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Handbook of Proteolytic Enzymes. Metallopeptidases. Edition No. 4. Handbook of Proteolytic Enzymes, Two-Volume Set with CD-ROM

  • Book

  • March 2025
  • Elsevier Science and Technology
  • ID: 5894867
Handbook of Proteolytic Enzymes, Metallopeptidases has stood as most comprehensive work in the field of applied enzymology and biocatalysis since the first edition published in 1998. Extensively revised and updated, the new fourth edition is an essential reference for biochemists, biotechnologists, and molecular biologists across academia and industry. Edited by world-renowned experts in the field, and with five volumes available for individual sale, this work provides detailed information on all known proteolytic enzymes researched to-date, with expanded coverage of metallopeptidases, cysteine peptidases, serine and threonine peptidases, aspartic and glutamic peptidases, and inhibitors of proteolytic enzymes.

This volume includes over 300 chapters on known metallopeptidases enzymes, including their name, history, activity and specificity, structural chemistry, preparation, biological aspects, and distinguishing features, with 2D structures of peptidases in color, extensive references, and links to PubMed and MEROPS databases.

Table of Contents

Volume 1: Metallopeptidases
Volume 2: Serine and threonine peptidases
Volume 3: Cysteine peptidases
Volume 4: Aspartic and glutamic peptidases, asparagine peptide lysases, and peptidases of unknown catalytic mechanisms
Volume 5: Naturally-occurring and synthetic inhibitors of proteolytic enzymes. METALLOPEPTIDASES

Authors

Neil D. Rawlings Senior Scientist, Proteins Department, EMBL-European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK. Currently Dr. Neil Rawlings is a Senior Scientist in the Proteins Department at the EMBL-European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK. Dr. Rawlings has been an active researcher at the Wellcome Trust Sanger Institute for over twenty years. He is extremely well known in the proteolytic enzyme community for his work curating the MEROPS database, an information resource covering peptidases and the proteins that inhibit them, which is used by expert researchers and students worldwide. Dr. Rawlings has published widely in such peer reviewed journals as Genome Research, BMC Bioinformatics, PloS ONE, Nucleic Acids Research, the Journal of Biological Chemistry, and Science. David S. Auld Associate Professor of Pathology, Harvard, MA, USA. David S. Auld is Associate Professor of Pathology at Harvard in MA, USA.