Molecular Pharmaceutics and Nano Drug Delivery: Fundamentals and Challenges provides a thorough resource for both beginners and established scientists, bringing fundamental knowledge about key challenges of these carriers down to the molecular level. The book satisfies the need of availability of literature at single platform with the detailed knowledge to understand crucial aspects, such as regulatory, clinical, toxicological and the formulation requirements of these carriers. This is a valuable resource for graduates, pharmaceutical researchers and anyone working on aspects of pharmaceutics, molecular pharmaceutics and nano-drug/gene delivery.
So called 'novel drug delivery systems' are numerous, with each having different approaches to their production, characterization and evaluation. The proper understanding of these dosage forms, as well as their critical attributes such as toxicity and regulatory requirements are aspects which researchers should know before they begin working on these carriers. This book provides this critical information.
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Table of Contents
1. Protein and enzyme-based nanoformulationsBiswakanth Kar, Deepak Pradhan, Prativa Biswasroy, Jitu Haldar, Tushar Kanti Rajwar, Vineet Kumar Rai, Goutam Ghosh and Goutam Rath
2. Vaccines and sera
Garima Sahu, Priyanka Kumari and Amit K. Goyal
3. Aptamers and antisense oligonucleotide-based delivery
Fatemeh Yazdian and Amin Janghorbani
4. Monoclonal antibodies: recent development in drug delivery
Sumel Ashique, Prathap Madeswara Guptha, Jovita Kanoujia, Ashish Garg, Afzal Hussain, S. Mohana Lakshmi and Neeraj Mishra
5. Hormonal delivery systems
Shivani Rai Paliwal, Kunjbihari Sulakhiya, Pramod Kumar, Sabyasachi Maiti and Rishi Paliwal
6. Vesicular drug delivery systems: a novel approach in current nanomedicine
Elisabetta Mazzotta, Martina Romeo and Rita Muzzalupo
7. Polymeric micelles in drug delivery and targeting
Anchal Pathak, Teeja Suthar, Gautami Nirbhavane and Keerti Jain
8. Physicochemical characterization of drug delivery systems based on nanomaterials
Viviane Lucia Beraldo-de-Arau�jo, Victo� ria Soares Soeiro, Marcelo Van Vliet Lima, Juliana Souza Ribeiro Costa and Laura de Oliveira-Nascimento
9. Inorganic and metal-based nanoparticles
Gajanan Paul, Ujjwal Gupta, Hinal Shah, Farhan M
10. Dendrimers: promises and challenges in drug delivery
Aadil Sk Khatik, Satish Kurdhane, Sanya Batheja and Umesh Gupta
11. Development of advanced diagnostic platform for detection of infectious diseases
Deepshikha Shahdeo, Drishya Prakashan and Sonu Gandhi
12. Fundamentals of a targeted drug delivery system
Akash Chaurasiya, Sonali Singh, Kanan Panchal, Rishi Paliwal and Akanksha Malaiya
13. Assessment of nanotoxicology through in vitro techniques and image-based assays
Fernanda Garcia-Fossa, Tuanny Leite Almeida, Rafaella Mascarelli Pereira, Thai�s Moraes-Lacerda, Mariana Rodrigues Da Silva, Laura de Oliveira-Nascimento and Marcelo Bispo de Jesus
14. Gene therapy: advocacies, perspectives, and ethical provocations
Rajeev Taliyan, Rajesh Sukhija, Ameya Kothekar, Ansit Mishra, Priyamvada Nair and Shaifali Gurjar