“BOMEDEMSTAT Emerging Drug Insight and Market Forecast - 2032” report provides comprehensive insights about BOMEDEMSTAT for Polycythemia Vera in the 7MM. A detailed picture of the BOMEDEMSTAT for Polycythemia Vera in the 7MM, i.e., United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan, for the study period 2019-2032 is provided in this report along with a detailed description of the BOMEDEMSTAT for Polycythemia Vera. The report provides insight about mechanism of action, dosage and administration, as well as research and development activity including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the BOMEDEMSTAT market forecast, analysis for Polycythemia Vera in the 7MM, descriptive analysis such as SWOT, analyst views, comprehensive overview of market competitors, and brief about emerging therapies in Polycythemia Vera.
IMG-7289 demonstrated robust in vivo anti-tumor efficacy in nonclinical studies across a range of myeloid malignancies models, including the myeloproliferative neoplasms that encompass myelofibrosis, essential thrombocythemia, and Polycythemia Vera as a single agent and in combination with other chemotherapeutic agents. IMG-7289 also shows activity against solid tumors in combination with checkpoint inhibitor agents in nonclinical models BOMEDEMSTAT was investigated in multiple mouse models of myeloproliferative neoplasms using the same mutant alleles found in patients with myeloproliferative neoplasms (MPNs). Inhibiting LSD1 in animal models of MPN has demonstrated additional biological effects that Imago hopes translate to clinical benefits for patients.
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Drug Summary
BOMEDEMSTAT is an orally bioavailable small molecule developed by Imago BioSciences that inhibits lysine-specific demethylase 1 (LSD1 or KDM1A) - an enzyme shown to be vital in cancer stem/progenitor cells, particularly neoplastic bone marrow cells. LSD1 inhibition modulates the proliferation of malignant blood cells and therefore represents a viable therapeutic approach to treating PV, an MPN characterized by the excessive production of red blood cells. Currently, there are no disease-modifying therapies for the PV. BOMEDEMSTAT represents a novel therapeutic option for this patient population.IMG-7289 demonstrated robust in vivo anti-tumor efficacy in nonclinical studies across a range of myeloid malignancies models, including the myeloproliferative neoplasms that encompass myelofibrosis, essential thrombocythemia, and Polycythemia Vera as a single agent and in combination with other chemotherapeutic agents. IMG-7289 also shows activity against solid tumors in combination with checkpoint inhibitor agents in nonclinical models BOMEDEMSTAT was investigated in multiple mouse models of myeloproliferative neoplasms using the same mutant alleles found in patients with myeloproliferative neoplasms (MPNs). Inhibiting LSD1 in animal models of MPN has demonstrated additional biological effects that Imago hopes translate to clinical benefits for patients.
Scope of the Report
The report provides insights into:
- A comprehensive product overview including the BOMEDEMSTAT description, mechanism of action, dosage and administration, research and development activities in Polycythemia Vera.
- Elaborated details on BOMEDEMSTAT regulatory milestones and other development activities have been provided in this report.
- The report also highlights the BOMEDEMSTAT research and development activity in Polycythemia Vera details across the United States, Europe and Japan.
- The report also covers the patents information with expiry timeline around BOMEDEMSTAT.
- The report contains forecasted sales of BOMEDEMSTAT for Polycythemia Vera till 2032.
- Comprehensive coverage of the late-stage emerging therapies for Polycythemia Vera.
- The report also features the SWOT analysis with analyst views for BOMEDEMSTAT in Polycythemia Vera.
Methodology
The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by the publisher's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.BOMEDEMSTAT Analytical Perspective
In-depth BOMEDEMSTAT Market Assessment
This report provides a detailed market assessment of BOMEDEMSTAT in Polycythemia Vera in the 7MM, i.e., United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan. This segment of the report provides forecasted sales data from 2026 to 2032.BOMEDEMSTAT Clinical Assessment
The report provides the clinical trials information of BOMEDEMSTAT for Polycythemia Vera covering trial interventions, trial conditions, trial status, start and completion dates.Report Highlights
- In the coming years, the market scenario for Polycythemia Vera is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
- The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence BOMEDEMSTAT dominance.
- Other emerging products for Polycythemia Vera are expected to give tough market competition to BOMEDEMSTAT and launch of late-stage emerging therapies in the near future will significantly impact the market.
- A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of BOMEDEMSTAT in Polycythemia Vera.
- The in-depth analysis of the forecasted sales data of BOMEDEMSTAT from 2026 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the BOMEDEMSTAT in Polycythemia Vera.
Key Questions Answered
- What is the product type, route of administration and mechanism of action of BOMEDEMSTAT?
- What is the clinical trial status of the study related to BOMEDEMSTAT in Polycythemia Vera and study completion date?
- What are the key collaborations, mergers and acquisitions, licensing and other activities related to the BOMEDEMSTAT development?
- What are the key designations that have been granted to BOMEDEMSTAT for Polycythemia Vera?
- What is the forecasted market scenario of BOMEDEMSTAT for Polycythemia Vera?
- What are the forecasted sales of BOMEDEMSTAT in the 7MM, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan?
- What are the other emerging products available in Polycythemia Vera and how are they giving competition to BOMEDEMSTAT for Polycythemia Vera?
- Which are the late-stage emerging therapies under development for the treatment of Polycythemia Vera?
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Table of Contents
1. Report Introduction2. BOMEDEMSTAT Overview in Polycythemia Vera
2.1. Product Detail
2.2. Clinical Development
2.2.1. Clinical Studies
2.2.2. Clinical Trials Information
2.2.3. Safety and Efficacy
2.3. Other Development Activities
2.4. Product Profile
3. Competitive Landscape (Marketed Therapies)
4. Competitive Landscape (Late-stage Emerging Therapies)*
5. BOMEDEMSTAT Market Assessment
5.1. Market Outlook of BOMEDEMSTAT in Polycythemia Vera
5.2. 7MM Market Analysis
5.2.1. Market Size of BOMEDEMSTAT in the 7MM for Polycythemia Vera
5.3. Country-wise Market Analysis
5.3.1. Market Size of BOMEDEMSTAT in the United States for Polycythemia Vera
5.3.2. Market Size of BOMEDEMSTAT in Germany for Polycythemia Vera
5.3.3. Market Size of BOMEDEMSTAT in France for Polycythemia Vera
5.3.4. Market Size of BOMEDEMSTAT in Italy for Polycythemia Vera
5.3.5. Market Size of BOMEDEMSTAT in Spain for Polycythemia Vera
5.3.6. Market Size of BOMEDEMSTAT in the United Kingdom for Polycythemia Vera
5.3.7. Market Size of BOMEDEMSTAT in Japan for Polycythemia Vera
6. SWOT Analysis
7. Analysts’ Views
8. Appendix
8.1. Bibliography
8.2. Report Methodology
9. Publisher Capabilities
10. Disclaimer
11. About the Publisher
12. Report Purchase OptionList of Tables
Table 1: BOMEDEMSTAT, Clinical Trial Description, 2022
Table 2: BOMEDEMSTAT(IMG-7289): General Description
Table 3: Competitive Landscape (Marketed Therapies)
Table 4: Competitive Landscape (Emerging Therapies)
Table 5: BOMEDEMSTAT (IMG-7289) Market Size in the 7MM, in USD million (2019-2032)
Table 6: BOMEDEMSTAT (IMG-7289) Market Size in the United States, in USD million (2019-2032)
Table 7: BOMEDEMSTAT (IMG-7289) Market Size in Germany, in USD million (2019-2032)
Table 8: BOMEDEMSTAT (IMG-7289) Market Size in France, in USD million (2019-2032)
Table 9: BOMEDEMSTAT (IMG-7289) Market Size in Italy, in USD million (2019-2032)
Table 10: BOMEDEMSTAT (IMG-7289) Market Size in Spain, in USD million (2019-2032)
Table 11: BOMEDEMSTAT (IMG-7289) Market Size in the United Kingdom, in USD million (2019-2032)
Table 12: BOMEDEMSTAT (IMG-7289) Market Size in Japan, in USD million (2019-2032)List of Figures
Figure 1: Market Size of BOMEDEMSTAT (IMG-7289) in the 7MM, in USD million (2019-2032)
Figure 2: Market Size of BOMEDEMSTAT (IMG-7289) in the United States, in USD million (2019-2032)
Figure 3: Market Size of BOMEDEMSTAT (IMG-7289) in Germany, in USD million (2019-2032)
Figure 4: Market Size of BOMEDEMSTAT (IMG-7289) in France, in USD million (2019-2032)
Figure 5: Market Size of BOMEDEMSTAT (IMG-7289) in Italy, in USD million (2019-2032)
Figure 6: Market Size of BOMEDEMSTAT (IMG-7289) in Spain, in USD million (2019-2032)
Figure 7: Market Size of BOMEDEMSTAT (IMG-7289) in United Kingdom, in USD million (2019-2032)
Figure 8: Market Size of BOMEDEMSTAT (IMG-7289) in Japan, in USD million (2019-2032)