The Chemistry Inside Spices & Herbs: Research and Development brings comprehensive information about the chemistry of spices and herbs with a focus on recent research in this field.
Experts in phytochemistry have contributed reviews with the aim to give the reader deep knowledge about phytochemical constituents in herbal plants and their benefits. The contents include reviews on the biochemistry and biotechnology of spices and herbs, herbal medicines, biologically active compounds and their role in therapeutics among other topics. Chapters that highlight natural drugs and their role in different diseases and special plants of clinical significance are also included.
Volume 3 covers several topics: the treatment of Polycystic Ovary Syndrome (PCOS), managing rheumatoid arthritis and related inflammatory conditions, orchid-derived natural flavoring and therapeutic agent Vanillin, Silymarin's utility in treating hepatic diseases, phytochemistry and pharmacological activities of Hygrophila spinosa, pharmacological and chemical aspects of Tulsi, Combretum caffrum as a potential anticancer molecule, and the roles of herbs in treating diabetes.
This book is an ideal resource for scholars (in life sciences, phytomedicine, and natural product chemistry) and general readers who want to understand the importance of herbs, spices and traditional medicine in pharmaceutical R&D and clinical research.
Readership
Scholars in life sciences, phytomedicine and natural product chemistry; general readers who want to understand the importance of herbs, spices and traditional medicine, pharmaceutical R&D and clinical research.
The Chemistry Inside Spices & Herbs: Research and Development brings comprehensive information about the chemistry of spices and herbs with a focus on recent research in this field.
Table of Contents
Chapter 1 Medicinal Plants Including Spices for the Treatment Of Polycystic Ovary Syndrome (PCOS) With a Preclinical-Clinical Perspective and Phytotherapeutic Approaches
- Introduction
- History and Epidemiology of Polycystic Ovary Syndrome
- Etiology and Pathophysiology of Polycystic Ovary Syndrome
- Clinical Findings and Diagnosis of Polycystic Ovary Syndrome
- Effects of Polycystic Ovary Syndrome on Quality of Life
- Pharmacological and Non-Pharmacological Treat-Ment
- Strategies in Polycystic Ovary Syndrome
- The Role of Medicinal Plants in the Treatment of Polycystic
- Ovary Syndrome
- Ethnopharmacological Approach
- In Vitro Studies on Polycystic Ovary Syndrome
- In Vivo Studies on Polycystic Ovary Syndrome
- Preclinical Studies on Extracts
- Preclinical Studies on Bioactive Phytochemicals
- Clinical Studies on Extracts
- Conclusion
- Credit Authorship Contribution Statement
- References
Chapter 2 Herbs and Their Bioactive Compound’s Role in The Management of Rheumatoid Arthritis and Related Inflammatory Conditions
- Introduction
- Natural Compounds Having Anti-Rheumatoid Arthritis Properties
- Fraxinellone
- Brazilin
- Caffeic and Chlorogenic Acid
- Stilbenoids and Resveratrol
- Cinnamic Aldehyde and Eugenol
- Emodin
- Curcumin
- Berberine
- Celastrol
- Ferulic Acid
- Andrographolide
- Asiaticoside a and Madecassoside
- Liquiritin
- Oleanolic Acid Acetate
- Swertiamarin
- Conclusion
- References
Chapter 3 Biochemical, Biosynthetic and Biotechnological Approaches for An Orchid-Derived Natural Flavoring and Therapeutic Agent Vanillin- a Review
- Introduction
- Botanical Account, Lifecycle & General Features
- Distribution and Environmental Effects
- Phytochemical Constituents of Vanilla Bean
- Different Sources of Vanillin
- The ‘Natural Vanillin’
- Chemical Synthesis
- From Lignin
- From Curcumin
- From Ferulic Acid
- From Eugenol
- From Glucose and Sugar
- From Poly(Ethylene Terephthalate) (Pet)
- History and Traditional Usage
- Pharmaceutical and Biotechnological Usage
- Cosmetic Industry
- Food Industry
- Therapeutics
- Antisickling
- Antioxidant
- Anti-Mutagenic and Anticancer
- Hypolipidimic
- Other Properties
- Micropropagation and Its Advantages
- Extraction and Processing Techniques
- Commercial Extraction Process
- Conventional Methods
- Supercritical Fluid Extraction
- Microwave and Ultrasound-Mediated Extraction
- Enzymatic Extraction
- Solid-Phase Extraction
- Dynamics of Microbial Contribution in Vanillin Production
- Conclusion
- Acknowledgments
- References
Chapter 4 Silymarin: a Boon in the Treatment of Hepatic Diseases
- Introduction
- Botany
- Silymarin's Hepatoprotective Mechanisms of Action
- Antifibrotic Effect
- Immunomodulatory Activity
- Anticancer Effect
- Anti-Inflammatory
- Antitoxin Effect
- Recent Research Pertaining to Hepatoprotection
- Silymarin and Liver Disorder
- Silymarin and Carcinoma
- Silymarin and Viral Hepatitis
- Silymarin and Hepatoprotective Effect
- Silymarin and Hepatitis C Virus Infection
- Conclusion and Future Directions
- References
Chapter 5 Phytochemistry and Pharmacological Activities of An Ayurvedic Medicinal Plant, Hygrophila Spinosa
- Introduction
- Introduction to the Genus Hygrophila
- Common Names and Vernacular Names of Hygrophila Spinosa
- Phytochemistry
- Pharmacological Applications
- Antioxidant Activity
- Antitumor and Cytotoxic Activity
- Antiinflammatory Activity
- Antipyretic Activity
- Haematopoietic/Haematinic/Erythropoietic Activity
- Hepatoprotective Activity
- Anthelmintic Activity
- Antimicrobial Activity
- Analgesic Activity
- Diuretic Activity
- Antimotility Activity
- Antidiabetic Activity
- Cns Activity
- Neuroprotective Activity
- Nephroprotective Activity
- Aphrodisiac and Spermatogenic Activity
- Cardioprotective Activity
- Adaptogenic Activity
- Antiosteoporetic Activity
- Toxicological Studies
- Acute Toxicity Study
- Sub-Acute Toxicity Study
- Conclusion
- Acknowledgments
- References
Chapter 6 Diversities of Omnipotent Tulsi: Pharmacological And Chemical Aspects
- Introduction
- Biochemical Diversities of Tulsi
- Pharmacological Diversities of Tulsi
- Immunity Booster Against Pathogenic Infection
- Antifungal and Insecticidal Action
- Antimicrobial Activity of Tulsi
- Hypoglycaemic Action
- Anti-Ulcer Activity
- Anticancer Action
- Antidiarrheal Action
- Bronchodilator Effect
- Neurological Disorder
- Antituberculosis Effect
- Conclusion and Future Perspective
- Authors Contribution
- Acknowledgments
- References
Chapter 7 Combretum Caffrum Confers a Potential Cutting-Edge Anticancer Molecule as Combretastatins
- Introduction
- Biological Activity of Combretastatin
- Anticancer Activity of Ca-4
- Development of Ca-4 Analogues
- Mechanism of Action of Ca-4
- Computer-Aided Drug Design of Combretastatins and Their
- Derivatives
- Structure-Based Drug Design of Combretastatins and Their
- Derivatives
- Ligand-Based Design of Combretastatins and Their Derivatives
- Current Clinical Status of Ca-4 Analogues
- Adverse Effects and Toxicity
- Concluding Remarks
- References
Chapter 8 the Role of Herbs in the Treatment of Diabetes
- Introduction
- Medicinal Herbs
- Herbs That Regulate Insulin Secretion
- Fenugreek (Trigonella Foneum Graecum)
- Cumin (Cuminum Cyminum)
- Tulsi (Ocimum Sanctum)
- Guduchi (Tinospora Cardifolia)
- Ginger (Zingiber Officinale)
- Mustard (Brassica Nigra)
- Curry Leaves (Murraya Koenigii)
- Garlic (Allium Sativum)
- Turmeric (Curcumin Longa)
- Cinnamon (Cinnamomum Zeylanicum)
- Rosemary (Rosmarinus Officinalis L.)
- Chemical Constituents of Herbs Used in the Treatment of Diabetes
- Challenges of Herbal Medicines in India
- Bioavailability, Dietary Intake, and Possible Side Effects
- Marketed Herbal Formulations for Diabetic Treatment
- Conclusion
- References
- Subject Index
Author
- Pankaj Kumar Chaurasia
- Shashi Lata Bharati
- Sunita Singh
