The Neurobiology of the Gilles de la Tourette Syndrome and Chronic Tics, Part B, Volume Four reviews historical background, current nosology and guidelines. In addition, it includes an overview of pathophysiology, ranging from its genetic basis and changes in neurochemistry and electrophysiology to widespread neural circuits. Specific chapters cover The genetic basis of Gilles de la Tourette Syndrome, Genome-wide association study of Tourette Syndrome, De Novo mutations in Tourette Syndrome, Animal models for Tourette Syndrome, The neural-immune crosstalk in Tourette syndrome: from immunobiology to epistemology, Functional connectivity in the Gilles de la Tourette Syndrome, and much more.
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Table of Contents
Preface
Marc E. Lavoie and Andrea E. Cavanna
1. The genetic basis of Gilles de la Tourette syndrome
Sarah B. Abdallah, Evan Realbuto, Mary Oluwatosin Kaka, Kelly Yang, Apostolia Topaloudi, Peristera Paschou, Jeremiah M. Scharf and Thomas V. Fernandez
2. Studying the pathophysiology of tic disorders in animal models
Christopher Pittenger
3. The neural-immune crosstalk in Tourette syndrome: From immunobiology to epistemology
Yasamin Mahjoub, Davide Martino and Andrea E. Cavanna
4. Functional connectivity in the Gilles de la Tourette syndrome
Matthew Feigelis and Deanna J. Greene
5. Perception-action integration in Gilles de la Tourette syndrome
Theresa Paulus, Christian Beste and Alexander M�nchau
6. The pharmacological treatment of Tourette syndrome
Jos� Fidel Baizabal-Carvallo and Joseph Jankovic
7. Ecopipam: A D1 receptor antagonist for the treatment of Tourette syndrome
Richard E. Chipkin, Donald L. Gilbert and Atul Mahableshwarkar
8. Atypical antipsychotics for treatment of Tourette syndrome
Vamsi K. Kalari, Peter E. Morrison and Cathy L. Budman
9. Alpha agonists for the treatment of Tourette syndrome
Nick Cothros and Tamara Pringsheim
10. Cannabinoids: Possible role in the pathophysiology and therapy of Gilles de la Tourette syndrome
Natalia Szejko and Kirsten M�ller-Vahl
11. Novel potential avenues for the therapy of Tourette syndrome: Cannabinoid and steroid-based tools
Marco Bortolato and Roberto Cadeddu
12. Non-invasive brain stimulation for the treatment of Tourette's syndrome
Sneha Chenji, Kayla D. Stone and Frank P. MacMaster
13. Entrainment of movement-related brain oscillations to improve symptoms in Tourette syndrome
Mairi Houlgreave, B�rbara Morera Maiquez, Katherine Dyke, Georgina Jackson and Stephen Jackson
14. Network oscillatory activity in chronic tics and Tourette syndrome
Joohi Jimenez-Shahed
