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Non-alcoholic Steatohepatitis Drug Global Market Insights 2025, Analysis and Forecast to 2030, by Market Participants, Regions, Technology- Product Image
Non-alcoholic Steatohepatitis Drug Global Market Insights 2025, Analysis and Forecast to 2030, by Market Participants, Regions, Technology- Product Image
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Non-alcoholic Steatohepatitis Drug Global Market Insights 2025, Analysis and Forecast to 2030, by Market Participants, Regions, Technology

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  • 104 Pages
  • March 2025
  • Region: Global
  • Prof Research
  • ID: 5598855
Description Jump to:
Non-alcoholic Steatohepatitis (NASH) is a severe form of non-alcoholic fatty liver disease marked by liver inflammation and fibrosis, often linked to obesity and metabolic syndrome. Globally, NASH prevalence rose from 264 million in 2018 to 296 million in 2023, projected to reach 342 million by 2030. The NASH Drug market focuses on therapies to halt progression, reduce fat accumulation, and prevent cirrhosis, with resmetirom - approved by the FDA in March 2024 by Madrigal Pharmaceuticals - as the first drug for moderate-to-advanced NASH fibrosis. The industry is characterized by intense R&D, addressing a growing epidemic with significant unmet needs and a shift toward metabolic-targeted therapies.

Market Size and Growth Forecast

The global Non-alcoholic Steatohepatitis Drug market is estimated at USD 0.3 billion to USD 0.6 billion in 2025, with an extraordinary CAGR of 100% to 110% through 2030, potentially reaching USD 10 billion to USD 24 billion. This explosive growth reflects resmetirom’s approval and robust pipeline activity.

Regional Analysis

  • North America: Expected at 95% to 105%, the U.S. leads with high obesity rates and advanced healthcare. Trends focus on metabolic drugs and diagnostics.
  • Europe: Forecasted at 90% to 100%, Germany and France grow rapidly. Trends emphasize lifestyle-linked therapies.
  • Asia Pacific: Projected at 100% to 110%, China drives growth with rising prevalence. Trends highlight local R&D.
  • South Ameica: Anticipated at 85% to 95%, Brazil emerges. Trends favor affordable options.
  • Middle East and Africa: Expected at 80% to 90%, UAE leads. Trends focus on awareness and access.

Key Market Players

  • AstraZeneca PLC: A UK leader, AstraZeneca targets metabolic diseases like NASH.
  • Eli Lilly: A U.S. firm, Lilly advances NASH therapies with metabolic focus.
  • Gilead Sciences: A U.S. giant, Gilead explores liver disease solutions.
  • Merck & Co. Inc.: A U.S. player, Merck innovates in NASH treatments.
  • Novo Nordisk: A Danish company, Novo Nordisk leverages diabetes expertise for NASH.
  • Novartis AG: A Swiss firm, Novartis focuses on fibrosis therapies.
  • Pfizer Inc.: A U.S. leader, Pfizer targets metabolic liver conditions.
  • Roche Holding AG: A Swiss giant, Roche explores NASH innovations.
  • Enanta Pharmaceuticals Inc.: A U.S. biotech, Enanta develops liver-targeted drugs.
  • Ionis Pharmaceuticals Inc.: A U.S. entity, Ionis advances RNA therapies for NASH.
  • NGM Biopharmaceuticals Inc.: A U.S. firm, NGM targets metabolic pathways.
  • Pliant Therapeutics Inc.: A U.S. biotech, Pliant focuses on anti-fibrotic agents.
  • Terns Pharmaceuticals Inc.: A U.S. company, Terns innovates in NASH treatments.
  • 89bio Inc.: A U.S. entity, 89bio develops metabolic therapies.

Porter’s Five Forces Analysis

  • Threat of New Entrants: High, with blockbuster potential attracting biotechs despite R&D costs.
  • Threat of Substitutes: Moderate, with lifestyle interventions competing, but drugs offer scalability.
  • Bargaining Power of Buyers: Moderate, as unmet needs limit options, though insurers push pricing.
  • Bargaining Power of Suppliers: Low-to-moderate, with broad supply chains supporting drug production.
  • Competitive Rivalry: Intense, driven by first-mover advantages and pipeline races among Gilead and Merck.

Market Opportunities and Challenges

Opportunities

  • Rising Prevalence: 342 million cases by 2030 create vast demand for NASH drugs.
  • First Approval: Resmetirom’s success sets a precedent, accelerating market entry.
  • Metabolic Focus: Overlap with obesity and diabetes opens cross-therapeutic potential.
  • Investment Surge: High growth rates attract significant R&D funding.

Challenges

  • Diagnostic Barriers: NASH’s silent progression delays treatment, limiting market reach.
  • High Costs: Expensive drugs like resmetirom challenge affordability in emerging markets.
  • Regulatory Hurdles: Rigorous efficacy proof slows pipeline approvals.
  • Competition: Crowded pipeline increases rivalry, risking market saturation.

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Table of Contents

Chapter 1 Executive SummaryChapter 2 Abbreviation and Acronyms
Chapter 3 Preface
3.1 Research Scope
3.2 Research Sources
3.2.1 Data Sources
3.2.2 Assumptions
3.3 Research Method
Chapter 4 Market Landscape
4.1 Market Overview
4.2 Classification/Types
4.3 Application/End Users
Chapter 5 Market Trend Analysis
5.1 Introduction
5.2 Drivers
5.3 Restraints
5.4 Opportunities
5.5 Threats
Chapter 6 Industry Chain Analysis
6.1 Upstream/Suppliers Analysis
6.2 Non-Alcoholic Steatohepatitis Drug Analysis
6.2.1 Technology Analysis
6.2.2 Cost Analysis
6.2.3 Market Channel Analysis
6.3 Downstream Buyers/End Users
Chapter 7 Latest Market Dynamics
7.1 Latest News
7.2 Merger and Acquisition
7.3 Planned/Future Project
7.4 Policy Dynamics
Chapter 8 Historical and Forecast Non-Alcoholic Steatohepatitis Drug Market in North America (2020-2030)
8.1 Non-Alcoholic Steatohepatitis Drug Market Size
8.2 Non-Alcoholic Steatohepatitis Drug Market by End Use
8.3 Competition by Players/Suppliers
8.4 Non-Alcoholic Steatohepatitis Drug Market Size by Type
8.5 Key Countries Analysis
8.5.1 United States
8.5.2 Canada
8.5.3 Mexico
Chapter 9 Historical and Forecast Non-Alcoholic Steatohepatitis Drug Market in South America (2020-2030)
9.1 Non-Alcoholic Steatohepatitis Drug Market Size
9.2 Non-Alcoholic Steatohepatitis Drug Market by End Use
9.3 Competition by Players/Suppliers
9.4 Non-Alcoholic Steatohepatitis Drug Market Size by Type
9.5 Key Countries Analysis
9.5.1 Brazil
9.5.2 Argentina
9.5.3 Chile
9.5.4 Peru
Chapter 10 Historical and Forecast Non-Alcoholic Steatohepatitis Drug Market in Asia & Pacific (2020-2030)
10.1 Non-Alcoholic Steatohepatitis Drug Market Size
10.2 Non-Alcoholic Steatohepatitis Drug Market by End Use
10.3 Competition by Players/Suppliers
10.4 Non-Alcoholic Steatohepatitis Drug Market Size by Type
10.5 Key Countries Analysis
10.5.1 China
10.5.2 India
10.5.3 Japan
10.5.4 South Korea
10.5.5 Southeast Asia
10.5.6 Australia
Chapter 11 Historical and Forecast Non-Alcoholic Steatohepatitis Drug Market in Europe (2020-2030)
11.1 Non-Alcoholic Steatohepatitis Drug Market Size
11.2 Non-Alcoholic Steatohepatitis Drug Market by End Use
11.3 Competition by Players/Suppliers
11.4 Non-Alcoholic Steatohepatitis Drug Market Size by Type
11.5 Key Countries Analysis
11.5.1 Germany
11.5.2 France
11.5.3 United Kingdom
11.5.4 Italy
11.5.5 Spain
11.5.6 Belgium
11.5.7 Netherlands
11.5.8 Austria
11.5.9 Poland
11.5.10 Russia
Chapter 12 Historical and Forecast Non-Alcoholic Steatohepatitis Drug Market in MEA (2020-2030)
12.1 Non-Alcoholic Steatohepatitis Drug Market Size
12.2 Non-Alcoholic Steatohepatitis Drug Market by End Use
12.3 Competition by Players/Suppliers
12.4 Non-Alcoholic Steatohepatitis Drug Market Size by Type
12.5 Key Countries Analysis
12.5.1 Egypt
12.5.2 Israel
12.5.3 South Africa
12.5.4 Gulf Cooperation Council Countries
12.5.5 Turkey
Chapter 13 Summary For Global Non-Alcoholic Steatohepatitis Drug Market (2020-2025)
13.1 Non-Alcoholic Steatohepatitis Drug Market Size
13.2 Non-Alcoholic Steatohepatitis Drug Market by End Use
13.3 Competition by Players/Suppliers
13.4 Non-Alcoholic Steatohepatitis Drug Market Size by Type
Chapter 14 Global Non-Alcoholic Steatohepatitis Drug Market Forecast (2025-2030)
14.1 Non-Alcoholic Steatohepatitis Drug Market Size Forecast
14.2 Non-Alcoholic Steatohepatitis Drug Application Forecast
14.3 Competition by Players/Suppliers
14.4 Non-Alcoholic Steatohepatitis Drug Type Forecast
Chapter 15 Analysis of Global Key Vendors
15.1 AstraZeneca PLC
15.1.1 Company Profile
15.1.2 Main Business and Non-alcoholic Steatohepatitis Drug Information
15.1.3 SWOT Analysis of AstraZeneca PLC
15.1.4 AstraZeneca PLC Non-alcoholic Steatohepatitis Drug Revenue, Gross Margin and Market Share (2020-2025)
15.2 Eli Lilly
15.2.1 Company Profile
15.2.2 Main Business and Non-alcoholic Steatohepatitis Drug Information
15.2.3 SWOT Analysis of Eli Lilly
15.2.4 Eli Lilly Non-alcoholic Steatohepatitis Drug Revenue, Gross Margin and Market Share (2020-2025)
15.3 Gilead Sciences
15.3.1 Company Profile
15.3.2 Main Business and Non-alcoholic Steatohepatitis Drug Information
15.3.3 SWOT Analysis of Gilead Sciences
15.3.4 Gilead Sciences Non-alcoholic Steatohepatitis Drug Revenue, Gross Margin and Market Share (2020-2025)
15.4 Merck & Co. Inc.
15.4.1 Company Profile
15.4.2 Main Business and Non-alcoholic Steatohepatitis Drug Information
15.4.3 SWOT Analysis of Merck & Co. Inc.
15.4.4 Merck & Co. Inc. Non-alcoholic Steatohepatitis Drug Revenue, Gross Margin and Market Share (2020-2025)
15.5 Novo Nordisk
15.5.1 Company Profile
15.5.2 Main Business and Non-alcoholic Steatohepatitis Drug Information
15.5.3 SWOT Analysis of Novo Nordisk
15.5.4 Novo Nordisk Non-alcoholic Steatohepatitis Drug Revenue, Gross Margin and Market Share (2020-2025)
15.6 Novartis AG
15.6.1 Company Profile
15.6.2 Main Business and Non-alcoholic Steatohepatitis Drug Information
15.6.3 SWOT Analysis of Novartis AG
15.6.4 Novartis AG Non-alcoholic Steatohepatitis Drug Revenue, Gross Margin and Market Share (2020-2025)
15.7 Pfizer Inc.
15.7.1 Company Profile
15.7.2 Main Business and Non-alcoholic Steatohepatitis Drug Information
15.7.3 SWOT Analysis of Pfizer Inc.
15.7.4 Pfizer Inc. Non-alcoholic Steatohepatitis Drug Revenue, Gross Margin and Market Share (2020-2025)
15.8 Roche Holding AG
15.8.1 Company Profile
15.8.2 Main Business and Non-alcoholic Steatohepatitis Drug Information
15.8.3 SWOT Analysis of Roche Holding AG
15.8.4 Roche Holding AG Non-alcoholic Steatohepatitis Drug Revenue, Gross Margin and Market Share (2020-2025)
15.9 Enanta Pharmaceuticals Inc.
15.9.1 Company Profile
15.9.2 Main Business and Non-alcoholic Steatohepatitis Drug Information
15.9.3 SWOT Analysis of Enanta Pharmaceuticals Inc.
15.9.4 Enanta Pharmaceuticals Inc. Non-alcoholic Steatohepatitis Drug Revenue, Gross Margin and Market Share (2020-2025)
15.10 Ionis Pharmceuticals Inc.
15.10.1 Company Profile
15.10.2 Main Business and Non-alcoholic Steatohepatitis Drug Information
15.10.3 SWOT Analysis of Ionis Pharmceuticals Inc.
15.10.4 Ionis Pharmceuticals Inc. Non-alcoholic Steatohepatitis Drug Revenue, Gross Margin and Market Share (2020-2025)
15.11 NGM Biopharmaceuticals Inc.
15.11.1 Company Profile
15.11.2 Main Business and Non-alcoholic Steatohepatitis Drug Information
15.11.3 SWOT Analysis of NGM Biopharmaceuticals Inc.
15.11.4 NGM Biopharmaceuticals Inc. Non-alcoholic Steatohepatitis Drug Revenue, Gross Margin and Market Share (2020-2025)
15.12 Pliant Therapeutics inc.
15.12.1 Company Profile
15.12.2 Main Business and Non-alcoholic Steatohepatitis Drug Information
15.12.3 SWOT Analysis of Pliant Therapeutics inc.
15.12.4 Pliant Therapeutics inc. Non-alcoholic Steatohepatitis Drug Revenue, Gross Margin and Market Share (2020-2025)
15.13 Terns Pharmaceuticals Inc.
15.13.1 Company Profile
15.13.2 Main Business and Non-alcoholic Steatohepatitis Drug Information
15.13.3 SWOT Analysis of Terns Pharmaceuticals Inc.
15.13.4 Terns Pharmaceuticals Inc. Non-alcoholic Steatohepatitis Drug Revenue, Gross Margin and Market Share (2020-2025)
15.14 89bio Inc.
15.14.1 Company Profile
15.14.2 Main Business and Non-alcoholic Steatohepatitis Drug Information
15.14.3 SWOT Analysis of 89bio Inc.
15.14.4 89bio Inc. Non-alcoholic Steatohepatitis Drug Revenue, Gross Margin and Market Share (2020-2025)
List of Tables and Figures
Table Abbreviation and Acronyms
Table Research Scope of Non-Alcoholic Steatohepatitis Drug Report
Table Data Sources of Non-Alcoholic Steatohepatitis Drug Report
Table Major Assumptions of Non-Alcoholic Steatohepatitis Drug Report
Figure Market Size Estimated Method
Figure Major Forecasting Factors
Figure Non-Alcoholic Steatohepatitis Drug Picture
Table Non-Alcoholic Steatohepatitis Drug Classification
Table Non-Alcoholic Steatohepatitis Drug Applications
Table Drivers of Non-Alcoholic Steatohepatitis Drug Market
Table Restraints of Non-Alcoholic Steatohepatitis Drug Market
Table Opportunities of Non-Alcoholic Steatohepatitis Drug Market
Table Threats of Non-Alcoholic Steatohepatitis Drug Market
Table COVID-19 Impact For Non-Alcoholic Steatohepatitis Drug Market
Table Raw Materials Suppliers
Table Different Production Methods of Non-Alcoholic Steatohepatitis Drug
Table Cost Structure Analysis of Non-Alcoholic Steatohepatitis Drug
Table Key End Users
Table Latest News of Non-Alcoholic Steatohepatitis Drug Market
Table Merger and Acquisition
Table Planned/Future Project of Non-Alcoholic Steatohepatitis Drug Market
Table Policy of Non-Alcoholic Steatohepatitis Drug Market
Table 2020-2030 North America Non-Alcoholic Steatohepatitis Drug Market Size
Figure 2020-2030 North America Non-Alcoholic Steatohepatitis Drug Market Size and CAGR
Table 2020-2030 North America Non-Alcoholic Steatohepatitis Drug Market Size by Application
Table 2020-2025 North America Non-Alcoholic Steatohepatitis Drug Key Players Revenue
Table 2020-2025 North America Non-Alcoholic Steatohepatitis Drug Key Players Market Share
Table 2020-2030 North America Non-Alcoholic Steatohepatitis Drug Market Size by Type
Table 2020-2030 United States Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Canada Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Mexico Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 South America Non-Alcoholic Steatohepatitis Drug Market Size
Figure 2020-2030 South America Non-Alcoholic Steatohepatitis Drug Market Size and CAGR
Table 2020-2030 South America Non-Alcoholic Steatohepatitis Drug Market Size by Application
Table 2020-2025 South America Non-Alcoholic Steatohepatitis Drug Key Players Revenue
Table 2020-2025 South America Non-Alcoholic Steatohepatitis Drug Key Players Market Share
Table 2020-2030 South America Non-Alcoholic Steatohepatitis Drug Market Size by Type
Table 2020-2030 Brazil Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Argentina Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Chile Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Peru Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Asia & Pacific Non-Alcoholic Steatohepatitis Drug Market Size
Figure 2020-2030 Asia & Pacific Non-Alcoholic Steatohepatitis Drug Market Size and CAGR
Table 2020-2030 Asia & Pacific Non-Alcoholic Steatohepatitis Drug Market Size by Application
Table 2020-2025 Asia & Pacific Non-Alcoholic Steatohepatitis Drug Key Players Revenue
Table 2020-2025 Asia & Pacific Non-Alcoholic Steatohepatitis Drug Key Players Market Share
Table 2020-2030 Asia & Pacific Non-Alcoholic Steatohepatitis Drug Market Size by Type
Table 2020-2030 China Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 India Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Japan Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 South Korea Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Southeast Asia Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Australia Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Europe Non-Alcoholic Steatohepatitis Drug Market Size
Figure 2020-2030 Europe Non-Alcoholic Steatohepatitis Drug Market Size and CAGR
Table 2020-2030 Europe Non-Alcoholic Steatohepatitis Drug Market Size by Application
Table 2020-2025 Europe Non-Alcoholic Steatohepatitis Drug Key Players Revenue
Table 2020-2025 Europe Non-Alcoholic Steatohepatitis Drug Key Players Market Share
Table 2020-2030 Europe Non-Alcoholic Steatohepatitis Drug Market Size by Type
Table 2020-2030 Germany Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 France Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 United Kingdom Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Italy Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Spain Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Belgium Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Netherlands Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Austria Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Poland Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Russia Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 MEA Non-Alcoholic Steatohepatitis Drug Market Size
Figure 2020-2030 MEA Non-Alcoholic Steatohepatitis Drug Market Size and CAGR
Table 2020-2030 MEA Non-Alcoholic Steatohepatitis Drug Market Size by Application
Table 2020-2025 MEA Non-Alcoholic Steatohepatitis Drug Key Players Revenue
Table 2020-2025 MEA Non-Alcoholic Steatohepatitis Drug Key Players Market Share
Table 2020-2030 MEA Non-Alcoholic Steatohepatitis Drug Market Size by Type
Table 2020-2030 Egypt Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Israel Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 South Africa Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Gulf Cooperation Council Countries Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2030 Turkey Non-Alcoholic Steatohepatitis Drug Market Size
Table 2020-2025 Global Non-Alcoholic Steatohepatitis Drug Market Size by Region
Table 2020-2025 Global Non-Alcoholic Steatohepatitis Drug Market Size Share by Region
Table 2020-2025 Global Non-Alcoholic Steatohepatitis Drug Market Size by Application
Table 2020-2025 Global Non-Alcoholic Steatohepatitis Drug Market Share by Application
Table 2020-2025 Global Non-Alcoholic Steatohepatitis Drug Key Vendors Revenue
Figure 2020-2025 Global Non-Alcoholic Steatohepatitis Drug Market Size and Growth Rate
Table 2020-2025 Global Non-Alcoholic Steatohepatitis Drug Key Vendors Market Share
Table 2020-2025 Global Non-Alcoholic Steatohepatitis Drug Market Size by Type
Table 2020-2025 Global Non-Alcoholic Steatohepatitis Drug Market Share by Type
Table 2025-2030 Global Non-Alcoholic Steatohepatitis Drug Market Size by Region
Table 2025-2030 Global Non-Alcoholic Steatohepatitis Drug Market Size Share by Region
Table 2025-2030 Global Non-Alcoholic Steatohepatitis Drug Market Size by Application
Table 2025-2030 Global Non-Alcoholic Steatohepatitis Drug Market Share by Application
Table 2025-2030 Global Non-Alcoholic Steatohepatitis Drug Key Vendors Revenue
Figure 2025-2030 Global Non-Alcoholic Steatohepatitis Drug Market Size and Growth Rate
Table 2025-2030 Global Non-Alcoholic Steatohepatitis Drug Key Vendors Market Share
Table 2025-2030 Global Non-Alcoholic Steatohepatitis Drug Market Size by Type
Table 2025-2030 Non-Alcoholic Steatohepatitis Drug Global Market Share by Type

Companies Mentioned

  • AstraZeneca PLC
  • Eli Lilly
  • Gilead Sciences
  • Merck & Co. Inc.
  • Novo Nordisk
  • Novartis AG
  • Pfizer Inc.
  • Roche Holding AG
  • Enanta Pharmaceuticals Inc.
  • Ionis Pharmceuticals Inc.
  • NGM Biopharmaceuticals Inc.
  • Pliant Therapeutics inc.
  • Terns Pharmaceuticals Inc.
  • 89bio Inc.

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