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Bacterial Survival in the Hostile Environment. Developments in Applied Microbiology and Biotechnology

  • Book

  • September 2022
  • Elsevier Science and Technology
  • ID: 5562022

Variety of bacteria are present in our environment but only a few of these bacteria causes diseases in their hosts including humans. These bacteria face different stresses in the environment as well as inside the host and adapt number of strategies for their survival. In 5 parts Bacterial Survival in the Hostile Environment covers all tactics and strategies adopted by bacteria for their survival under stressed conditions and will be focused on mechanistic insights of pathogenic adaptations to host environments (acidic environment, microaerobic conditions, immune system stress, metal stress etc., modulation of host pathways by pathogens for survival, dormancy, drug tolerance and resistance, proteins for stress survival). The content also includes different adaptation mechanisms of extremophiles to extreme environment, provides a complete and globally available advance knowledge related to bacterial survival from different perspectives and reviews the knowledge gaps and future prospects in the field of microbial adaptation for sustainable development of in the field of infection biology and pharmaceutics.

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Table of Contents

Chapter 1. Mycobacterium tuberculosis adaptation to host environment
Chapter 2. Modulation of host pathways by Mycobacterium tuberculosis for survival
Chapter 3. Signaling nucleotides in bacteria
Chapter 4. The fish immune armaments in response to pathogen invasion-a tour inside the macrophages
Chapter 5. Essential proteins for the survival of bacteria in hostile environment
Chapter 6. Kinases and phosphatases in bacterial survival in hostile environment
Chapter 7. Antimicrobial resistance-a serious global threat
Chapter 8. Combination of virulence and antibiotic resistance: a successful bacterial strategy to survive under hostile environments
Chapter 9. Mechanisms of biofilm-based antibiotic resistance and tolerance in Mycobacterium tuberculosis
Chapter 10. Biofilms: cities of microorganisms
Chapter 11. Biofilm: a coordinated response of bacteria against stresses
Chapter 12. The bacterial communication system and its interference as an antivirulence strategy
Chapter 13. Microbial adaptations in extreme environmental conditions
Chapter 14. Adaptation strategies of piezophilic microbes
Chapter 15. Survival and adaptation strategies of microorganisms in the extreme radiation
Chapter 16. Adaptation strategies of thermophilic microbes

Authors

Ashutosh Kumar Tripura University (A Central University), Department of Microbiology, Suryamaninagar, Agartala, Tripura , India. Dr. Ashutosh Kumar is an active researcher and scientific writer in his field for over 14 years and presently working at Department of Microbiology, Tripura University (A Central University), Suryamaninagar, Agartala, Tripura, India. He received MSc and PhD degree in Biotechnology from University of Hyderabad, India. He did his postdoctoral research at TIFR-National Centre for Biological Sciences Bangalore, Indian Institute of Technology Delhi and Jamia Hamdard, New Delhi, India. He also worked as a Visiting Research Scientist at Robert Koch Institute Berlin, Germany. He has made significant contributions to the study of virulence mechanisms and strategies of survival, adaptation, and persistence of Mycobacterium tuberculosis. He was involved in identification of an enzyme from M. tuberculosis that promote biofilm formation and drugs that enhanced the potency of two current anti-tuberculosis antibiotics. He received many scholarships, awards, and fellowship during his education. He has many publications in international journals and books. Shivendra Tenguria Project Scientist, Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center (UCLA), Los Angeles, CA, United States. Dr. Tenguria is an active researcher and currently working as Project Scientist in Cedars-Sinai Medical Center, Los Angeles, CA USA. He has been actively involved in research and training of graduate and undergraduate students. He received his MSc in Life Sciences from University of Rajasthan, Jaipur and PhD in Biotechnology from University of Hyderabad, Hyderabad, India. He received his postdoctoral training from Purdue University, Indiana, USA and Cedars-Sinai Medical Center (UCLA), Los Angeles, California, USA. Currently, he is working in the area of molecular innate immunity to unravel molecular signaling mechanics for sensing danger (infectious pathogens) signals through cytosolic receptors of the innate immune system of human and mouse hosts. With his doctoral and postdoctoral fellowships and research in the area of host-microbe interactions, bacterial survival and pathogenesis, he made seminal contributions by publishing in international Jr (Cell Host-Microbe, Nature Commun, Frontiers).