Antidotes to Toxins and Drugs: From Natural Sources to Drug Discovery in Toxicology presents recent advances in the discovery of natural antidotes to toxins, drug intoxications and overdoses in pharmacology, drug discovery and toxicology. The text provides detailed information about toxins and their natural antidotes, along with the identification and screening of antidotes for drug intoxications and overdoses. Written by a global team of experts, it describes the potential uses of natural products in toxicology and their applications in medicine and in the pharmaceutical sciences. This book will be a key resource for drug developers, medicinal chemists and toxicologists, among others.Sections shine a particular focus on mechanisms of action, various principles in pharmacokinetics and pharmacodynamics terms, and possible sources and synthesis techniques for these phytochemicals.
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Table of Contents
1. Toxins of Natural Products2. Antidotes to Bacterial Toxins/Toxic Substances from BacteriaIn Vivo Bacterial Toxins, Toxic Shock Syndrome, Bacterial Toxins Produced Outside the Body3. Antidotes to Mycotoxins, Aflatoxins, Other Mycotoxins, Mushroom Toxins4. Antidotes to Toxins from Protozoa5. Antidotes to Toxic Substances from PlantsNerve Toxins from Plants e.g. Pyrethrins and Pyrethroids; Internal Organ Plant Toxins; Eye and Skin Irritants; Allergens; Mineral Accumulators; Toxic Algae6. Antidotes to Insect Toxins, Bee Venom; Wasp and Hornet Venoms; Toxicities of Insect Venoms7. Antidotes to Spider ToxinsBrown Recluse Spiders; Widow Spiders; Other Spiders8. Antidotes to Reptile ToxinsChemical Composition of Snake Venoms; Toxic Effects of Snake Venom9. Antidotes to Nonreptile Animal Toxins10. Antidotes to Drug Intoxications or Drug OverdosesAuthors
Mihnea-Alexandru Gaman Specialist, Clinical Haemotology, Department of Haemotology, Centre of Haemotology and Bone Marrow Transplantation, Fundeni Clinical Institute, Bucharest, Romania.Mihnea-Alexandru Gaman received his MD at the Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. Dr. Gaman is currently specializing in clinical hematology at the Department of Hematology, Centre of Hematology and Bone Marrow Transplantation, Fundeni Clinical Institute, Bucharest, Romania. He has published more than 100 papers in international impact factor journals, as well as served as editor and author for international and national books/book chapters. In addition, Dr. Gaman also serves as Scientific Editor, Associate Editor, Editorial Board Member and Peer-Reviewer for several international and national journals. His main fields of interest include hematology, molecular biology, oncology, internal medicine, medical education, fundamental sciences, and translational/interdisciplinary medicine.
Chukwuebuka Egbuna Chukwuemeka Odumegwu Ojukwu University, Anambra State, Nigeria.Chukwuebuka Egbuna (PhD) is a chartered chemist and academic researcher. He is a member of the Institute of Chartered Chemists of Nigeria (ICCON), the Nigerian Society of Biochemistry and Molecular Biology (NSBMB), and the Royal Society of Chemistry (RSC) (United Kingdom). Dr. Egbuna is the founder and editor of the Elsevier book series on Drug Discovery Update. The series includes books, monographs, and edited collections from all areas of drug discovery including emerging therapeutic claims for the treatment of diseases. He has published research articles in many international journals of repute and is ranked among the top 500 Nigerian scientists in SciVal/SCOPUS. He has edited more than 25 books with Elsevier, Springer, Wiley, and Taylor & Francis. His most recent book is the three volume Coronavirus Drug Discovery, published by Elsevier. Dr. Egbuna is the founder and the publishing director of IPS Intelligentsia Publishing Services.
