Nanotechnology Principles in Drug Targeting and Diagnosis focuses on the nanotechnology principles and mechanisms involved in drug targeting, nano carriers and target interactions associated with particular diseases. The book addresses how phytotherapeutics are effective against solid tumors and how they can be used in designing targeted delivery systems. Also addressed is the use of macrophages as the biomimetic carrier for targeting drugs to different organs. Sections cover the nanotechnology-based concepts in drug targeting, strategies for drug targeting, ways to identify drug carrier-target interaction, the concept of an artificial neural network in identifying drug-target interaction, and more.
The book's final section concentrates on the role of nanotechnology in medical diagnosis, throwing light on nanoscale sensors for the diagnosis of viruses in the bloodstream and biomarkers indicating various cancers. This is an important reference source for materials scientists and pharmaceutical scientists who want to understand how nanotechnology plays an important role in creating more efficient drug targeting and delivery systems.
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Table of Contents
SECTION 1 Drug Targeting: General Principles and Strategies 1. Drug Targeting: Nanotechnology Principles, Future Perspectives and Challenges 2. Identifying Nanocarrier-Target Interaction 3. Artificial Neural Network Based Inference of Drug Target Interactions 4. Macrophage-Mimetic Nanomedicines for the Treatment of Diseases 5. Biopolymer Based Nanosystem for Drug Targeting 6. Pharmacokinetics of Nanomedicine
SECTION 2 Nanotechnology Approaches for Organ/Disease Specific Targeting 7. Targeted Breast Cancer Treatment: Progress and Challenges 8. Nanotechnology Advances for Improved Targeting of Solid Tumors 9. Solid Lipid Nanoparticles: The enhanced and targeted potential treatment of colorectal cancer 10. Targeted Therapy for Aggressive Lung Cancer 11. Molecular Targets for the Treatment of Angina Pectoris 12. Nanocarriers: The enhanced potential treatment of age-related macular degeneration 13. Nanotechnology Based Drug Targeting to Infectious Diseases 14. Nanotechnological strategies for drug delivery and treatment of COVID-19
SECTION 3 Nanotechnology Based Techniques for Medical Diagnosis 15. Nanotechnological tools for the diagnosis and treatment of cancer 16. Nanodiagnostics and Targeted Drug Delivery: Integrated Technologies 17. Classification of clinically actionable Genetic Mutations in cancer patients using ML based precision diagnostics 18. Nanotheranostic Applications in the Detection and Treatment of Cervical Cancer
Authors
Mahendra Rai Visiting Scientist, Nicolaus Copernicus University, Torun, Poland.Professor Mahendra Rai is a UGC-Basic Science Research Faculty Fellow and former head of the Department of Biotechnology, Sant Gadge Baba Amravati University, India. Presently, he is a visiting Scientist at the Department of Microbiology, Nicolaus Copernicus University, Poland. His areas of expertise include microbial biotechnology and nanobiotechnology. Currently, his group's main research interest is green synthesis of metal nanoparticles particularly using fungi and their applications as nanoantimicrobials against pathogenic microbes. Prof. Rai has received several prestigious awards, including the Medini Award by the Government of India. He has been featured in Stanford's list of the top 2% of scientists in nanoscience.
Shagufta Khan Professor, Department of Pharmaceutics, Institute of Pharmaceutical Education and Research, Borgaon, India. Shagufta Khan is Professor in the Department of Pharmaceutics, Institute of Pharmaceutical Education and Research, Borgaon, India. Her areas of research are the development of drug loaded nanocarriers, nasal drug delivery for brain targeting, stability enhancement of hygroscopic and photosensitive drugs, oral controlled drug delivery systems and rapid disintegrating tablets. Aarti Belgamwar Assistant Professor, Shri Vile Parle Kelvani Mandal's Institute of Pharmacy, Dhule, India. Aarti Belgamwar is Assistant Professor in the in Shri Vile Parle Kelvani Mandal's Institute of Pharmacy, Dhule. India.Her research interests are nasal drug delivery for brain targeting, solubility enhancement, polymer modification,oral controlled drug delivery systems, and development of multi-particulate drug delivery system.
