- Provides a highly visual guide to the skin, hair, and nails, from normal anatomy and histology to pathology, dermatology, and common issues in plastic surgery and wound healing.
- Covers new topics throughout, including infantile hemangiomas, COVID-19, porphyria cutanea tarda, and Muir-Torre syndrome.
- Provides a concise overview of complex information by integrating anatomical and physiological concepts with clinical scenarios.
- Compiles Dr. Frank H. Netter's master medical artistry-an aesthetic tribute and source of inspiration for medical professionals for over half a century-along with new art in the Netter tradition for each of the major body systems, making this volume a powerful and memorable tool for building foundational knowledge and educating patients or staff.
- NEW! An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, make notes and highlights, and have content read aloud.
Table of Contents
SECTION 1 ANATOMY, EMBRYOLOGY, AND PHYSIOLOGY 1.1 Embryology of the Skin 1.2 Normal Skin Anatomy 1.3 Normal Skin Histology 1.4 Skin Physiology: The Process of Keratinization 1.5 Normal Skin Flora 1.6 Vitamin D Metabolism 1.7 Photobiology 1.8 Wound Healing 1.9 Morphology: Lichenification, Plaques, and Fissures 1.10 Morphology: Macules, Patches, and Vesiculopustules SECTION 2 BENIGN GROWTHS 2.1 Acrochordon 2.2 Becker’s Nevus (Smooth Muscle Hamartoma) 2.3 Dermatofibroma (Sclerosing Hemangioma) 2.4 Eccrine Poroma 2.5 Eccrine Spiradenoma 2.6 Eccrine Syringoma 2.7 Ephelides and Lentigines 2.8 Ephelides and Lentigines (Continued) 2.9 Epidermal Inclusion Cyst 2.10 Epidermal Nevus 2.11 Fibrofolliculoma 2.12 Fibrous Papule 2.13 Ganglion Cyst 2.14 Glomus Tumor and Glomangioma 2.15 Hidradenoma Papilliferum 2.16 Hidrocystoma 2.17 Keloid and Hypertrophic Scar 2.18 Leiomyoma 2.19 Lichenoid Keratosis 2.20 Lipoma 2.21 Median Raphe Cyst 2.22 Melanocytic Nevi: Blue Nevi 2.23 Melanocytic Nevi: Common Acquired Nevi and Giant Congenital Melanocytic Nevi 2.24 Melanocytic Nevi: Congenital Nevi 2.25 Milia 2.26 Neurofibroma 2.27 Nevus Lipomatosus Superficialis 2.28 Nevus of Ota and Nevus of Ito 2.29 Nevus Sebaceous 2.30 Osteoma Cutis 2.31 Palisaded Encapsulated Neuroma 2.32 Pilar Cyst (Trichilemmal Cyst) 2.33 Porokeratosis 2.34 Pyogenic Granuloma 2.35 Reticulohistiocytoma 2.36 Seborrheic Keratosis 2.37 Spitz Nevus SECTION 3 MALIGNANT GROWTHS 3.1 Adnexal Carcinoma 3.2 Angiosarcoma 3.3 Basal Cell Carcinoma: Basic Facial Anatomy 3.4 Basal Cell Carcinoma: Clinical and Histologic Evaluation 3.5 Bowen Disease 3.6 Bowenoid Papulosis 3.7 Cutaneous Metastases 3.8 Dermatofibrosarcoma Protuberans 3.9 Mammary and Extramammary Paget Disease 3.10 Kaposi Sarcoma 3.11 Keratoacanthoma 3.12 Melanoma: Mucocutaneous Malignant Melanoma 3.13 Melanoma: Metastatic Melanoma 3.14 Melanoma: Therapeutics 3.15 Merkel Cell Carcinoma 3.16 Mycosis Fungoides: Clinical Subtypes of Cutaneous T-Cell Lymphoma 3.17 Mycosis Fungoides: Histologic Analysis of Cutaneous T-Cell Lymphoma 3.18 Sebaceous Carcinoma 3.19 Squamous Cell Carcinoma: Genital Squamous Cell Carcinoma 3.20 Squamous Cell Carcinoma: Clinical and Histologic Evaluation SECTION 4 RASHES 4.1 Acanthosis Nigricans 4.2 Acne: Vulgaris 4.3 Acne: Variants 4.4 Acne: Keloidalis Nuchae 4.5 Acute Febrile Neutrophilic Dermatosis (Sweet Syndrome) 4.6 Allergic Contact Dermatitis: Morphology 4.7 Allergic Contact Dermatitis: Patch Testing and Type IV Hypersensitivity 4.8 Atopic Dermatitis: Infants and Children 4.9 Atopic Dermatitis: Adolescents and Adults 4.10 Autoinflammatory Syndromes: Pathophysiology 4.11 Autoinflammatory Syndromes: Clinical Manifestations 4.12 Bug Bites: Brown Recluse Spiders and Scabies Mites 4.13 Bug Bites: Arthropods and Diseases They Carry 4.14 Calciphylaxis 4.15 Cutaneous Lupus: Band Test 4.16 Cutaneous Lupus: Systemic Manifestations of Systemic Lupus Erythematosus 4.17 Cutaneous Lupus: Manifestations 4.18 Cutis Laxa 4.19 Dermatomyositis: Manifestations 4.20 Dermatomyositis: Cutaneous and Laboratory Findings 4.21 Disseminated Intravascular Coagulation 4.22 Elastosis Perforans Serpiginosa 4.23 Eruptive Xanthomas: Congenital Hyperlipoproteinemia 4.24 Eruptive Xanthomas: Acquired Hyperlipoproteinemia 4.25 Erythema Ab Igne 4.26 Erythema Annulare Centrifugum 4.27 Erythema Multiforme, Stevens-Johnson Syndrome, and Toxic Epidermal Necrolysis 4.28 Erythema Multiforme, Stevens-Johnson Syndrome, and Toxic Epidermal Necrolysis (Continued) 4.29 Erythema Nodosum 4.30 Fabry Disease 4.31 Fixed Drug Eruption 4.32 Gout: Gouty Arthritis 4.33 Gout: Tophaceous Gout 4.34 Graft-Versus-Host Disease 4.35 Granuloma Annulare 4.36 Graves Disease and Pretibial Myxedema 4.37 Hidradenitis Suppurativa (Acne Inversa) 4.38 Infantile Hemangiomas 4.39 Irritant Contact Dermatitis 4.40 Keratosis Pilaris 4.41 Langerhans Cell Histiocytosis: Presentation in Childhood 4.42 Langerhans Cell Histiocytosis: Eosinophilic Granuloma 4.43 Leukocytoclastic Vasculitis 4.44 Lichen Planus 4.45 Lichen Simplex Chronicus 4.46 Lower Extremity Vascular Insufficiency 4.47 Mast Cell Disease 4.48 Mast Cell Disease: Degranulation Blockers 4.49 Morphea 4.50 Myxedema 4.51 Necrobiosis Lipoidica 4.52 Necrobiotic Xanthogranuloma 4.53 Neutrophilic Eccrine Hidradenitis 4.54 Ochronosis: Metabolic Pathway and Cutaneous Findings 4.55 Ochronosis: Systemic Findings 4.56 Oral Manifestations in Blood Dyscrasias 4.57 Phytophotodermatitis 4.58 Pigmented Purpura 4.59 Pityriasis Rosea 4.60 Pityriasis Rubra Pilaris 4.61 Polyarteritis Nodosa 4.62 Pruritic Urticarial Papules and Plaques of Pregnancy 4.63 Pseudoxanthoma Elasticum 4.64 Psoriasis: Histopathologic Features and Typical Distribution 4.65 Psoriasis: Inverse Psoriasis and Psoriasis in the Genital Area 4.66 Psoriasis: Psoriatic Arthritis 4.67 Radiation Dermatitis 4.68 Reactive Arthritis (Reiter Syndrome) 4.69 Rosacea 4.70 Sarcoid: Cutaneous Manifestations 4.71 Sarcoid: Systemic Manifestations 4.72 Scleroderma (Systemic Sclerosis) 4.73 Seborrheic Dermatitis 4.74 Skin Manifestations of Inflammatory Bowel Disease: Mucocutaneous Manifestations 4.75 Skin Manifestations of Inflammatory Bowel Disease: Cutaneous Manifestations 4.76 Stasis Dermatitis 4.77 Urticaria 4.78 Vitiligo SECTION 5 AUTOIMMUNE BLISTERING DISEASES 5.1 Basement Membrane Zone, Hemidesmosome, and Desmosome 5.2 Basement Membrane Zone, Hemidesmosome, and Desmosome (Continued) 5.3 Bullous Pemphigoid 5.4 Mucous Membrane Pemphigoid 5.5 Dermatitis Herpetiformis 5.6 Epidermolysis Bullosa Acquisita 5.7 Linear Immunoglobulin A Bullous Dermatosis 5.8 Paraneoplastic Pemphigus 5.9 Pemphigus Foliaceus 5.10 Pemphigus Vulgaris SECTION 6 INFECTIOUS DISEASES 6.1 Actinomycosis 6.2 Blastomycosis 6.3 Chancroid 6.4 Coccidioidomycosis 6.5 COVID-19 6.6 Cryptococcosis 6.7 Cutaneous Larva Migrans 6.8 Dermatophytoses: Tinea Faciei and Tinea Corporis 6.9 Dermatophytoses: Tinea Cruris and Tinea Capitis 6.10 Dermatophytoses: Tinea Pedis and Tinea Unguium 6.11 Herpes Simplex Virus: Lesions 6.12 Herpes Simplex Virus: Lesions (Continued) 6.13 Herpes Simplex Virus: Encephalitis 6.14 Histoplasmosis 6.15 Leprosy (Hansen Disease) 6.16 Lice: Clinical Manifestations 6.17 Lice: Clinical Findings and Management 6.18 Lyme Disease 6.19 Lymphogranuloma Venereum 6.20 Meningococcemia: Acute Adrenal Insufficiency (Waterhouse-Friderichsen Syndrome) 6.21 Meningococcemia: Bacterial Meningitis 6.22 Molluscum Contagiosum 6.23 Paracoccidioidomycosis 6.24 Scabies 6.25 Sporotrichosis 6.26 Staphylococcus aureus Skin Infections: Types of Skin Infections 6.27 Staphylococcus aureus Skin Infections: Toxic Shock Syndrome 6.28 Syphilis: Genitalia 6.29 Syphilis: Oral Cavity 6.30 Syphilis: Pregnancy 6.31 Varicella 6.32 Herpes Zoster (Shingles): Clinical Presentation 6.33 Herpes Zoster (Shingles): Varicella Zoster With Keratitis 6.34 Verrucae (Warts): Human Papillomavirus (HPV) Infection 6.35 Verrucae (Warts): Condylomata Acuminata (Genital Warts) SECTION 7 HAIR AND NAIL DISEASES 7.1 Normal Structure and Function of the Hair Follicle Apparatus 7.2 Normal Structure and Function of the Nail Unit 7.3 Alopecia Areata 7.4 Androgenic Alopecia 7.5 Common Nail Disorders: Fingernail Disorders 7.6 Common Nail Disorders: Toenail Disorders 7.7 Common Nail Disorders (Continued) 7.8 Hair Shaft Abnormalities 7.9 Telogen Effluvium and Anagen Effluvium 7.10 Trichotillomania SECTION 8 NUTRITIONAL AND METABOLIC DISEASES 8.1 Beriberi: Sources and Metabolism of Thiamine (Vitamin B1) 8.2 Beriberi: Clinical Manifestations of Dry and Wet Beriberi 8.3 Hemochromatosis 8.4 Metabolic Diseases: Niemann-Pick Disease, von Gierke Disease, and Galactosemia 8.5 Pellagra: Main Sources, Causes, and Skin Findings 8.6 Pellagra: Mucosal and Central Nervous System Manifestations 8.7 Phenylketonuria: Normal and Abnormal Metabolism 8.8 Phenylketonuria: Clinical Manifestations and Hereditary Patterns 8.9 Porphyria Cutanea Tarda 8.10 Scurvy: Dietary Sources of Vitamin C and Classic Cutaneous Manifestations 8.11 Scurvy: Bony and Skin Abnormalities 8.12 Vitamin A Deficiency 8.13 Vitamin K Deficiency and Vitamin K Antagonists: Potential Clinical Consequences of Warfarin Use 8.14 Vitamin K Deficiency and Vitamin K Antagonists: Anticoagulation Effects on the Clotting Cascade 8.15 Wilson Disease SECTION 9 GENODERMATOSES AND SYNDROMES 9.1 Addison Disease 9.2 Amyloidosis 9.3 Basal Cell Nevus Syndrome 9.4 Carney Complex 9.5 Cushing Syndrome and Cushing Disease 9.6 Cushing Syndrome: Pathophysiology 9.7 Down Syndrome 9.8 Ehlers-Danlos Syndrome 9.9 Marfan Syndrome 9.10 Muir-Torre Syndrome 9.11 Neurofibromatosis: Cutaneous Manifestations 9.12 Neurofibromatosis: Cutaneous and Skeletal Manifestations 9.13 Tuberous Sclerosis Selected References Index