Brody's Human Pharmacology is a well-established and much-loved textbook that guides students of medicine, pharmacology and other health professions through pharmacology from both basic and clinical perspectives.
What can be a very difficult and complex topic is divided into easily digestible chapters, each of which is clearly structured from a therapeutic overview to mechanisms of action, relationships to clinical responses, pharmacokinetics, pharmacovigilance, new developments, and clinical relevance for all health professionals.
Contains all the essential aspects of pharmacology - suitable for exam preparation
Full color illustrations explain important processes and color-coded boxes enhance understanding
Therapeutic overviews, clinical problems and trade names - everything you need to know
Self-assessment questions and further reading to reinforce learning
Current developments for each class of drugs and how information relates to students in the healthcare professions bring learning to life
Updated content throughout
Pharmacodynamics chapter revised to include discussions of positive and negative allosteric modulators, as well as biased agonism
Pharmacogenetics chapter considers genetic variations and their relationship to drug responses
Section on cancer drugs revised to reflect major advances
New chapter on immunological and cell-based therapies
Table of Contents
Section 1 Mechanisms of Drug Action and Therapeutic Principles 1. Introduction Susan L. Ingram and Lynn Wecker 2. Pharmacodynamics: Receptors and Concentration-Response Relationships JoAnn Trejo, Laura M. Bohn and James Carlton Garrison II 3. Pharmacokinetics Namandje Bumpus and Paul Frederick Hollenberg 4. Pharmacogenomics Larisa Cavallari, Scott A. Mosley and Emily J. Cicali 5. Drug Discovery, Development and Regulation Felix Kim, Lance McMahon, James Barrett, Samuel Obeng and Christopher R. McCurdy Section 2 Chemical Mediators and Drugs Affecting Autonomic and Neuromuscular Synapses 6. Introduction to the Autonomic Nervous System Marsha L. Pierce and Lynn Wecker Cholinergic Drugs 7. Muscarinic Agonists, Cholinesterase Inhibitors and Their Clinical Uses Naoto Hoshi and Frederick J. Ehlert 8. Muscarinic Antagonists and Their Clinical Uses Naoto Hoshi and Frederick J. Ehlert 9. Nicotinic Agonists and Their Clinical Uses Marsha L. Pierce and Lynn Wecker 10. Neuromuscular Blocking Drugs and Nicotinic Antagonists Marsha L. Pierce and Lynn Wecker Adrenergic Drugs 11. Adrenergic Agonists and Their Clinical Uses Javier Cuevas 12. Adrenergic Antagonists and Their Clinical Uses Javier Cuevas Section 3 Drug Treatment for Disorders Affecting the Central Nervous System 13. The Central Nervous System Susan L. Ingram and Lynn Wecker 14. Drug Therapy for Alzheimer's Disease and Other Cognitive Disorders/Dementias Michael S. Jaffee, Steven Trent DeKosky, Meredith Wicklund and Benjamin Albert Chapin 15. Pharmacotherapy of Basal Ganglia Disorders: Parkinson Disease and Huntington Disease Samba Reddy and Juan R. Sanchez-Ramos 16. Drug Therapy for Psychoses and Bipolar Disorder Glenn Catalano, Deborah L. Sanchez, Lynn Wecker and Cory M. Klippel 17. Drug Therapy for Depression and Anxiety Glenn Catalano, Deborah L. Sanchez, Lynn Wecker and Greg Sullivan 18. Drug Therapy for the Management of Attention Deficit-Hyperactivity Disorder Samba Reddy 19. Drug Therapy for Insomnia and the Hypersomnias Miranda Lim and Lynn Wecker 20. Drug Therapy for Managing Obesity and Eating Disorders Charles Rudick 21. Treatment of Seizure Disorders Michael A. Rogawski 22. Drug Therapy for Spasticity Disorders Samba Reddy 23. Ethanol, Other Alcohols and Drugs for Alcohol Use Disorder Jesse D. Hinckley and christian J. Hopfer 24. Illicit Psychoactive Compounds and Substance Use Disorder Jeffrey S. Block and Rex M. Philpot Section 4 Drug Therapy for Pain Management 25. Introduction Susan L. Ingram 26. General Anesthetics Jeffrey J. Pasternak and Tasha L. Welch 27. Local Anesthetics Guy Weinberg and Joshua Edwards 28. Opioid Analgesics Susan L. Ingram and Elena Bagley 29. Nonsteroidal Anti-inflammatory Agents and Acetaminophen Jennelle Durnett Richardson and Jill Fehrenbacher 30. Cannabinoids as Analgesics Jeffrey S. Block, Rex M. Philpot and Lynn Wecker 31. Drug Therapy for Migraine Headache Samba Reddy Section 5 Treatment of Inflammatory, Allergic and Immunologic Disorders 32. Drug Therapy for Gout and Hyperuricemia Angelo Gaffo and Keith Elmslie 33. Drug Therapy for Allergic Reactions Annette Gilchrist and Angela Karash 34. Immunosuppressants for Autoimmune Disorders and Organ Transplantation Kymberly Gowdy, Mythili Chunduru and Jennifer Anne Ferrante 35. Drug Therapy for Rheumatoid Arthritis Michelle Jane Ormseth and Keith Elmslie Section 6 Drug Treatment for Cardiovascular Diseases 36. Introduction to the Regulation of Cardiovascular Function Beth A. Habecker, David A. Taylor, Abdel A. Abdel-Rahman and Steven E. Mansoor 37. Overview of Hypertension Management and Drugs That Decrease Sympathetic Tone James A. McCormick, David A. Taylor and Abdel A. Abdel-Rahman 38. Diuretics and Drugs That Affect Volume and Electrolyte Content James A. McCormick and Abdel A. Abdel-Rahman 39. Drugs Affecting the Renin-Angiotensin- Aldosterone System Vardan T. Karamyan and Abdel A. Abdel-Rahman 40. Calcium Channel Blockers Kelly Karpa and Ryan Wilson 41. Vasodilators for Hypertensive Crises, Pulmonary Hypertension and Erectile Dysfunction David Anthony Tulis and David S. Middlemas 42. Drug Therapy for Hyperlipidemias and Atherosclerotic Cardiovascular Disease Dan F. McCune, Michael T. Piascik and Robert Hadley 43. Drug Therapy for Myocardial Ischemia and Angina Pectoris David A. Taylor and J. West Paul 44. Treatment of Heart Failure Ashley Guillory, Michael T. Piascik and Robert Hadley 45. Antiarrhythmic Drugs David A. Taylor and Stephanie W. Watts 46. Anticoagulant, Antiplatelet and Fibrinolytic Medications Paul T. Kocis, Francis Herrmann, Kelly Karpa and Kent E. Chair 47. Drug Therapy for Hemophilia and the Deficiency Anemias Pamela E. Potter and David A. Taylor Section 7 Treatment of Endocrine Disorders 48. Introduction to Endocrine Pharmacology James J. O'Donnell III 49. Treatment of Hypothalamic and Pituitary Disorders Gerald B. Call and James J. O'Donnell III 50. The Pharmacology of Adrenocorticosteroid Disorders James J. O'Donnell III and Gerald B. Call 51. Female Hormone Regulation David S. Middlemas and Julia Ousterhout 52. Androgens, Antiandrogens, and Their Clinical Uses David S. Middlemas 53. Drug Therapy for the Management of Diabetes Phillip Kopf and Julio A. Copello 54. Drug Therapy for the Management of Thyroid Disorders James J. O'Donnell III and Gerald B. Call 55. Calcium Regulating Hormones and Other Agents Affecting Bone James J. O'Donnell III and Gerald B. Call Section 8 Chemotherapy Infectious Diseases 56. Principles of Antimicrobial Use Rukiyah Van Dross-Anderson and Eman Soliman 57. Drugs Targeting Bacterial Cell Walls and Membranes Rukiyah Van Dross-Anderson and Daniel Ladin 58. Drugs Targeting Bacterial Protein Synthesis Rukiyah Van Dross-Anderson and Daniel Ladin 59. Drugs Targeting Bacterial DNA Rukiyah Van Dross-Anderson and Eman Soliman 60. Antimycobacterial Agents Rukiyah Van Dross-Anderson and Eman Soliman 61. Drug Targeting Resistant Organisms Rukiyah Van Dross-Anderson and Daniel Ladin Parasitic Diseases 62. Antifungal Agents Mona McConnaughey 63. Antimalarial and Other Antiprotozoal Agents Joseph Stone Doggett and Michael Conte 64. Antihelmintics and Ectoparasiticides Mona McConnaughey Viruses 65. Antiviral Agents Susan L. Ingram 66. Antiretroviral Drugs for HIV Amy Wecker Cancer 67. Principles of Antineoplastic Drug Use Stephanie Huang, John Stephen Lazo, Yingbo Huang and Robert Gruener 68. Cytotoxic Agents Jian-Ting Zhang, Amit K. Tiwari and Mary-Ann Bjornsti 69. Targeted Anticancer Agents Jian-Ting Zhang, Amit K. Tiwari and Jill Marie Siegfried 70. Immunological and cell-based therapies Ahmad Tarhini, Turkan Ozturk Topcu and Iyad Kobeissi Section 9 Special Considerations 71. Therapeutic Use of Hematopoietic Growth Factors Pamela E. Potter 72. Gastrointestinal Disorders and Their Treatment Phillip Kopf 73. Pharmacological Treatment of Asthma and COPD Annette Gilchrist and Angela Karash 74. The Role of Neutraceuticals and Natural Products Robert C. Speth and Pamela E. Potter 75. Essentials of Toxicology Monica Valentovic, Lauren Aleksunes and Gary Rankin 76. Therapeutic Considerations for Pregnant, Pediatric, Geriatric and Obese Individuals Susan L. Ingram
Authors
Lynn Wecker Distinguished University Professor, Departments of Psychiatry and Behavioral Medicine and Molecular Pharmacology and Physiology, Director, Laboratory of Neuropsychopharmacology, USF College of Medicine, Tampa, Florida.
Professor Lynn Wecker has recently retired from teaching at USF College of Medicine Tampa Florida, and has agreed to stay on for a final edition to help Susan learn the ropes.
Susan L. Ingram Professor of Neurological Surgery, School of Medicine, Oregon Health & Science University, Portland, Oregon.
Professor Susan Ingram is a Professor of Neurological Surgery at Oregon University, she is a contributor on the 6th edition and has worked with Lynn on various projects over the years.
