The protein A resin market size has grown strongly in recent years. It will grow from $1.66 billion in 2024 to $1.8 billion in 2025 at a compound annual growth rate (CAGR) of 8.6%. The growth in the historic period can be attributed to increasing biopharmaceutical production, growing adoption of monoclonal antibodies, expanding research and development activities, regulatory emphasis on biopharmaceutical quality, rising prevalence of chronic diseases.
The protein A resin market size is expected to see rapid growth in the next few years. It will grow to $2.66 billion in 2029 at a compound annual growth rate (CAGR) of 10.3%. The growth in the forecast period can be attributed to rising biosimilar development, focus on cost-efficiency, increasing investment in bioprocessing facilities, expansion of biopharmaceutical market in emerging economies, growing demand for personalized medicine. Major trends in the forecast period include single-use systems, technological advancements, demand in emerging markets, strategic collaborations and partnerships, focus on sustainable practices.
The anticipated increase in R&D investments within pharmaceutical companies is poised to drive the growth of the protein A resin market. Research and Development (R&D) involve the exploration and creation of new drugs, therapies, technologies, or services aimed at enhancing patient health. Protein A resin is a crucial component in chromatography assays utilized during pharmaceutical development processes. In 2022, Roche Holding AG, a Switzerland-based pharmaceutical company, set a record by spending $16.79 billion on R&D, marking a 3.7% increase from 2021. Similarly, Merck, a US-based pharmaceutical company, elevated its R&D spending by 10% in 2022, reaching $13.54 billion. Consequently, the heightened R&D investments in pharmaceutical firms are fostering the expansion of the protein A resin market.
The rise in healthcare expenditure is anticipated to drive the growth of the protein A resin market in the future. Healthcare expenditure refers to the total amount allocated for healthcare services, goods, and activities within a specific healthcare system or economy over a particular timeframe. Increased healthcare spending facilitates greater investment in research and development related to protein A resin, fostering innovations, enhancing manufacturing processes, improving efficiency, and driving advancements. This investment ultimately boosts production capabilities, ensures product quality, and enhances the availability of this essential component in biopharmaceutical manufacturing. For example, in May 2024, the Office for National Statistics, a UK-based statistics authority, reported that healthcare expenditure in the UK was approximately £292 billion in 2023, indicating a nominal increase of 5.6%. Furthermore, long-term health and social care spending rose by 2.8% in real terms in 2022. Therefore, the increasing healthcare expenditure is fueling the growth of the protein A resin market.
Major companies in the protein A resin market are prioritizing product innovation, such as high-performance affinity protein A resin, to enhance purification efficiency, lower production costs, and improve overall yield in biopharmaceutical manufacturing. High-performance affinity protein A resin is a specialized chromatography medium designed for the efficient purification of antibodies and other proteins from complex biological mixtures. For example, in July 2024, Purolite, Ltd., a US-based developer, manufacturer, and supplier of resins, launched DurA Cycle A50, a new affinity protein A resin aimed at enhancing downstream purification in the biologics sector. This innovative resin features an extended lifespan, reduced ligand leakage, and high performance, offering a cost-effective solution for antibody purification. The product launch addresses key industry challenges, such as reducing costs and ensuring supply chain security through dual sourcing, thereby increasing efficiency for customers.
Major companies in the protein resin market are focusing on developing high-reliability technologies, including polymer technology, to boost productivity and tackle the specific challenges of purifying complex biomolecules in biopharmaceutical manufacturing. Polymer technology in protein A resin enhances the performance and stability of resins in chromatography processes for antibody purification, improving binding capacity, chemical resistance, and longevity. For instance, in September 2024, JSR Life Sciences, a US-based company that develops and manufactures various biomedical materials, launched Amsphere A+, a next-generation protein A chromatography resin designed to improve antibody drug purification. This new resin offers superior binding capacity, stability, and efficiency compared to its predecessor, Amsphere A3. The innovation aims to support the increasing complexity of antibody drug production, particularly for bispecific antibodies and antibody-drug conjugates, utilizing a proprietary protein ligand and advanced polymer technology to enhance production efficiency.
In April 2023, Sino Biological, a China-based company specializing in recombinant protein production and antibody development, acquired SignalChem Biotech Inc. for $48 million. This acquisition aims to enhance Sino Biological’s expertise in bioactive enzyme production, which is crucial for advancing drug discovery and development, and to expand its product range and research services. By leveraging specialized enzyme platforms, Sino Biological seeks to better serve the global life sciences community. SignalChem Biotech Inc. is a Canada-based company focused on the research, development, and production of innovative and high-quality human recombinant cell signaling products.
Major companies operating in the protein A resin market include GenScript Biotech Corporation, Agilent Technologies Inc., Repligen Corporation, Thermo Fisher Scientific Inc., Bio-Rad Laboratories Inc., Abcam plc, Novasep Holdings SAS, GE Healthcare Technologies Inc., Merck KGaA, Tosoh Bioscience LLC, Purolite Corporation, Kaneka Corporation, JSR Life Sciences Corporation, Danaher Corporation, Avantor Inc., Global Life Sciences Solutions USA, EMD Millipore Corp., Bio-Works Technologies AB, Avantor Performance Materials LLC, Avacta Life Sciences Limited, Purolite Lifesciences.
North America was the largest region in the Protein A Resin market in 2024. Europe is expected to be the fastest-growing region in the protein A resin market report during the forecast period. The regions covered in the protein a resin market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the protein a resin market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
Protein A resin is a type of chromatography resin widely utilized in protein purification processes, particularly for the purification of antibodies and monoclonal antibody products.
The main types of protein A resins include natural protein A and recombinant protein A. Natural protein A is a high-efficiency chromatography medium produced in the bacteria Staphylococcus aureus. The matrix types involved in protein A resins are agarose-based protein A, glass/silica-based protein A, and organic polymer-based protein A. These resins find applications in various processes, including antibody purification and immunoprecipitation. Protein A resins are commonly employed by biopharmaceutical manufacturers, clinical research laboratories, and academic institutes.
The protein A resin market research report is one of a series of new reports that provides protein A resin market statistics, including protein A resin industry global market size, regional shares, competitors with a protein A resin market share, detailed protein A resin market segments, market trends, and opportunities, and any further data you may need to thrive in the protein A resin industry. This protein A resin market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The protein A resin market consists of sales of fiber-based fibro prismA units, agarose-based protein A, and ion exchange chromatography resins. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
This product will be delivered within 3-5 business days.
The protein A resin market size is expected to see rapid growth in the next few years. It will grow to $2.66 billion in 2029 at a compound annual growth rate (CAGR) of 10.3%. The growth in the forecast period can be attributed to rising biosimilar development, focus on cost-efficiency, increasing investment in bioprocessing facilities, expansion of biopharmaceutical market in emerging economies, growing demand for personalized medicine. Major trends in the forecast period include single-use systems, technological advancements, demand in emerging markets, strategic collaborations and partnerships, focus on sustainable practices.
The anticipated increase in R&D investments within pharmaceutical companies is poised to drive the growth of the protein A resin market. Research and Development (R&D) involve the exploration and creation of new drugs, therapies, technologies, or services aimed at enhancing patient health. Protein A resin is a crucial component in chromatography assays utilized during pharmaceutical development processes. In 2022, Roche Holding AG, a Switzerland-based pharmaceutical company, set a record by spending $16.79 billion on R&D, marking a 3.7% increase from 2021. Similarly, Merck, a US-based pharmaceutical company, elevated its R&D spending by 10% in 2022, reaching $13.54 billion. Consequently, the heightened R&D investments in pharmaceutical firms are fostering the expansion of the protein A resin market.
The rise in healthcare expenditure is anticipated to drive the growth of the protein A resin market in the future. Healthcare expenditure refers to the total amount allocated for healthcare services, goods, and activities within a specific healthcare system or economy over a particular timeframe. Increased healthcare spending facilitates greater investment in research and development related to protein A resin, fostering innovations, enhancing manufacturing processes, improving efficiency, and driving advancements. This investment ultimately boosts production capabilities, ensures product quality, and enhances the availability of this essential component in biopharmaceutical manufacturing. For example, in May 2024, the Office for National Statistics, a UK-based statistics authority, reported that healthcare expenditure in the UK was approximately £292 billion in 2023, indicating a nominal increase of 5.6%. Furthermore, long-term health and social care spending rose by 2.8% in real terms in 2022. Therefore, the increasing healthcare expenditure is fueling the growth of the protein A resin market.
Major companies in the protein A resin market are prioritizing product innovation, such as high-performance affinity protein A resin, to enhance purification efficiency, lower production costs, and improve overall yield in biopharmaceutical manufacturing. High-performance affinity protein A resin is a specialized chromatography medium designed for the efficient purification of antibodies and other proteins from complex biological mixtures. For example, in July 2024, Purolite, Ltd., a US-based developer, manufacturer, and supplier of resins, launched DurA Cycle A50, a new affinity protein A resin aimed at enhancing downstream purification in the biologics sector. This innovative resin features an extended lifespan, reduced ligand leakage, and high performance, offering a cost-effective solution for antibody purification. The product launch addresses key industry challenges, such as reducing costs and ensuring supply chain security through dual sourcing, thereby increasing efficiency for customers.
Major companies in the protein resin market are focusing on developing high-reliability technologies, including polymer technology, to boost productivity and tackle the specific challenges of purifying complex biomolecules in biopharmaceutical manufacturing. Polymer technology in protein A resin enhances the performance and stability of resins in chromatography processes for antibody purification, improving binding capacity, chemical resistance, and longevity. For instance, in September 2024, JSR Life Sciences, a US-based company that develops and manufactures various biomedical materials, launched Amsphere A+, a next-generation protein A chromatography resin designed to improve antibody drug purification. This new resin offers superior binding capacity, stability, and efficiency compared to its predecessor, Amsphere A3. The innovation aims to support the increasing complexity of antibody drug production, particularly for bispecific antibodies and antibody-drug conjugates, utilizing a proprietary protein ligand and advanced polymer technology to enhance production efficiency.
In April 2023, Sino Biological, a China-based company specializing in recombinant protein production and antibody development, acquired SignalChem Biotech Inc. for $48 million. This acquisition aims to enhance Sino Biological’s expertise in bioactive enzyme production, which is crucial for advancing drug discovery and development, and to expand its product range and research services. By leveraging specialized enzyme platforms, Sino Biological seeks to better serve the global life sciences community. SignalChem Biotech Inc. is a Canada-based company focused on the research, development, and production of innovative and high-quality human recombinant cell signaling products.
Major companies operating in the protein A resin market include GenScript Biotech Corporation, Agilent Technologies Inc., Repligen Corporation, Thermo Fisher Scientific Inc., Bio-Rad Laboratories Inc., Abcam plc, Novasep Holdings SAS, GE Healthcare Technologies Inc., Merck KGaA, Tosoh Bioscience LLC, Purolite Corporation, Kaneka Corporation, JSR Life Sciences Corporation, Danaher Corporation, Avantor Inc., Global Life Sciences Solutions USA, EMD Millipore Corp., Bio-Works Technologies AB, Avantor Performance Materials LLC, Avacta Life Sciences Limited, Purolite Lifesciences.
North America was the largest region in the Protein A Resin market in 2024. Europe is expected to be the fastest-growing region in the protein A resin market report during the forecast period. The regions covered in the protein a resin market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the protein a resin market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
Protein A resin is a type of chromatography resin widely utilized in protein purification processes, particularly for the purification of antibodies and monoclonal antibody products.
The main types of protein A resins include natural protein A and recombinant protein A. Natural protein A is a high-efficiency chromatography medium produced in the bacteria Staphylococcus aureus. The matrix types involved in protein A resins are agarose-based protein A, glass/silica-based protein A, and organic polymer-based protein A. These resins find applications in various processes, including antibody purification and immunoprecipitation. Protein A resins are commonly employed by biopharmaceutical manufacturers, clinical research laboratories, and academic institutes.
The protein A resin market research report is one of a series of new reports that provides protein A resin market statistics, including protein A resin industry global market size, regional shares, competitors with a protein A resin market share, detailed protein A resin market segments, market trends, and opportunities, and any further data you may need to thrive in the protein A resin industry. This protein A resin market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The protein A resin market consists of sales of fiber-based fibro prismA units, agarose-based protein A, and ion exchange chromatography resins. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
This product will be delivered within 3-5 business days.
Table of Contents
1. Executive Summary2. Protein a Resin Market Characteristics3. Protein a Resin Market Trends and Strategies4. Protein a Resin Market - Macro Economic Scenario Including the Impact of Interest Rates, Inflation, Geopolitics, and the Recovery from COVID-19 on the Market32. Global Protein a Resin Market Competitive Benchmarking and Dashboard33. Key Mergers and Acquisitions in the Protein a Resin Market34. Recent Developments in the Protein a Resin Market
5. Global Protein a Resin Growth Analysis and Strategic Analysis Framework
6. Protein a Resin Market Segmentation
7. Protein a Resin Market Regional and Country Analysis
8. Asia-Pacific Protein a Resin Market
9. China Protein a Resin Market
10. India Protein a Resin Market
11. Japan Protein a Resin Market
12. Australia Protein a Resin Market
13. Indonesia Protein a Resin Market
14. South Korea Protein a Resin Market
15. Western Europe Protein a Resin Market
16. UK Protein a Resin Market
17. Germany Protein a Resin Market
18. France Protein a Resin Market
19. Italy Protein a Resin Market
20. Spain Protein a Resin Market
21. Eastern Europe Protein a Resin Market
22. Russia Protein a Resin Market
23. North America Protein a Resin Market
24. USA Protein a Resin Market
25. Canada Protein a Resin Market
26. South America Protein a Resin Market
27. Brazil Protein a Resin Market
28. Middle East Protein a Resin Market
29. Africa Protein a Resin Market
30. Protein a Resin Market Competitive Landscape and Company Profiles
31. Protein a Resin Market Other Major and Innovative Companies
35. Protein a Resin Market High Potential Countries, Segments and Strategies
36. Appendix
Executive Summary
Protein a Resin Global Market Report 2025 provides strategists, marketers and senior management with the critical information they need to assess the market.This report focuses on protein a resin market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
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Description
Where is the largest and fastest growing market for protein a resin ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The protein a resin market global report answers all these questions and many more.The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market’s historic and forecast market growth by geography.
- the market characteristics section of the report defines and explains the market.
- the market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
- the forecasts are made after considering the major factors currently impacting the market. These include:
- the forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.
- Market segmentations break down the market into sub markets.
- the regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth. It covers the growth trajectory of COVID-19 for all regions, key developed countries and major emerging markets.
- the competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
- the trends and strategies section analyses the shape of the market as it emerges from the crisis and suggests how companies can grow as the market recovers.
Scope
Markets Covered:
1) by Type: Natural Protein a; Recombinant Protein a2) by Matrix Type: Agarose-Based Protein a; Glass or Silica-Based Protein a; Organic Polymer-Based Protein a
3) by Application: Antibody Purification; Immunoprecipitation
4) by End User: Biopharmaceutical Manufacturers; Clinical Research Laboratories; Academic Institutes
Subsegments:
1) by Natural Protein a: Affinity Chromatography Resins; Protein Purification Resins; IgG Binding Resins2) by Recombinant Protein a: Genetically Engineered Protein a Resins; Modified Protein a Resins; High-Capacity Protein a Resins
Key Companies Mentioned: GenScript Biotech Corporation; Agilent Technologies Inc.; Repligen Corporation; Thermo Fisher Scientific Inc.; Bio-Rad Laboratories Inc.
Countries: Australia; Brazil; China; France; Germany; India; Indonesia; Japan; Russia; South Korea; UK; USA; Canada; Italy; Spain
Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
Time Series: Five years historic and ten years forecast.
Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita.
Data Segmentation: Country and regional historic and forecast data, market share of competitors, market segments.
Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.
Delivery Format: PDF, Word and Excel Data Dashboard.
Companies Mentioned
Some of the major companies featured in this Protein a Resin market report include:- GenScript Biotech Corporation
- Agilent Technologies Inc.
- Repligen Corporation
- Thermo Fisher Scientific Inc.
- Bio-Rad Laboratories Inc.
- Abcam plc
- Novasep Holdings SAS
- GE Healthcare Technologies Inc.
- Merck KGaA
- Tosoh Bioscience LLC
- Purolite Corporation
- Kaneka Corporation
- JSR Life Sciences Corporation
- Danaher Corporation
- Avantor Inc.
- Global Life Sciences Solutions USA
- EMD Millipore Corp.
- Bio-Works Technologies AB
- Avantor Performance Materials LLC
- Avacta Life Sciences Limited
- Purolite Lifesciences
Table Information
Report Attribute | Details |
---|---|
No. of Pages | 200 |
Published | February 2025 |
Forecast Period | 2025 - 2029 |
Estimated Market Value ( USD | $ 1.8 Billion |
Forecasted Market Value ( USD | $ 2.66 Billion |
Compound Annual Growth Rate | 10.3% |
Regions Covered | Global |
No. of Companies Mentioned | 22 |