“Estetrol Emerging Drug Insight and Market Forecast - 2032” report provides comprehensive insights about estetrol for Vasomotor Symptoms in the seven major markets. A detailed picture of the estetrol for vasomotor symptoms in the 7MM, i.e., United States, EU4 (Germany, France, Italy, Spain), the United Kingdom, and Japan, for the study period 2019 -2032 is provided in this report along with a detailed description of the estetrol for vasomotor symptoms. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the estetrol market forecast analysis for vasomotor symptoms in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in vasomotor symptoms.
In bone, vagina, endometrium, brain, and the vascular system, E4 acts in synergy with the endogenous estrogens and provides similar effects. E4, however, exerts much less effects on the liver and the breast than E2 this may reduce some unwanted side effects of endogenous estrogens.Estetrol has a high oral bioavailability and its elimination half-life is approximately 28 hours. Moreover, in contrast to E2, E4 is not metabolized to other active estrogen metabolites.
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Drug Summary
Donesta (Estetrol) is a next generation orally-administrated estetrol-based hormone therapy product. It is the first native Estrogen with Selective action in Tissues. Estetrol is a natural estrogen produced by the human foetus and passing in maternal blood at relatively high levels during pregnancy. It acts as an estrogen in the nucleus by activating the nuclear estrogen receptor α (ERα) and recruiting the same coregulator activators and repressors as estradiol (E2), or estriol (E3) in a pattern very different from the selective estrogen receptor modulators, tamoxifen, or raloxifene.In bone, vagina, endometrium, brain, and the vascular system, E4 acts in synergy with the endogenous estrogens and provides similar effects. E4, however, exerts much less effects on the liver and the breast than E2 this may reduce some unwanted side effects of endogenous estrogens.Estetrol has a high oral bioavailability and its elimination half-life is approximately 28 hours. Moreover, in contrast to E2, E4 is not metabolized to other active estrogen metabolites.
Scope of the Report
The report provides insights into:
- A comprehensive product overview including the estetrol description, mechanism of action, dosage and administration, research and development activities in vasomotor symptoms.
- Elaborated details on estetrol regulatory milestones and other development activities have been provided in this report.
- The report also highlights the estetrol research and development activities in vasomotor symptoms across the United States, Europe and Japan.
- The report also covers the patents information with expiry timeline around estetrol.
- The report contains forecasted sales of for vasomotor symptoms till 2032.
- Comprehensive coverage of the late-stage emerging therapies for vasomotor symptoms.
- The report also features the SWOT analysis with analyst views for estetrol in vasomotor symptoms.
Methodology
The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by the research team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.Estetrol Analytical Perspective
In-depth Estetrol Market Assessment
This report provides a detailed market assessment of estetrol for vasomotor symptoms in the seven major markets, i.e., United States, EU4 (Germany, France, Italy, Spain), the United Kingdom), and Japan. This segment of the report provides forecasted sales data from 2024 to 2032.Estetrol Clinical Assessment
The report provides the clinical trials information of estetrol for vasomotor symptoms covering trial interventions, trial conditions, trial status, start and completion dates.Report Highlights
- In the coming years, the market scenario for vasomotor symptoms is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
- The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence estetrol dominance.
- Other emerging products for vasomotor symptoms are expected to give tough market competition to estetrol and launch of late-stage emerging therapies in the near future will significantly impact the market.
- A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of estetrol in vasomotor symptoms.
- This in-depth analysis of the forecasted sales data of estetrol from 2024 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the estetrol in vasomotor symptoms.
Key Questions Answered
- What is the product type, route of administration and mechanism of action of estetrol?
- What is the clinical trial status of the study related to estetrol in vasomotor symptoms and study completion date?
- What are the key collaborations, mergers and acquisitions, licensing and other activities related to the estetrol development?
- What are the key designations that have been granted to estetrol for vasomotor symptoms?
- What is the forecasted market scenario of estetrol for vasomotor symptoms?
- What are the forecasted sales of estetrol in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan?
- What are the other emerging products available and how are these giving competition to estetrol for vasomotor symptoms?
- Which are the late-stage emerging therapies under development for the treatment of vasomotor symptoms?
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Table of Contents
1. Report Introduction2. Estetrol Overview in Vasomotor Symptoms
2.1. Product Detail
2.2. Clinical Development
2.2.1. Clinical studies
2.2.2. Clinical trials information
2.2.3. Safety and efficacy
2.3. Other Developmental Activities
2.4. Product Profile
3. Competitive Landscape (Marketed Therapies)
4. Competitive Landscape (Late-stage Emerging Therapies)
5. Estetrol Market Assessment
5.1. Market Outlook of Estetrol in Vasomotor Symptoms
5.2. 7MM Market Analysis
5.2.1. Market size of estetrol in the 7MM for vasomotor symptoms
5.3. Country-wise Market Analysis
5.3.1. Market size of estetrol in the United States for vasomotor symptoms
5.3.2. Market size of estetrol in Germany for vasomotor symptoms
5.3.3. Market size of estetrol in France for vasomotor symptoms
5.3.4. Market size of estetrol in Italy for vasomotor symptoms
5.3.5. Market size of estetrol in Spain for vasomotor symptoms
5.3.6. Market size of estetrol in the United Kingdom for vasomotor symptoms
5.3.7. Market size of estetrol in Japan for vasomotor symptoms
6. SWOT Analysis
7. Analysts’ Views
8. Appendix
8.1. Bibliography
8.2. Report Methodology
9. Publisher Capabilities
10. Disclaimer
11. About the Publisher
12. Report Purchase Options
List of Tables
Table 1: Estetrol, Clinical Trial Description, 2022
Table 2: Estetrol, General Description
Table 3: Competitive Landscape (Marketed Therapies)
Table 4: Competitive Landscape (Emerging Therapies)
Table 5: Estetrol Market Size in the 7MM, in USD million (2019-2032)
Table 6: Estetrol Market Size in the US, in USD million (2019-2032)
Table 7: Estetrol Market Size in Germany, in USD million (2019-2032)
Table 8: Estetrol Market Size in France, in USD million (2019-2032)
Table 9: Estetrol Market Size in Italy, in USD million (2019-2032)
Table 10: Estetrol Market Size in Spain, in USD million (2019-2032)
Table 11: Estetrol Market Size in the UK, in USD million (2019-2032)
Table 12: Estetrol Market Size in Japan, in USD million (2019-2032)
List of Figures
Figure 1: Estetrol Market Size in the 7MM, USD million (2019-2032)
Figure 2: Estetrol Market Size in the United States, USD million (2019-2032)
Figure 3: Estetrol Market Size in Germany, USD million (2019-2032)
Figure 4: Estetrol Market Size in France, USD million (2019-2032)
Figure 5: Estetrol Market Size in Italy, USD million (2019-2032)
Figure 6: Estetrol Market Size in Spain, USD million (2019-2032)
Figure 7: Estetrol Market Size in the United Kingdom, USD million (2019-2032)
Figure 8: Estetrol Market Size in Japan, USD million (2019-2032)