More than 34 million Americans suffer from pathologies of the digestive system, with over 20 million of these disorders chronic. Treatment of these patients is a complex multidisciplinary area of clinical medicine, drawing upon expertise not only from specialist gastroenterologists but also pathologists, immunologists, endoscopists, and more. Morson & Dawson’s Gastrointestinal Pathology has long set the standard for pathology textbooks, with its distinctive balance of clinical gastroenterology and pathology. Now fully updated to reflect the latest research in this vital field of medicine, it promises to bring this subject to a new generation of clinicians and pathologists worldwide.
Readers of the sixth edition of Morson and Dawson’s Gastrointestinal Pathology will also find: - Contemporary recommendations and guidelines for getting the most out of every pathology specimen and producing the best possible report for managing the patient- Discussions of the evolving applications of immunohistochemistry and in situ hybridisation- A completely new chapter on lymphoid and other tumours of the large intestine
Morson & Dawson’s Gastrointestinal Pathology is ideal for gastrointestinal pathologists, general pathologists, gastroenterologists, and any clinicians who work with or in gastrointestinal practice.
Table of Contents
Contributors ix
Foreword xiii
Preface and Acknowledgements xv
About the companion website xvii
Part 1 Oesophagus
1 The normal oesophagus: anatomy, specimen dissection and histology relevant to pathologicalpractice 3
Kaiyo Takubo and Neil A Shepherd
2 Normal embryology, foetal development and developmental abnormalities 13
Kaiyo Takubo and Neil A Shepherd
3 Neuromuscular and mechanical disorders of the oesophagus 21
D Scott A Sanders
4 Inflammatory disorders of the oesophagus 29
Laura Webb Lamps
5 Barrett’s oesophagus 45
Marnix Jansen and Neil A Shepherd
6 Polyps and tumour-like lesions of the oesophagus 61
Jeremy R Parfitt and David K Driman
7 Tumours of the oesophagus 67
Mikhail Lisovsky and Amitabh Srivastava
8 Miscellaneous conditions of the oesophagus 103
Raymond F T McMahon
Part 2 Stomach
9 The normal stomach: anatomy, histology, and specimen dissection relevant to pathological practice111
Shinichi Ban
10 The stomach: normal embryology, foetal development and developmental abnormalities 129
Michio Shimizu and Do-Youn Park
11 Inflammatory disorders of the stomach 135
Won-Tak Choi, Gregory Y Lauwers and Tomas Slavik
12 Polyps and tumour-like lesions of the stomach 195
Paul Kelly and Gregory Y Lauwers
13 Epithelial tumours of the stomach 227
Bence Kõvári, Fátima Carneiro and Gregory Y Lauwers
14 Stromal tumours of the stomach 287
Erinn Downs, Brian P Rubin and John R Goldblum
15 Lymphoid tumours of the stomach 313
Laurence de Leval, Michaël Lévy and Christiane Copie-Bergman
16 Miscellaneous conditions of the stomach 347
Do-Youn Park, Bence Kővári and Michio Shimizu
Part 3 Small Intestine
17 Normal small intestine: anatomy, specimen dissection and histology relevant to pathologicalpractice 361
Philip V Kaye
18 Congenital abnormalities of the small intestine 373
Elise Gradhand and Newton A C S Wong
19 Neuromuscular and mechanical disorders of the small bowel 385
Joanne E Martin and Pascale Capleton Copyrighted Material
20 Inflammatory disorders of the small intestine 397
Karel Geboes and Anne Jouret-Mourin
21 The pathology of malnutrition and malabsorption 463
Ian Brown
22 Vascular disorders of the small intestine 493
Rhonda K Yantiss
23 Polyps and tumour-like lesions of the small intestine 513
Marnix Jansen, Lodewijk A A Brosens and G Johan A Offerhaus
24 Malignant epithelial tumours of the small intestine 525
Aoife J McCarthy and Kieran Sheahan
25 Mesenchymal tumours of the small intestine 551
Elizabeth Montgomery and Kieran Sheahan
26 Lymphoid tumours of the small intestine 579
Laurence de Leval and Govind Bhagat
27 Miscellaneous disorders of the small intestine 607
Joel K Greenson
Part 4 Appendix
28 Normal appendix: anatomy, specimen dissection and histology relevant to pathological practice615
Norman J Carr
29 Inflammatory disorders of the appendix 621
Rhonda K Yantiss
30 Tumours of the appendix 635
Norman J Carr and Mark J Arends
31 Miscellaneous conditions of the appendix 651
David K Worrall and Mark J Arends
Part 5 Large Intestine
32 Normal large intestine: anatomy, specimen dissection and histology relevant to pathologicalpractice 661
Gordon G A Hutchins, Caroline Young, Kate Marks, Nicholas P West and Phil Quirke
33 Embryogenesis and developmental abnormalities (including the anal region) 677
Adrian C Bateman
34 Muscular and mechanical disorders of the large intestine 687
Joanne E Martin
35 Inflammatory disorders of the large intestine 709
Roger M Feakins
36 Vascular disorders of the large intestine 859
Cian Muldoon
37 Polyps, polyposis syndromes and tumour-like lesions of the large intestine 871
Christophe Rosty, Mark L Bettington and Andrew D Clouston
38 Malignant epithelial neoplasms of the large intestine 925
Shaun V Walsh, Kieran Sheahan and Frank A Carey
39 Mesenchymal tumours of the large intestine 969
Jean-François Fléjou
40 Lymphoid tumours of the large intestine 981
Laurence de Leval, Govind Bhagat and Christiane Copie-Bergman
41 Miscellaneous disorders of the large intestine 991
Adrian C Bateman
Part 6 The Anus
42 Normal anal region: anatomy, histology relevant to pathology practice and specimen handling1003
Lai Mun Wang
43 Inflammatory disorders of the anal region 1009
Miriam Mitchison and Marco R Novelli
44 Tumours and tumour-like conditions of the anus 1017
Newton A C S Wong
45 Miscellaneous conditions of the anal region 1045
Manuel Salto-Tellez and Marco R Novelli
Part 7 Peritoneum
46 The normal peritoneum: anatomy and histology 1053
Maurice B Loughrey
47 Inflammatory disorders of the peritoneum 1057
Maurice B Loughrey
48 Tumours and tumour-like lesions of the peritoneum 1073
Norman J Carr and Maurice B Loughrey
49 Miscellaneous conditions of the peritoneum 1095
Maurice B Loughrey
Index 1099
