Translational Bioinformatics is an emerging field in the direction of biomedical research. High throughput technologies can be applied to the generated biological data to develop the vaccine and personalized medicine. This volume consists of the chapters from different stalwart of the field covering the topics such as drug development, vector engineering, vaccine development and translational genomics. Chapters covered in this volume discuss the translational research related with cancer, Alzheimer disease and cardiovascular diseases. This volume includes the chapter describing the importance of computational resources and chemoinformatics for the translational health research. How Omics studies are helping to translate the laboratory data into the development of tools which are beneficial in the clinics have been described. How translational bioinformatics helpful in plant genomics to improve the crops have also been included in this volume. This volume has a chapter which describes the secrets of resistance development and further how these resistance are associated with human infectious diseases. This volume will be useful to the early career researcher in the development of research idea and develop their methodologies in the direction of bioinformatics and it will also give the insight to translate their findings.
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Table of Contents
1. Genome to Clinic: The Power of Translational Bioinformatics in Improving Human HealthVijay Kumar Prapajati
2. Computational approaches for identifying disease causing mutations in proteins
M. Michael Gromiha
3. Genome-based solutions for managing mucormycosis
Gajendra Pal Singh Raghava
4. Nanobioinformatics-based Insights into the Interaction of Blood Plasma Proteins with Carbon-Based Nanomaterials: Implications for Biomedical Applications
Sunil Kumar Singh
5. Computational Resources and Chemoinformatics: Accelerating Translational Health Research
Timir Tripathi and Dev Bukhsh Singh
6. Protein-Protein Interaction Network analysis for the Identification of Novel Multi-target inhibitors and target miRNAs against Alzheimer's disease
Kunal Roy
7. Engineering Immune Response to Regulate Cardiovascular Disease and Cancers
Sanjay Kumar Dey, Shahjahan Shahjahan and Joy Kumar Dey
8. circCodan: A ghmm-based tool for accurate prediction of Coding Regions in circRNA
Alexandre Paschoal and Andr� Yoshiaki Kashibawara
9. Recent advances in plant translational genomics for crop improvement
Rajiv Ranjan
10. Uncovering the Secrets of Resistance: An Introduction to Computational Methods in Infectious Disease Research
Aditya K. Padhi and Shweata Maurya
11. Technological advances in the Design and Optimization of viral vectors for
Vijay Kumar Prapajati
12. A journey from Omics to Clinicomics in Cancer: Success Stories and Challenges
Sanjana Mehrotra
