Viruses: From Understanding to Investigation, Second Edition presents the definitions and unique characteristics of viruses. The book includes major topics such as virus lifecycle, structure, taxonomy, evolution, history, host-virus interactions, and methods to study. In addition, the book assesses the connections between the aforementioned topics and provides an integrated approach and in-depth understanding of how viruses work. The new edition also provides an expanded methods chapter containing new information on deep sequencing for in virus identification, mathematical formulas to calculate titers and a description of quantitiative PCR for enumerating viruses. The vaccine chapter has been updated to include vaccine efficacy, mRNA vaccines and SARS-CoV-2 vaccine development. The viral pathogenesis chapter has been expanded to include mechanisms of virally induced cancers. Viral taxonomy sections have been updated and chapters revised to accommodate new virus family designations. New chapters include nucleocytoplasmic viruses (very large DNA viruses), replication of viroids and COVID-19/SARS-CoV-2.
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Table of Contents
1. Introduction to animal viruses 2. Virus structure 3. Virus interactions with the cell 4. Methods to study viruses 5. Virus transmission and epidemiology 6. Immunity and resistance to viruses 7. Viral vaccines 8. Antiviral agents 9. Virus evolution and genetics 10. Viral pathogenesis 11. Introduction to RNA viruses 12. Family Picornaviridae 13. Family Caliciviridae 14. Family Hepeviridae 15. Family Astroviridae 16. Family Flaviviridae Families Togaviridae and Matonaviridae 18. Family Coronaviridae 19. SARS-CoV-2/COVID-19 20. Family Arteriviridae 21. Family Rhabdoviridae 22. Family Paramyxoviridae 23. Family Pneumoviridae 24. Family Filoviridae 25. Family Bornaviridae 26. Family Orthomyxoviridae 27. Family Hantaviridae 28. Order Bunyavirales: Families Peribunyaviridae, Phenuiviridae, and Nairoviridae 29. Family Arenaviridae 30. Family Reoviridae 31. Family Birnaviridae 32. Hepatitis delta virus 33. Introduction to DNA viruses 34. Family Parvoviridae 35. Other small DNA viruses 36. Family Polyomaviridae 37. Family Papillomaviridae 38. Family Adenoviridae 39. Family Herpesviridae 40. Family Poxviridae 41. Other large DNA viruses 42. Family Retroviridae 43. Replication and pathogenesis of human immunodeficiency virus 44. Family Hepadnaviridae
