Recent Progress in Pharmaceutical Nanobiotechnology: A Medical Perspective offers a comprehensive exploration of the dynamic field of pharmaceutical nanobiotechnology, focusing on its medical applications. This edited reference serves as a valuable resource for researchers, students, and professionals in various disciplines (pharmacology, biotechnology, clinical medicine and nanotechnology) , providing insights into the latest advancements and practical implications of nanotechnology in the pharmaceutical sector.
The book presents 14 edited and referenced chapters that cover several themes for readers.
General Pharmaceutical Nanobiotechnology:
- Introduction to the interdisciplinary field
- Exploration of nanoscale materials for medical purposes
Nanoparticle Development and Applications:
- Bioinspired Nanomedicines
- Lipid-Based Nanocarriers
- Metallic Nanoparticles and Their Applications
- Nanoparticle Targeting Strategies
- Nanomedicine-Based Therapies for Cancer Stem Cells
Biotechnological Aspects:
- Biotechnological Significance of Exosomes
- Glycoconjugates: Biosynthesis and Functions
Innovative Nanotherapies:
- Novel Nanotechnological Approaches for Glioblastoma
- Biocompatibility of Nanomedicines and Bio Corona
Diagnostic and Sensing Applications:
- Role of Nanoparticular/Nano Vesicular Systems as Biosensors
- In Vitro Applications of Drug-Carrying Nanoparticles in Cell Culture Studies
- In Vivo Imaging Techniques: Bioluminescence and Fluorescence Imaging
Precision Medicine:
- The Role of Nano and Biopharmaceutics in Precision Medicine
Audience
Postgraduate researchers in pharmaceutical biotechnology; pharmacy professionals and academicians
Table of Contents
- Contents
- Foreword
- Preface
- List of Contributors
- Şenay Hamarat Şanlıer, Ayça Erek and Habibe Yılmaz
- Introduction
- Liposomes
- The Role of Dna in Nanomedicine Design
- Monoclonal Antibodies and Related Structures
- Cell and Cell Membrane-Derived Biomimetic Nanomedicines
- Bacteria-Inspired Nanomedicines
- Viral Biomimetic Nanomedicines
- Organelle-Related Nanomedicines
- Nanozymes
- Protein Corona and Nanomedicine
- Concluding Remarks
- References
- Ümmühan Fulden Aydın and Abdullah Tuli
- Introduction
- Liposomes
- Formation and Composition of Liposomes
- Preparation Methods of Liposomes
- Thin-Film Hydration
- Injection
- Reverse-Phase Evaporation
- Detergent Removal
- Freeze-Thaw
- French Pressure Cell
- Microfluidics
- Characterization of Liposomes
- Medical Applications of Liposomes
- Solid Lipid Nanoparticles (Slns)
- Formation and Composition of Slns
- Preparation Methods of Slns
- Hot Homogenization
- Cold Homogenization
- Ultrasonication/High-Speed Homogenization
- Solvent Emulsification-Evaporation
- Solvent Emulsification-Diffusion
- Microemulsion
- Double Emulsion
- Supercritical Fluid
- Spray-Drying
- Characterization of Slns
- Medical Applications of Slns
- Nano-Structured Lipid Carriers (Nlcs)
- Formation and Composition of Nlcs
- Preparation Methods of Nlcs
- Characterization of Nlcs
- Medical Applications of Nlcs
- Concluding Remarks
- References
- Medicine
- Şeref Akay and Sultan Eda Kuş
- Introduction
- Synthesis of Metallic Nanoparticles
- Top-Down
- Milling
- Laser Ablation
- Sputtering
- Nanopatterning/Lithography
- Bottom-Up Methods
- Chemical Reduction
- Sol-Gel Method
- Biogenic Method
- Biomedical Applications of Mnps
- Drug Delivery
- Anticancer Therapy
- Antibacterial and Antiviral Applications
- Concluding Remarks
- References
- Ceren Sarı and Figen Celep Eyüpoğlu
- Introduction
- Brief History of Light Therapy
- Exciting Journey of Photodynamic Therapy
- Development of Photosensitizers
- Light Sources
- Administration of Photosensitizers
- Principles of Photodynamic Therapy
- Cellular Uptake
- Subcellular Distribution and Intracellular Targets
- Lysosomes
- Mitochondria
- Endoplasmic Reticulum
- Biomembranes
- Pdt-Induced Cell Death Pathways
- Apoptosis
- Necrosis
- Autophagy
- Necroptosis
- Paraptosis
- Immunogenic Cell Death
- Pdt-Mediated Immune Response
- Antivascular Effects of Pdt
- Pdt in Cancer Treatment
- Combination With Chemotherapy
- Combination With Radiotherapy
- Combination With Immunotherapy
- Nanoscale Drug Delivery Systems
- Nanoparticles
- Liposomes
- Hydrogels
- Limitations and Future Directions
- Concluding Remarks
- References
- Elvan Bakar, Zeynep Erim and Nebiye Pelin Türker
- Introduction
- Structure and Biogenesis of Exosomes
- Composition of Exosomes
- Function of Exosomes
- The Importance of Exosomes in Healthy Physiological Processes
- And Diseases
- Role of Exosomes in Cancer
- Exosomes in the Tumor Microenvironment
- Role of Exosomes in Metastasis
- Role of Exosomes in Angiogenesis
- Exosome-Mediated Immune Response
- Exosomes in Drug Resistance
- Clinical Applications of Exosomes
- Exosomes as Biomarkers and Their Importance
- Role of Exosomes in Drug Delivery and Strategies
- Therapeutic Strategies Based on Exosomes
- Therapeutic Strategies Based on Exosomes Acting on the Immune System
- Concluding Remarks
- References
- Elvan Bakar, Nebiye Pelin Türker and Zeynep Erim
- Introduction
- Glycoconjugates
- Glycornas
- Glycolipids
- Glycoproteins
- Proteoglycans
- Biosynthesis of Glycoconjugates
- Elongation
- Chain Termination
- Glycosylation Related Enzymes
- Glycosyltransferases
- Sialyltransferases
- Galactosyltransferases
- Fucosyltransferases
- N-Acetylglucosaminetransferases and N-Acetylgalactosaminyltransferases
- Mannosyltransferases
Author
- Habibe Yilmaz
