The Asia Pacific Tangential Flow Filtration Market should witness market growth of 12.0% CAGR during the forecast period (2022-2028).
The burden of various diseases and disorders is rising continuously, which has propelled the pace of therapeutic research and development worldwide. A significant number of studies are also being done for the development of effective non-viral gene delivery vehicles. Particular emphasis is given to the plasmid DNA (pDNA) nanoparticles that are synthesized with linear polyethylenimine (IPEI) through complexation as a non-viral gene delivery vehicle.
But the lack of reproducible and scalable production methods and the high levels of toxicity have prevented the clinical translation of these nanoparticles. It has been hypothesized that incorporating the incorporation of TFF based purification method would help increment the pDNA’s biocompatibility by reducing the concentration of uncomplexed IPEI present in the nanoparticle formulations.
So far, the optimized procedures have obtained a reduction of about 60% in the uncomplexed IPEI concentration while also maintaining the nanoparticle morphology and size. TFF also aids in the progressive exchange of solvents to other isotonic solutions, thereby increasing the concentration of nanoparticles for injection.
The rising incidences of chronic diseases and ailments have burdened various governments and governmental organizations with developing appropriate counter mechanisms. As a result, the utilization of filtration techniques in pharmaceuticals and biopharmaceuticals has increased significantly. In addition, increasing healthcare expenditure, improving hospital care and infrastructure, and growing regional research and development initiatives are considerably propelling the usage of tangential flow filtration.
The China market dominated the Asia Pacific Tangential Flow Filtration Market by Country in 2021, and would continue to be a dominant market till 2028; thereby, achieving a market value of $256.7 million by 2028. The Japan market is estimated to grow a CAGR of 11.3% during (2022-2028). Additionally, The India market would experience a CAGR of 12.6% during (2022-2028).
Based on Technology, the market is segmented into Microfiltration, Ultrafiltration, and Nanofiltration & Others. Based on Product, the market is segmented into Membrane Filters (Polyethersulfone (PES), Polyvinylidene Difluoride (PVDF), Polytetrafluoroethylene (PTFE), Mixed Cellulose Ester & Cellulose Acetate, Polycarbonate Tracked Etched (PCTE), and Regenerated Cellulose & Others), Single-use, Reusable, and Filtration Accessories. Based on Application, the market is segmented into Protein Purification, Antibody Purification, Vaccine & Viral Vectors, Raw Material Filtration, and Others. Based on End-user, the market is segmented into Pharmaceutical & Biotechnology Companies, CROs & CMOs, and Academic & Research Institutes. Based on countries, the market is segmented into China, Japan, India, South Korea, Singapore, Malaysia, and Rest of Asia Pacific.
The market research report covers the analysis of key stakeholders of the market. Key companies profiled in the report include Parker Hannifin Corporation, Danaher Corporation, Sartorius Stedim Biotech S.A. (Sartorius AG), Merck Millipore (Merck Group), Alfa Laval AB, Repligen Corporation, Meissner Filtration Products, Inc., ABEC, Inc., Sterlitech Corporation, and Synder Inc.
The burden of various diseases and disorders is rising continuously, which has propelled the pace of therapeutic research and development worldwide. A significant number of studies are also being done for the development of effective non-viral gene delivery vehicles. Particular emphasis is given to the plasmid DNA (pDNA) nanoparticles that are synthesized with linear polyethylenimine (IPEI) through complexation as a non-viral gene delivery vehicle.
But the lack of reproducible and scalable production methods and the high levels of toxicity have prevented the clinical translation of these nanoparticles. It has been hypothesized that incorporating the incorporation of TFF based purification method would help increment the pDNA’s biocompatibility by reducing the concentration of uncomplexed IPEI present in the nanoparticle formulations.
So far, the optimized procedures have obtained a reduction of about 60% in the uncomplexed IPEI concentration while also maintaining the nanoparticle morphology and size. TFF also aids in the progressive exchange of solvents to other isotonic solutions, thereby increasing the concentration of nanoparticles for injection.
The rising incidences of chronic diseases and ailments have burdened various governments and governmental organizations with developing appropriate counter mechanisms. As a result, the utilization of filtration techniques in pharmaceuticals and biopharmaceuticals has increased significantly. In addition, increasing healthcare expenditure, improving hospital care and infrastructure, and growing regional research and development initiatives are considerably propelling the usage of tangential flow filtration.
The China market dominated the Asia Pacific Tangential Flow Filtration Market by Country in 2021, and would continue to be a dominant market till 2028; thereby, achieving a market value of $256.7 million by 2028. The Japan market is estimated to grow a CAGR of 11.3% during (2022-2028). Additionally, The India market would experience a CAGR of 12.6% during (2022-2028).
Based on Technology, the market is segmented into Microfiltration, Ultrafiltration, and Nanofiltration & Others. Based on Product, the market is segmented into Membrane Filters (Polyethersulfone (PES), Polyvinylidene Difluoride (PVDF), Polytetrafluoroethylene (PTFE), Mixed Cellulose Ester & Cellulose Acetate, Polycarbonate Tracked Etched (PCTE), and Regenerated Cellulose & Others), Single-use, Reusable, and Filtration Accessories. Based on Application, the market is segmented into Protein Purification, Antibody Purification, Vaccine & Viral Vectors, Raw Material Filtration, and Others. Based on End-user, the market is segmented into Pharmaceutical & Biotechnology Companies, CROs & CMOs, and Academic & Research Institutes. Based on countries, the market is segmented into China, Japan, India, South Korea, Singapore, Malaysia, and Rest of Asia Pacific.
The market research report covers the analysis of key stakeholders of the market. Key companies profiled in the report include Parker Hannifin Corporation, Danaher Corporation, Sartorius Stedim Biotech S.A. (Sartorius AG), Merck Millipore (Merck Group), Alfa Laval AB, Repligen Corporation, Meissner Filtration Products, Inc., ABEC, Inc., Sterlitech Corporation, and Synder Inc.
Scope of the Study
By Technology
- Microfiltration
- Ultrafiltration
- Nanofiltration & Others
By Product
- Membrane Filters
- Polyethersulfone (PES)
- Polyvinylidene Difluoride (PVDF)
- Polytetrafluoroethylene (PTFE)
- Mixed Cellulose Ester & Cellulose Acetate
- Polycarbonate Tracked Etched (PCTE)
- Regenerated Cellulose & Others
- Single-use
- Reusable
- Filtration Accessories
By Application
- Protein Purification
- Antibody Purification
- Vaccine & Viral Vectors
- Raw Material Filtration
- Others
By End-User
- Pharmaceutical & Biotechnology Companies
- CROs & CMOs
- Academic & Research Institutes
By Country
- China
- Japan
- India
- South Korea
- Singapore
- Malaysia
- Rest of Asia Pacific
Key Market Players
List of Companies Profiled in the Report:
- Parker Hannifin Corporation
- Danaher Corporation
- Sartorius Stedim Biotech S.A. (Sartorius AG)
- Merck Millipore (Merck Group)
- Alfa Laval AB
- Repligen Corporation
- Meissner Filtration Products, Inc.
- ABEC, Inc.
- Sterlitech Corporation
- Synder Inc.
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- Exhaustive coverage
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Table of Contents
Chapter 1. Market Scope & Methodology
Chapter 2. Market Overview
Chapter 3. Asia Pacific Tangential Flow Filtration Market by Technology
Chapter 4. Asia Pacific Tangential Flow Filtration Market by Product
Chapter 5. Asia Pacific Tangential Flow Filtration Market by Application
Chapter 6. Asia Pacific Tangential Flow Filtration Market by End-user
Chapter 7. Asia Pacific Tangential Flow Filtration Market by Country
Chapter 8. Company Profiles
Companies Mentioned
- Parker Hannifin Corporation
- Danaher Corporation
- Sartorius Stedim Biotech S.A. (Sartorius AG)
- Merck Millipore (Merck Group)
- Alfa Laval AB
- Repligen Corporation
- Meissner Filtration Products, Inc.
- ABEC, Inc.
- Sterlitech Corporation
- Synder Inc.
Methodology
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