Biomaterials for Angiogenesis and Vasculogenesis covers the application of materials designed to encourage new blood vessel formation. Angiogenesis and vasculogenesis play an important role in tissue engineering and regenerative medicine research by promoting vascular networks inside engineered tissues and thereby increasing tissue healing and regeneration. However, researchers are faced with the challenge of finding suitable materials for improving angiogenesis and vascular formation in assays. This book reviews a broad range of biomaterials for the promotion of blood vessel genesis, from polymers and bioactive glass, to nanomaterial scaffolds and 3D angiogenic constructs.
In addition, the book covers a variety of applications for biomaterials in tissue repair and regeneration, including cardiovascular regeneration, liver tissue engineering and much more. It will serve as a detailed reference for researchers in academia and industry, working in the fields of biomedical science and engineering, materials science, regenerative medicine and translational medicine.
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Table of Contents
1. Angiogenesis and Vasculogenesis: Status in Tissue Engineering2. Molecular mediators of vasculogenesis and angiogenesis
3. Role of cells in vasculogenesis and angiogenesis
4. The importance of extracellular matrix in vasculogenesis and angiogenesis
5. Role of growth factors in therapeutic angiogenesis
6. The interplay between the angiogenesis and neurogenesis during regeneration
7. Detection assays of vasculogenesis and angiogenesis
8. The effects of Medicinal Herbs and Phytochemicals on Angiogenesis and models of Wound Healing
9. Calcium Phosphates (CaPs) Bioceramics for Improved Angiogenesis
10. Angiogenesis induction by glass-ceramics and bioactive glass
11. Angiogenesis induction by natural and synthetic polymers
12. Composites for angiogenesis induction
13. Three dimensional (3D) angiogenic constructs
14. Engineering vascularized tissues/organs
15. Role of organic nano-materials in angiogenesis
16. Role of inorganic nano-materials in angiogenesis
17. Nano-sized carriers for delivery of angiogenic materials
18. Electrospun Nanofibers for Angiogenesis Strategies
19. Biomaterials for angiogenesis applications in an orthopedic context
20. Skin wounds healing
21. Bladder tissue engineering
Authors
Saeid Kargozar UT Southwestern Medical Center.Saeid Kargozar is a Fellow of the University of Texas Southwestern Medical Center (UTSW), USA. He was previously a Senior Assistant Professor of Tissue Engineering in the Department of Anatomy and Cell Biology, at Mashhad University of Medical Sciences in Iran. He received his M.S. in Medical Biotechnology in 2012 and his Ph.D. in Tissue Engineering in 2016, both from Tehran University of Medical Sciences, Iran. His current research interests include biocompatible materials and tissue engineering with special focus on bioactive glasses and the decellularized extracellular matrix (ECM). He is an active member of the American Ceramic Society and has published more than 118 peer-reviewed publications. According to a recent scientometric study published in PLOS Biology in 2021, he is listed amongst the top 2% of cited scientists in the world.
Masoud Mozafari Research Fellow, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Canada. Dr. Masoud Mozafari is a Fellow at Lunenfeld Tanenbaum Research Institute, Mount Sinai Health Hospital, University of Toronto. He was previously Assistant Professor and Director of the Bioengineering Lab, at the Nanotechnology and Advanced Materials Department, Materials and Energy Research Center, Cellular and Molecular Research Center, and Department of Tissue Engineering and Regenerative Medicine of the Iran University of Medical Sciences (IUMS), Tehran, Iran. Dr. Mozafari's research interests range across biomaterials, nanotechnology, and tissue engineering, and he is known for the development of strategies for the treatment of damaged tissues and organs, and controlling biological substances for targeted delivery into the human body. Dr. Mozafari has received several awards, including the Khwarizmi Award and the Julia Polak European Doctorate Award for outstanding translational research contributions to the field of biomaterials. He has also received the WIPO Medal for Inventors from The World Intellectual Property Organization (WIPO), in recognition of his contributions to economic and technological development. Dr. Mozafari is currently working on the editorial board of several journals.