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In Vitro Propagation and Secondary Metabolite Production from Medicinal Plants: Current Trends (Part 1)

  • Book

  • February 2024
  • Bentham Science Publishers Ltd
  • ID: 5960299
This book is a comprehensive review of secondary metabolite production from plant tissue culture. The editors have compiled 12 meticulously organized chapters that provide the relevant theoretical and practical frameworks in this subject using empirical research findings. The goal of the book is to explain the rationale behind in vitro production of secondary metabolites from some important medicinal plants. Biotechnological strategies like metabolic engineering and the biosynthesis, transport and modulation of important secondary metabolites are explained along with research studies on specific plants. In addition to the benefits of secondary metabolites, the book also aims to highlight the commercial value of medicinal plants for pharmaceutical and healthcare ventures.

Topics covered in this part include:

1. Elicitation Strategies and Metabolic Engineering to boost metabolite production with case studies in metabolic engineering with examples of Scaevola Taccada and Catharanthus Roseus.

2. Stress response investigation and the role of glandular trichomes as bio-cell factories

3. Plant growth regulators and rapid regeneration techniques using swift plantlets regeneration and phytochemical characterization

4. Nutraceuticals, antimicrobials, and genomic applications of in vitro cultures with an example of Hassawi rice and its genomics

5. Sustainable approaches for saving endangered medicinal plants

The book caters to a wide readership. It primarily prepares graduate students, researchers, biotechnologists, giving them a grasp of the key methodologies in the secondary metabolite production. It is a secondary reference for support executives, industry professionals, and policymakers at corporate and government levels to understand the importance of plant tissue culture and maximizing its impact in the herbal industry.

Readership

Graduate students and researchers in plant biotechnology courses; industry professionals and policymakers in the herbal industry.

Table of Contents

CHAPTER 1 SECONDARY METABOLITE PRODUCTION THROUGH ELICITATION:
  • BIOTIC, ABIOTIC, MEJA, PGRS AND STRESS SIGNALING IN IMPROVING COMPOUNDS
  • IN SELECT MEDICINAL PLANTS
  • Mehpara Maqsood, A. Mujib, Mir Khusrau and Zahoor A. Kaloo
  • INTRODUCTION
  • ELICITOR
  • Classification of Elicitor
  • Elicitation and Improved Yield in Some Medicinal Plants
  • MECHANISM
  • CONCLUSION
  • REFERENCES
CHAPTER 2 IN VITRO MULTIPLICATION AND METABOLITE VARIATIONS
  • THROUGH GC-MS OF A MEDICINAL PLANT SCAEVOLA TACCADA (GAERTN.) ROXB. 17
  • M. Raseena and A. Yusuf
  • INTRODUCTION
  • MATERIALS AND METHODS
  • Plant Material and Sterilization
  • Culture Medium and Conditions
  • Multiplication of Shoot
  • Rooting and Acclimatization
  • Gas Chromatography - Mass Spectrometry
  • Sample Preparation
  • RESULTS
  • Shoot Initiation
  • Multiple Shoot Induction
  • Rooting and Acclimatization
  • Gas Chromatography - Mass Spectrometry
  • DISCUSSION
  • CONCLUSION
  • REFERENCES
CHAPTER 3 METABOLIC ENGINEERING & SYNTHETIC BIOLOGY OF
  • MONOTERPENOID INDOLE ALKALOIDS PATHWAY IN CATHARANTHUS ROSEUS
  • Vyoma Mistry, Hemant Borase, Abhishek Sharma and Rajesh Arora
  • INTRODUCTION
  • THE MIAs BIOSYNTHETIC PATHWAY
  • METABOLIC ENGINEERING AND SYNTHETIC BIOLOGY: OPERATIONAL
  • CONSTRAINTS AND KEYS
  • MIAs ‘Pathway Genes’ and ‘Transcriptional Factors Metabolic Engineering’
  • MIAs Synthetic Biology of Plant and Microbial Cell Factories
  • CONCLUSION
  • REFERENCES
CHAPTER 4 IMPACT OF ABIOTIC STRESSES ON IN VITRO PRODUCTION OF
  • SECONDARY METABOLITES
  • Inês Mansinhos, Sandra Gonçalves and Anabela Romano
  • INTRODUCTION
  • SECONDARY METABOLITES OF PLANTS
  • BENEFITS OF USING PLANT TISSUE CULTURE FOR SECONDARY METABOLITES
  • PRODUCTION
  • IMPACT OF ABIOTIC STRESS ON IN VITRO PRODUCTION OF SECONDARY
  • METABOLITES
  • Drought
  • Salinity
  • Nutrients Deficiency
  • Ultraviolet Radiation
  • Temperature
  • CONCLUDING REMARKS
  • ABBREVIATIONS
  • ACKNOWLEDGEMENTS
  • REFERENCES
CHAPTER 5 GLANDULAR TRICHOMES: BIO-CELL FACTORIES OF PLANT
  • SECONDARY METABOLITES
  • Pragya Shukla, Archana Prasad, Khushboo Chawda, Gauri Saxena, Kapil D.
  • Pandey and Debasis Chakrabarty
  • INTRODUCTION
  • GLANDULAR TRICHOME: MORPHOLOGY, DEVELOPMENT, SECONDARY
  • METABOLITE ACCUMULATION AND MOLECULAR REGULATION IN SOME
  • IMPORTANT PLANTS
  • Morphology, Occurrence and Biosynthetic Regulation of Metabolites in the Trichome of
  • Some Important Plants
  • Solanum lycopersicum
  • Artemisia annua
  • Helianthus annuus
  • Cannabis sativa
  • Withania somnifera
  • Influence of Biotic/abiotic Stresses on Trichome Development and Metabolite
  • Accumulation
  • Effect of Abiotic Stress on Trichome Physiology and Metabolic Productivity
  • EFFECT OF BIOTIC STRESS ON TRICHOME PHYSIOLOGY AND METABOLITE
  • PRODUCTIVITY
  • Pathogens
  • Insects
  • CONCLUDING REMARKS AND FUTURE PROSPECTIVE
  • ACKNOWLEDGEMENTS
  • REFERENCES
CHAPTER 6 ROLE OF PLANT GROWTH REGULATORS FOR AUGMENTING
  • SECONDARY METABOLITES PRODUCTION IN MEDICINAL PLANTS
  • Harsh Kumar Chauhan, Anil Kumar Bisht and Indra Dutt Bhatt
  • INTRODUCTION
  • PLANT GROWTH REGULATORS (PGRs)
  • Types of PGRs
  • Auxins
  • Cytokinins
  • Gibberellins
  • Ethylene
  • Abscisic Acid (ABA)
  • SECONDARY METABOLITES
  • Terpenes
  • Phenolics
  • Nitrogen and Sulphur-containing Compounds
  • INFLUENCE OF PGRs ON SECONDARY METABOLITES PRODUCTION OF
  • MEDICINAL PLANTS IN PLANT TISSUE CULTURE
  • Effects of Cytokinins on the Alteration of Secondary Metabolites Production
  • Effects of Auxins on the Alteration of Secondary Metabolites Production
  • Effects of GA on the Alteration of Secondary Metabolites Production
  • Effects of ABA on the Alteration of Secondary Metabolites Production
  • Effects of Combinations on the Alteration of Secondary Metabolites Production
  • CONCLUDING REMARKS
  • REFERENCES
CHAPTER 7 HASSAWI RICE (ORYZA SATIVA L.) NUTRACEUTICAL PROPERTIES, IN
  • VITRO CULTURE AND GENOMICS
  • Muneera Q. Al-Mssallem, Krishnananda P. Ingle, Gopal W. Narkhede, S. Mohan
  • Jain, Penna Suprasanna, Gholamreza Abdi and Jameel M. Al-Khayri
  • INTRODUCTION
  • NUTRITIONAL COMPOSITION OF HASSAWI RICE
  • Macronutrients
  • Micronutrients
  • SECONDARY METABOLITES
  • Classification
  • Biological Functions
  • Secondary Metabolites in Rice
  • MEDICINAL AND PHARMACEUTICAL PROPERTIES
  • Antidiabetic Properties
  • Anti-Obesity and Gastrointestinal Activities
  • BREEDING APPROACHES
  • Cultivation and Limitations
  • Breeding Objectives
  • Heterosis Breeding
  • Hybridization
  • Molecular Breeding Potential
  • Marker-Assisted- Selection for Genetic Improvement
  • Potential Impact
  • TISSUE CULTURE APPLICATIONS
  • Mutation
  • In Vitro Response to Stress
  • GENOMICS
  • Genetic Diversity
  • Genetic Engineering
  • Whole Genome Sequence
  • Chloroplast Genome
  • Mitochondrial Genome
  • Quantitative Trait Loci
  • CONCLUSION AND PROSPECTS
  • REFERENCES
CHAPTER 8 IN VITRO RAPID REGENERATION OF PLANTLETS FROM SHOOT TIP
  • EXPLANTS OF ALLAMANDA CATHARTICA L. AND CHARACTERIZATION OF
  • PHYTOCHEMICALS IN REGENERANTS
  • Mehrun Nisha Khanam and Mohammad Anis
  • INTRODUCTION
  • MATERIALS AND METHODS
  • Explants Collection
  • Explant Preparation
  • Media and Culture Condition
  • Shoot Induction and Multiplication
  • Rooting and Acclimatization
  • Sample Collection and Preparation
  • Preparation of Leaf Extract
  • Statistical Analysis
  • RESULTS AND DISCUSSION
  • Effect of Meta-topolin
  • Cytokinin - Auxin Interaction on Shoot Proliferation
  • Effect of Sucrose
  • Rooting and Acclimatization
  • Phytochemical Screening
  • CONCLUSION
  • ABBREVIATIONS
  • REFERENCES
CHAPTER 9 PRODUCTION OF SECONDARY METABOLITES FROM ENDANGERED
  • AND COMMERCIALLY IMPORTANT MEDICINAL PLANTS THROUGH CELL AND
  • TISSUE CULTURE TECHNOLOGY
  • Fadime Karabulut, Mohammad Yaseen Mir and Azra N. Kamili
  • INTRODUCTION
  • IN VİTRO CULTURE AS A SUBSTİTUTE SYSTEM FOR ENHANCEMENT OF PLANT
  • SECONDARY METABOLİTES
  • Traditional Strategies
  • Metabolic Engineering
  • APPROACHES TO MANİPULATE THE CONTENTS OF PLANT SECONDARY
  • METABOLİTES
  • Carbon Source
  • Media Formulation
  • Temperature
  • Agitation
  • Phosphate
  • Nitrogen
  • Plant Growth Hormones
  • Gas Composition
  • Precursor Supplementation
  • Callus Culture System
  • Cell Suspension Cultures
  • Hairy Root Cultures
  • Organ Culture
  • Elicitation: A Biotechnological Tool
  • CONCLUSİON AND FUTURE PROSPECTİVE
  • REFERENCES

Author

  • Mohammad Anis
  • Mehrun Nisha Khanam