Nanomedical Drug Delivery for Neurodegenerative Diseases opens the door for promising approaches and advances in the diagnosis and treatment of various neurodegenerative diseases. The contents of the book comprise all the aspects related to the design, synthesis, and application of different nanodrug delivery systems in the treatment of neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease, Huntington's disease, and motor neuron diseases. This book explores how nanoparticulate drug carriers can improve therapeutic efficacy by selecting a suitable design strategy. Nanomedical Drug Delivery for Neurodegenerative Diseases is a valuable resource for graduates, clinical researchers, and other scientists working to minimize the challenges to deliver the drugs and genes in a more efficient and targeted manner for the treatment of neurodegenerative diseases.
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Table of Contents
1. Aetiology and pathophysiology of neurodegenerative disorders Rakesh K. Sahoo, Tanisha Gupta, Smilly, Vinay Kumar, Sarita Rani, and Umesh Gupta 2. Targeted nanoparticles for the treatment of Alzheimer's disease Davood Gheidari and Mohammad Bayat 3. Neurodegenerative disorders due to inhalation of various small particles Krishna Jadhav, Raghuraj, Eupa Ray, Kalpesh Vaghasiya, and Rahul Kumar Verma 4. Lipid nanocarrier-based drug delivery for the treatment of brain-related disorders Satish Shilpi, Ashish Jain, Sonal Dixit, Gaurav Saraogi, Awesh Kumar Yadav, and Sanjay K. Jain 5. Nanomedical drug delivery for neurodegenerative disease Navjot Kaur, Vanktesh Kumar, Thatikayala Mahender, Indrani Maji, Shrusti Mahajan, Pankaj Kumar Singh, and Sanjeev Kumar Sahu 6. siRNA polymer conjugates for the delivery of RNAi therapeutics for the treatment of Parkinson's disease Priya Singh, Nidhi Mishra, Neelu Singh, Alka Sonkar, Samipta Singh, Raquibun Nisha, Priyanka Maurya, Ravi Raj Pal, and Shubhini A. Saraf 7. Potential of nanoparticles as novel therapeutics against Alzheimer's Disease Rewati Raman Ujjwal, Sandeep Kr Maharana, Mayank Handa, and S.T.V. Sai Krishna 8. Recent trends of extracellular vesticles for therapeutic intervention of brain-related diseases Mayank Handa, Reddy Gayathri Aparnasai, Nikita Panicker, Sanjiv Singh, and Munindra Ruwali 9. Mitochondria-targeted drug delivery systems for the effective treatment of neurodegenerative disorders Vaishali Khare, Surbhi Gupta, Preeti Bisht, and Debapriya Garabadu 10. Recent trends of theranostic applications of nanoparticles in neurodegenerative disorders Sarjana Raikwar and Sanjay K. Jain 11. Role of nanoparticles in neurotoxicity Rishi Paliwal, Kunjbihari Sulakhiya, Shivani Rai Paliwal, Vijal Singh, Rameshroo Kenwat, and Debashish Paramanik 12. Metal nanoparticles for neurodegenerative diseases Shagufta Haque and Chitta Ranjan Patra 13. Nano-based phytodrug delivery systems for the management of neurodegenerative disorders M.S. Sudheesh and R.S. Pawar 14. Nanoparticle-mediated delivery of AChE inhibitors for the treatment of Alzheimer's disease Pallav Namdeo, Jinu Mathew, and Ashish Garg 15. Nanomaterial-bsed drug delivery systems as tools for targeted therapy of neurodegenerative diseases Rahul Shukla, Vaibhavi Srivastava, Aakriti Sethi, and Munindra Ruwali 16. Sample preparation techniques for quantitative analysis in brain pharmacokinetics: Application to neurodegenerative diseases Pramod Kumar, Waibiangki Lyngdoh, Banwarilal, and Amit Alexander
Authors
Awesh K. Yadav Assistant Professor, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research Raebareli, A Transit Campus at Bijnor-Sesendi Road, Sarojini Nagar, Near CRPF Base Camp, Lucknow, Uttar Pradesh, India.Dr. Awesh K. Yadav has received his B.Pharm, M.Pharm, and PhD from Dr. Hari Singh Gour University Sagar (MP). He is currently working as Assistant Professor in the Department of Pharmaceutics at the National Institute of Pharmaceutical Education and Research Raebareli, India. He has more than 15 years of teaching and industrial experience in various institutes and industries. He has written dozens of quality research publications in journals of national and international repute. He has also published four books and seven book chapters. He has been awarded the best citation award for his publication in the International Journal of Pharmaceutics in 2005. Dr. Yadav's current research interest includes targeted and controlled novel drug delivery systems for the delivery of various bioactives such as anticancer drugs, anti-Alzheimer's drugs, anti-Parkinson drugs, anti-malarial drugs, sun-screening agents, etc.
Rahul Shukla Assistant Professor, Department of Pharmeceutics, National Institute of Pharmaceutical Education and Research, Raebareli, Uttar Pradesh, India. Dr. Rahul Shukla is currently working as an Assistant Professor (Contract) at Department of Pharmaceutics, NIPER Raebareli, India, He has a PhD in Pharmaceutical Sciences from CSIR CDRI and J.N.U New Delhi, India, an M.Pharm from IIT BHU,Varanasi, India and B.Pharm from Jamia Hamdard, New Delhi. He has more than ten years of research and academic experience with more than 30 publications and 10 book chapters to his credit. He has filed 7 Indian Patent and 1 Copyright. Recently he has edited a book on the Role of Novel Drug Delivery Vehicles in Nanobiomedicine. His current research interests include?targeted drug delivery systems, particle?engineering, controlled delivery?for neurodegenerative diseases,?dendrimer mediated drug delivery, solubilization and bioavailability enhancements. S.J.S. Flora Former Director, National Institute of Pharmaceutical Education and Research, Raebareli, Uttar Pradesh, India. Dr. S. J. S. Flora is the Former Director of the National Institute of Pharmaceutical Education and Research, Raebareli (NIPER-R), Uttar Pradesh, India, since 2016. Dr. Flora was head of Division of Pharmacology and Toxicology at Defense Research and Development Establishment, Gwalior, India. He earned his PhD in 1985 from CSIR-Indian Toxicology Research Center, Lucknow, and was a postdoctoral research associate at Utah State University, USA. His most highlighted contribution has been the development of a new drug for the therapy of chronic arsenic poisoning, which was approved by the Drug Controller General of India (DCGI). He has published more than 350 research papers, 75 review articles/chapters, 18 patents, and more than 16,000 citations. He has published 6 books including the prestigious Handbook of Arsenic Toxicology and the Handbook of Arsenic Toxicology and the Handbook on Biological Warfare Preparedness published by Elsevier/Academic Press (USA).
