Whole Cell Biocatalysis, a volume in the Foundations and Frontiers of Enzymology series, offers a detailed overview of the process of biocatalysis using whole cells as an alternative to enzyme biocatalysis. The book examines the potential applications and advantages of whole cell biocatalysis, including its use in the production of fine chemicals, renewable energy, and drug discovery and development. Whole cell biocatalysis for large scale production and non-conventional media are also covered. In addition, the latest methods and techniques are investigated, including cell immobilization, permeabilization, synthetic biology, computational metabolic engineering, and molecular genetics.
This book provides a comprehensive summary on whole cell biocatalysis and the latest developments in this emerging field. It is an invaluable reference for researchers working across biochemistry, enzymology, biotechnology, and related fields.
Table of Contents
1. Advantages and new potential applications of whole-cell biocatalysisSergio Huerta-Ochoa
2. Reprogramming microbial cells to improve the production of biopharmaceuticals and fine chemicals
Francisco Fern�ndez, Marcos L�pez-P�rez, Alvaro Lara
3. Mitigation of greenhouse gas emissions from biogas-producing facilities: A novel whole-cell technology platform based on anaerobic oxidation of methane
Ivonne Figueroa Gonz�lez, Guillermo Quijano
4. Computational metabolic engineering using constrained-based modelling and genome-scale metabolic models
Freddy Castillo-Alfonso, Carlos Coello, Roberto Olivares
5. Whole-cell biocatalysis in non-conventional media
Palmerin Dulce Mar�a Palmerin Carre�o
6. Nanostructured Magnetic Systems in Whole-Cell Biocatalysis
A. Palacios, Jose Luis Martinez Hernandez, Mayela Govea-Salas, Anna Ilyina, Rodolfo Ramos-Gonz�lez, Roberto Arredondo-Valdes, Patricia Segura-Ceniseros, Nayra Vi�als, Monica L Chavez
7. Filamentous fungi as biopharmaceutical protein factories
Mar�a Moreno, Ulises Carrasco Navarro
8. Proteomic analysis: application to the study of signal transduction pathways in {i Penicillium chrysogenum }and{i Acremonium chrysogenum}
Ulises Carrasco Navarro, Francisco Fern�ndez, Mar�a Moreno
9. Fungal lipase obtained by surface adhesion fermentation using magnetic chitosan-coated nanoparticles
Patricia Segura-Ceniseros, Cynthia Barrera, Elva Ar�chiga-Carvajal, Anna Ilyina, Rodolfo Ramos-Gonz�lez, Jose Luis Martinez Hernandez
10. Steroid biotransformation by plant cells
Gabriel Alfonso Guti�rrez Rebolledo, Mariana Zuleima P�rez Gonz�lez, Francisco Cruz Sosa, Mariana S�nchez Ramos
11. Whole-cell biocatalysis for large-scale production
Contributors: Zhi-Qiang Liu, Xiao-Jian Zhang, Zheng Yuguo, Zhu Fangying, Ji-Dong Shen, Xue Cai