for Oxygen Therapy by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • Table 15: World Historic Review for Oxygen Therapy by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 16: World 16-Year Perspective for Oxygen Therapy by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • Table 17: World Recent Past, Current & Future Analysis for Other Treatments by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • Table 18: World Historic Review for Other Treatments by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 19: World 16-Year Perspective for Other Treatments by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • Table 20: World Recent Past, Current & Future Analysis for Specialty Clinics by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • Table 21: World Historic Review for Specialty Clinics by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 22: World 16-Year Perspective for Specialty Clinics by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • Table 23: World Recent Past, Current & Future Analysis for Hospitals by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • Table 24: World Historic Review for Hospitals by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 25: World 16-Year Perspective for Hospitals by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • Table 26: World Recent Past, Current & Future Analysis for Pharmacies by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • Table 27: World Historic Review for Pharmacies by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 28: World 16-Year Perspective for Pharmacies by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • Table 29: World Recent Past, Current & Future Analysis for Parenteral by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • Table 30: World Historic Review for Parenteral by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 31: World 16-Year Perspective for Parenteral by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • Table 32: World Recent Past, Current & Future Analysis for Inhalation by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • Table 33: World Historic Review for Inhalation by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 34: World 16-Year Perspective for Inhalation by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
  • Table 35: World Recent Past, Current & Future Analysis for Oral by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2023 through 2030 and % CAGR
  • Table 36: World Historic Review for Oral by Geographic Region - USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World Markets - Independent Analysis of Annual Sales in US$ Thousand for Years 2014 through 2022 and % CAGR
  • Table 37: World 16-Year Perspective for Oral by Geographic Region - Percentage Breakdown of Value Sales for USA, Canada, Japan, China, Europe, Asia-Pacific and Rest of World for Years 2014, 2024 & 2030
III. MARKET ANALYSIS
UNITED STATES
  • Alpha 1 Antitrypsin Deficiency Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in the United States for 2024 (E)
CANADA
JAPAN
  • Alpha 1 Antitrypsin Deficiency Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Japan for 2024 (E)
CHINA
  • Alpha 1 Antitrypsin Deficiency Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in China for 2024 (E)
EUROPE
  • Alpha 1 Antitrypsin Deficiency Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Europe for 2024 (E)
FRANCE
  • Alpha 1 Antitrypsin Deficiency Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in France for 2024 (E)
GERMANY
  • Alpha 1 Antitrypsin Deficiency Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Germany for 2024 (E)
ITALY
UNITED KINGDOM
  • Alpha 1 Antitrypsin Deficiency Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in the United Kingdom for 2024 (E)
REST OF EUROPE
ASIA-PACIFIC
  • Alpha 1 Antitrypsin Deficiency Treatment Market Presence - Strong/Active/Niche/Trivial - Key Competitors in Asia-Pacific for 2024 (E)
REST OF WORLDIV. COMPETITION

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Abeona Therapeutics Inc.
  • Applied Genetic Technologies Corporation
  • Arrowhead Pharmaceuticals Inc.
  • AstraZeneca PLC
  • Baxter International, Inc.
  • Biogen, Inc.
  • Boehringer Ingelheim International GmbH
  • Chiesi Farmaceutici SpA
  • CSL Behring
  • Curaxys
  • GlaxoSmithKline PLC
  • Grifols International SA
  • Kamada Ltd.
  • Pfizer, Inc.
  • ProBioGen AG
  • ProMetic Life Sciences, Inc.
  • Shire PLC
  • Teva Pharmaceutical Industries Ltd.

Table Information