The series Stem Cell Innovation in Health and Disease is a timely and fascinating collection of information and new discoveries and provides a contemporary snapshot album from the fast-moving field of regenerative medicine and stem cell therapeutics. The Nervous System, Volume 5 addresses the recent data accumulated on the potential applications of stem cells to treat diseases and disorders of the nervous system. This volume will highlight the recent development of cutting edge in vitro and in vivo research tools and approaches, including human and murine organoid cultures, genetic editing in vitro and in vivo, human iPSC models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to treat nervous system disorders and diseases. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field.
Table of Contents
1. Stem Cell-based Organoid Culture System2. Applying Innovative Genome Editing Technologies in Stem Cell Engineering, and Neurological Disorders and Diseases
3. Role of Genetically Engineered Animal Models in Investigating Neurogenic Diseases and Disorders
4. Preclinical and Clinical Applications of Stem Cell Transplantation Therapy in Neurological Disorders and Diseases
5. Advances in Stem Cell-based Therapy of Neurdegenerative Diseases
6. Derivation and Application of Haploid Neural Stem Cells in CNS Disorders and Diseases
7. Mesenchymal Stem Cell Related Therapies for Neurological Diseases and Disorders
8. The Gold Standard iPSCs and iPSC-derived Neural Cells in Modeling Neurological Diseases
9. Conclusion and Future Direction