The global orthopedic biomaterials device market was valued at $7.3 billion in 2024 and is expected to grow at a CAGR of 4.0%, reaching $9.6 billion by 2031.
This market includes multiple key segments:
- Bone Graft Substitute Market (Allograft, Demineralized Bone Matrix (DBM), and Synthetic Bone Grafts)
- Orthopedic Growth Factor Market
- Orthopedic Cell Therapy Market (Bone Marrow Aspirate Concentrate, Platelet-Rich Plasma)
- Hyaluronic Acid (HA) Viscosupplementation Market (Single-, Two-, Three-, and Five-Injection Cycles)
- Orthopedic Cartilage Repair Market (Osteochondral Allograft, Meniscal Allograft, Autologous Chondrocyte Implantation, and Osteochondral Autografts)
Market Insights & Data Coverage
- Unit Sales & Average Selling Prices
- Market Size & Growth Trends
- Procedure Numbers
- Market Drivers & Limiters
- Market Forecasts Until 2031
- Historical Data (2021-2023)
- Competitive Landscape, Mergers & Acquisitions
- Company Profiles & Product Portfolios
Market Trends
Aging Population Driving Market Growth:
- The global population aged 60+ surpassed 1 billion in 2020 and is projected to reach 2.1 billion by 2050.
- This demographic shift is expected to increase the demand for bone grafts and orthopedic biomaterials, especially for spinal fusion procedures due to age-related osteoarthritis and degenerative disc disease.
Growing Incidence of Osteoarthritis & Degenerative Conditions:
- Higher rates of age-related diseases and rising obesity levels will drive demand for orthopedic biomaterials and restorative procedures.
- Increased spinal fusion procedures will significantly boost the market for bone graft substitutes.
Advancements in Cell Therapy & Cartilage Repair:
- Innovative therapies like platelet-rich plasma and bone marrow aspirate concentrates are expanding in regenerative medicine.
- New cartilage repair techniques are improving patient outcomes and reducing the need for total joint replacements.
Market Share Insights
Top Competitors in the Global Orthopedic Biomaterials Market (2024):1 Medtronic
- Market leader in orthopedic biomaterials, particularly bone graft substitutes and orthopedic growth factors.
- The INFUSE™ product line is a dominant player in the orthopedic growth factor market.
- Second-largest market share, strong presence in bone graft substitutes and HA viscosupplementation.
- Distributes leading HA products MONOVISC® and ORTHOVISC®, manufactured by Anika Therapeutics.
3 Fidia
- Specializes in the HA viscosupplementation market with a five-injection product (HYALGAN®) and the first-ever two-injection product (Hymovis®) in the U.S.
- TRILURON® - A pre-filled HA sodium salt product for knee osteoarthritis treatment.
- The two-injection segment is experiencing rapid growth as lower-injection treatment trends gain traction.
Market Segmentation Summary
- Bone Graft Substitute Market
- Material Type: Allograft, Demineralized Bone Matrix, Synthetic Substitutes
- Orthopedic Growth Factor Market
- Indication Type: Cervical Disc Degeneration, Tibial Fracture, Spine, Ankle & Hindfoot Fusions
- Orthopedic Cell Therapy Market
- Material Type: Platelet-Rich Plasma, Bone Marrow Aspirate Concentrates
- Hyaluronic Acid (HA) Viscosupplementation Market
- Material Type: Single-Injection, Two-Injection, Three-Injection, Five-Injection Cycles
- Orthopedic Cartilage Repair Market
- Treatment Type: Osteochondral Allograft, Meniscal Allograft, Autologous Chondrocyte Implantation, Osteochondral Autografts
Global Research Scope
- Regions Covered:
- North America (U.S., Canada)
- Latin America (Brazil, Mexico, Argentina, Colombia, Chile)
- Western Europe (Germany, France, U.K., Spain, Italy)
- Central & Eastern Europe (Poland, Russia, Turkey, Hungary)
- Middle East (Saudi Arabia, UAE, Israel)
- Asia Pacific (China, Japan, India, South Korea, Australia)
- Africa (South Africa, Egypt, Nigeria, Kenya)
- Base Year: 2024
- Forecast Period: 2025-2031
- Historical Data: 2021-2023
Quantitative Coverage
- Market Size, Market Shares
- Market Forecasts, Growth Rates
- Units Sold, Average Selling Prices
- Procedure Numbers
Qualitative Coverage
- COVID-19 Impact
- Market Growth Trends & Limiters
- Competitive Analysis & SWOT for Top Competitors
- Mergers & Acquisitions
- Company Profiles & Product Portfolios
- FDA Recalls, Disruptive Technologies
- Disease Overviews
Data Sources:
- Primary Interviews with Industry Leaders
- Government Physician Data & Regulatory Data
- Hospital Private Data
- Import & Export Data
- Internal Database
Table of Contents
Executive SummaryAbbreviations
Global Orthopedic Biomaterials Device Market Overview
Eesearch methodology
Product Assessment
Global Orthopedic Biomaterials Device Market Overview
Orthopedic Bone Graft Substitute Market
Orthopedic Growth Factor Market
Orthopedic Cell Therapy Market
Hyaluronic Acid Viscosupplementation Market
Orthopedic Cartilage Repair Market
List of Charts
List of Figures
Companies Mentioned (Partial List)
A selection of companies mentioned in this report includes, but is not limited to:
- AbbVie
- LCA Pharma
- Acumed
- LifeLink Tissue Bank
- AlloSource
- LifeNet Health
- Alphatec Spine
- Meda Pharma
- Anika Therapeutics
- Medtronic
- Arthrex
- MTF
- B. Braun Melsungen
- Novabone
- Baxter
- Nuo Therapeutics
- Berkeley Advanced Biomaterials
- Octane Medical
- Biocell
- Orthocell Ltd.
- Biocomposites
- OrthogenRx
- Biogennix
- Orthofix
- Bioiberica
- Osteogenics
- Biomatlante
- OsteoMed
- Biotissue Technologies
- Paragon 28
- Bioventus
- Plasmaconcept
- Bonalive
- PromoCell
- Celling Biosciences
- Rebone Biomaterials
- Cerapedics
- Recordati
- Cingal
- Regenexx
- Croma-Pharma
- Regenity Biosciences
- CO.DON GmbH
- RTI Surgical
- CONMED
- Sanofi
- Curasan
- Sartorius CellGenix GmbH
- DCI Donor Services
- Seikagaku
- DePuy Synthes
- Smith & Nephew
- Documedica
- Solvita
- Elutia Inc.
- Spinal Elements
- Exactech
- Stella Pharmaceuticals
- Ferring Pharmaceuticals
- Stryker
- Fidia
- Takara Bio
- Finceramica
- Tedec-Meiji
- Geistlich
- Terumo
- Globus Medical/NuVasive
- Teva Pharmaceutical
- Hanmi Pharmaceutical
- ThermoGenesis
- Healiva
- TRB Chemedica
- IBSA Pharma
- Viatris
- Integra LifeSciences
- Vericel
- Isto Biologics
- Vivex
- Kolon Tissuegene
- Xtant Medical
- Kuros
- Zimmer Biomet