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Optical Coherence Tomography Angiography for Choroidal and Vitreoretinal Disorders - Part 1

  • Book

  • December 2023
  • Bentham Science Publishers Ltd
  • ID: 5921106
This handbook covers Optical Coherence Tomography Angiography (OCT-A) with a specific focus on choroidal and vitreoretinal disorders. It serves as an invaluable resource for teaching and aiding daily clinical decision-making in the field. Book chapters dissect the fundamentals of angiography through OCT, offering guidance on OCT-A and insights into macular perfusional findings across various vitreoretinal and choroidal pathologies. From diabetic retinopathy to autoimmune diseases and neovascularization, the book addresses prevalent vascular entities encountered in routine practice. Furthermore, it explores innovative approaches, including antivascular endothelial growth factor molecules and extended-release delivery devices, contributing significantly to the diagnostic and decision-making processes in clinical and surgical retina care. Each chapter is contributed by experts in the relevant subspecialty.

Key Features:

Practical, patient-centered guide emphasizing a clinical approach.
Demonstrative clinical cases for enhanced understanding.
Evaluation of perfusional indices using noninvasive and noncontact imaging techniques.
High histopathological correlation of structural tissue characterization with microvascular evaluation.
Exploration of new perfusion concepts and their role in disease pathogenesis.

Part 1 of the book focuses on OCT-A principles and applications in ophthalmology. It covers the basics of OCT-A, its contributions to eye disease study and treatment, and a comparative analysis with OCT for choroidal and vitreoretinal diseases. Additional information on nomenclature, normative datasets, and data analysis, presenting indices in different eye conditions is also presented. The emphasis is on macular perfusion in surgically resolved myopic foveoretinal detachment, postoperative evaluation in retinal detachment, and long-term analysis in diabetic retinopathy

Table of Contents

  • Contents
  • Foreword
  • Preface
  • List of Contributors
Chapter 1 Principles of Optical Coherence Tomography Angiography
  • In Ophthalmology
  • Selma Alin Somilleda-Ventura, Dsc
  • Introduction
  • Oct: Optical Principle
  • Oct Image Acquisition and Processing
  • Fundamental Characteristics of the Octa
  • Artifacts
  • 2-D and 3-D Visualization of Octa Data
  • Octa: Quantitative Data
  • Octa Equipment: Features and Applications
  • Variability and Reproducibility Between Octa Equipment
  • Other Oct Technologies and Novel Developments Related to Octa Devices
  • Concluding Remarks
  • Disclaimer
  • List of Abbreviations
  • References
Chapter 2 Contributions of Optical Coherence Tomography
  • Angiography to the Current Study and Treatment of Eye Diseases
  • Jesus H. Gonzalez-Cortes, Alan B. Trevino-Herrera, Alper Bilgic, Sergio E. Hernandez
  • Da Mota, Jesus E. Gonzalez-Cantu, Akin Akyurt and Renata García Franco
  • Introduction
  • History
  • Principles on Image Acquisition and Terminology
  • Performing Proper Oct-Angiography
  • Normal Oct-Angiography and Normal Retinal Vasculature
  • Principles of Quantitative Oct-Angiography
  • Advantages and Limitations of Oct-Angiography
  • Advantages of Oct-Angiography Over Fa
  • Artifacts in Oct-Angiography
  • Overview of Some Clinical Applications of Oct-Angiography In
  • Retinal and Choroidal Disorders Retinal Disorders Retinal Vein
  • Occlusion
  • Retinal Artery Occlusion
  • Acute Macular Neuroretinopathy and Paracentral Acute Middle
  • Maculopathy
  • Diabetic Retinopathy
  • Hypertensive Retinopathy
  • Macular Telangiectasia Type 2
  • Retinal Arterial Macroaneurysm
  • Choroidal Disorders and Outer Retinal Diseases
  • Age-Related Macular Disease
  • Myopic Degeneration
  • Pachychoroidal Disease
  • Central Serous Chorioretinopathy
  • Pachychoroid Neovasculopathy
  • Polypoidal Choroidal Vasculopathy (Aneurysmal Type
  • Neovascularization - At1)
  • Concluding Remarks
  • Disclaimer
  • References
Chapter 3 Optical Coherence Tomography Vs Optical Coherence
  • Tomography Angiography in the Differential Diagnosis of Choroidal
  • And Vitreoretinal Diseases
  • Martin Flores-Aguilar
  • Introduction
  • Inner Retinal Abnormalities
  • Vitreoretinal Interface
  • Macular Telangiectasia (Mactel)
  • Diabetic Retinopathy
  • Nonproliferative Diabetic Retinopathy.
  • Proliferative Diabetic Retinopathy
  • Ischemic Diabetic Maculopathy and Diabetic Macular Edema
  • Retinal Vascular Occlusions
  • Outer Retinal Disorders
  • Neovascular Membranes in Age-Related Macular Degeneration
  • Neovascular Membranes in Myopia
  • Concluding Remarks
  • Disclaimer
  • References
Chapter 4 Nomenclature and Current Indications of Optical
  • Coherence Tomography Angiography in Diseases of the Choroid And
  • Retina
  • Sergio E. Hernandez Da Mota, Jesus H. Gonzalez-Cortes and Renata Garcia-Franco
  • Introduction
  • Current Indications of Oct-A in Retinal and Choroidal Diseases
  • Ischemic Retinopathies
  • Other Retinal Vascular Diseases
  • Other Vascular Retinal Diseases
  • Choroidal and Outer Retina Diseases
  • Age-Related Macular Degeneration
  • Polypoidal Choroidal Vasculopathy
  • Central Serous Chorioretinopathy
  • Myopic Degeneration
  • Selected Retina Tumors
  • Choroidal Hemangioma
  • Retinal Capillary Hemangioblastoma
  • Retinal Cavernous Hemangioma
  • Concluding Remarks
  • List of Abbreviations
  • Disclaimer
  • References
Chapter 5 Normative Perfusion Indices in the Emmetropic Nondiabetic
  • And Healthy Highly Myopic Adult Population
  • Virgilio Lima-Gómez, Md and Miguel A. Quiroz-Reyes, Md
  • Capillary Circulation of the Macula
  • Superficial Capillary Plexus
  • Middle Capillary Plexus
  • Deep Capillary Plexus
  • Emmetropic Non-Diabetic Adult Population
  • Vessel Length Density (Mm-1)
  • Vessel Area Density
  • Foveal Avascular Zone
  • Choroidal Metrics
  • Healthy Highly Myopic Adult Population
  • Vessel Length Density
  • Vessel Area Density
  • Foveal Avascular Zone
  • Choroidal Metrics
  • Concluding Remarks
  • Acknowledgments
  • Disclaimer
  • References
Chapter 6 Normative Perfusion Indices in the Diabetic Population
  • Virgilio Lima-Gómez, Md and Miguel A. Quiroz-Reyes, Md
  • Vessel Changes in Diabetes Before the Onset of Diabetic
  • Retinopathy
  • Vessel Length Density (Mm-1)
  • Vessel Area Density
  • Foveal Avascular Zone
  • Concluding Remarks
  • Acknowledgments
  • Disclaimer
  • References
Chapter 7 Correlation of the Structural and Perfusion Findings In
  • Patients With Surgically Resolved Myopic Foveoretinal Detachment
  • Miguel A. Quiroz-Reyes, Erick A. Quiroz-Gonzalez, Jorge Morales-Navarro, Miguel
  • A. Quiroz-Gonzalez, Ana L. Diazceballos-Garcia, Sanjay Marasini, Mario Carranza-
  • Casas and Virgilio Lima-Gomez
  • Introduction
  • Preoperative Examination of Highly Myopic Eyes
  • Recommended Structural Examinations in Highly Myopic Eyes
  • Macular Surgery in Highly Myopic Eyes With Mf/Frd
  • Comparison of Perfusional and Structural Findings Between Groups
  • Correlations Between Bcva, Ez Defect, Elm Line Defect, and Biomarkers
  • Representative Surgical Cases
  • Surgical Case 1
  • Surgical Case 2
  • Surgical Case 3
  • Surgical Case 4
  • Literature Review and Discussion
  • Concluding Remarks
  • Patient Consent
  • List of Abbreviations
  • Acknowledgments
  • Disclaimer
  • References
Chapter 8 Postoperative Macular Perfusion Evaluation in Eyes With
  • Noncomplicated Retinal Detachment and Macular Involvement
  • Surgically Managed With Primary Vitrectomy
  • José Dalma-Weiszhausz
  • Introduction
  • Concluding Remarks
  • Disclaimer
  • References
Chapter 9 Postoperative Analysis of Macular Perfusional Status In
  • Giant Retinal Tear-Related Retinal Detachments
  • Miguel A. Quiroz-Reyes, Erick A. Quiroz-Gonzalez, Miguel A. Quiroz-Gonzalez,
  • Ahmad R. Alsaber, Sanjay Marasini and Virgilio Lima-Gomez
  • Introduction
  • Preoperative Evaluation of Grt-Related Rrd
  • Ancillary Preoperative and Postoperative Examination of Eyes With Grts
  • Surgical Techniques in Grt-Associated Rrd
  • Characteristics of Eyes
  • General Surgical Findings
  • Postoperative Structural Analysis
  • Long-Term Perfusion Analysis in Grt
  • Representative Surgical Cases
  • Surgical Case 1
  • Surgical Case 2
  • Surgical Case 3
  • Literature Review and Discussion
  • Concluding Remarks
  • Patient Consent
  • List of Abbreviations
  • Acknowledgments
  • Disclaimer
  • References
Chapter 10 Macular Perfusion in Clinically Significant Diabetic
  • Macular Edema and in Different Stages of Diabetic Retinopathy
  • Virgilio Lima-Gómez, Md and Miguel A. Quiroz-Reyes, Md
  • Clinically Significant Diabetic Macular Edema
  • Vessel Density Metrics in Diabetic Retinopathy
  • Faz Parameters
  • Other Changes
  • Octa Metrics in Dme
  • Vessel Length Density (Mm-1)
  • Vessel Area Density
  • Foveal Avascular Zone
  • Concluding Remarks

Author

  • Miguel A. Quiroz-Reyes
  • Virgilio Lima-Gomez