Human Organs-on-a-Chip Technology focuses on technology advancement from “organ-on-a-chip”, “multi organs-on-a-chip”, and the newest stage of “human organs-on-a-chip." Chapters investigate the design, simulation studies, device development, and application of microfluidic systems. In addition, they offer expert perspectives on the development of an alternative test system in the biological evaluation of drugs, cosmetics, chemicals, medical devices, and many others. Lastly, the book addresses issues related to the development of microfluidic devices and alternative test systems in biological and biomedical research.
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Table of Contents
1. Basics of Microfluidics technology2. The Physics and Engineering of Flow in Organ on a Chip Devices
3. Importance of Soft lithography
4. Development of microfluidic devices
5. Microfluidics based point of care devices
6. Microfluidics, Organs-on-a-chip and 3D printing
7.Microfluidic platforms: applications and challenges
8. Design and simulation study of Organ-on-a-chip
9. Primary Cell culture for Organ-on-a-chip
10. Vascularisation in organs-on-a-chip
11. Organ-on-a-chip in nanotechnology
12. Organs-on-a-chip in precision medicine
13. Foeto-placental organ-on-a-chip
14. Organs-on-a-chip in drug development
15. Organ-on-a-chip for multianalyte monitoring
16. Organ-on-a-chip for Blood-brain-barrier studies
17. Organs on a chip models for sensor
18. Innovative ‘organs-on-a-chip’ technology for marine drug development
19. Exposure-on-a-chip as a model for inhalation toxicology and pharmacology research
20. Brain-on-chip
21. Recent breakthrough in organ-on-a-chip
22. 3D printed microfluidic chips
23. 3D tissue and Organ-on-a-chip models
24. Vascularisation of organoids in microfluidic chips
25. Multiorgans-on-a-chip: Design and applications
26. Multiorgans-on-a-chip for subacute toxicity
27. Multiorgans-on-a-chip for acute toxicity
28. Human organs-on-a-chip for biological evaluation
29. Human organs-on-a-chip for cancer modelling
