Bone Grafts and Substitutes

Newsletter
75 Pages
November 2024
Region: Global
Citeline
ID: 5642897

This analysis includes a discussion of products, current/forecast markets, competitors, and opportunities in the global market for bone grafts and substitutes. Product segments covered by this report include allografts and synthetic bone substitutes, growth factors, and cellular bone matrices. Geographic segments covered include the US, five major European markets (France, Germany, Italy, Spain, and the UK), Japan, and the Rest of World. The forecast range for this report is 2019-25.

The combined global market for bone grafts and substitutes totaled approximately $1.9bn in 2020. Although sales were negatively impacted by the COVID-19 pandemic, the market rebounded in 2021 and is expected to continue to increase in value over the forecast period, returning to more normal levels of growth between 2022 and 2025.

Key drivers of the bone grafts market include the aging of the population and the global burden of musculoskeletal disease, along with rising procedure volumes for spinal fusion and joint replacement surgeries. Market limiters include the high price of premium products such as growth factors and cellular bone matrices, as well as a hesitance in certain countries to use human-based allograft tissue for bone grafting.

Also included in this report:

a clinical overview of bone grafting and its current applications
spinal fusion procedure volume forecasts by country/region
osteoarthritis prevalence forecasts by country/region

Executive Summary

i. Global market

a. Selected market drivers and limiters
b. Market leaders

ii. Methodology

iii. Bibliography

Exhibit ES-1: Bone grafts and substitutes, global market forecast ($m), by product segment, 2019-25
Exhibit ES-2: Bone grafts and substitutes market, share by country/region, 2020

1. Clinical Overview

1.1 Spinal fusion
1.2 Osteoarthritis
1.3 Bibliography

Exhibit 1-1: Spinal fusion procedure volumes forecast, by country/region, 2018-25
Exhibit 1-2: Global osteoarthritis prevalence (knee or hip) forecast, by region, 2020-25

2. Allografts and Bone Graft Substitutes Market

2.1 Bone graft materials
2.2 Allograft US FDA regulations
2.3 Bone allografts and machined bone
2.4 Demineralized bone matrix
2.5 Synthetic grafts
2.6 Market analysis
2.7 Global competitive analysis
2.8 Bibliography

Exhibit 2-1: General categories of bone grafts
Exhibit 2-2: Clinical applications for bone grafts
Exhibit 2-3: Clinical applications for orthopedic allografts and synthetic grafts, by type of graft
Exhibit 2-4: Selected structural bone allografts
Exhibit 2-5: Prices of selected allografts (chips, crushed, and cubed)
Exhibit 2-6: Selected demineralized bone matrix products
Exhibit 2-7: Prices of Medtronic’s Grafton DBM gel and putty
Exhibit 2-8: Selected synthetic bone grafts
Exhibit 2-9: Prices of Medtronic’s Mastergraft synthetic bone graft
Exhibit: Global bone allograft products market, share by country/region, 2020
Exhibit: Bone allografts market, share by tissue type, 2020
Exhibit: Global bone allograft product sales by country/region, market forecast ($m), 2019-25
Exhibit: Global bone allografts and synthetic bone graft substitutes market, share by supplier, 2020

3. Market for Bone Growth Factor Grafts

3.1 Bone morphogenetic proteins
3.2 Other growth factors
3.3 Discontinued product
3.4 Emerging products
3.5 Market analysis
3.6 Competitive analysis
3.7 Bibliography

Exhibit 3-1: The Infuse Bone Graft
Exhibit 3-2: Prices of Infuse bone morphogenetic protein
Exhibit 3-3: Selected bone growth factor-based products
Exhibit 3-4: OsteoAMP putty
Exhibit 3-5: the i-Factor bone graft
Exhibit 3-6: Augment bone graft
Exhibit 3-7: Growth factor bone graft sales, market forecast, by country/region ($m), 2019-25
Exhibit 3-8: Global growth factor bone grafts market, share by country/region, 2020
Exhibit 3-9: Growth factor bone grafts, market forecast, by product line ($m), 2019-25
Exhibit: Global growth factor bone grafts market, share by supplier, 2020
Exhibit: Medtronic net sales ($m), by product category and geography, FY2020-21

4. Cellular Bone Matrices Market

4.1 CBM Products
4.2 Market analysis
4.3 Competitive analysis
4.4 Bibliography

Exhibit 4-1: Selected cellular bone matrix products
Exhibit 4-2: Prices of selected cellular bone matrix products
Exhibit 4-3: Global cellular bone matrix product sales by country/region, combined market forecast ($m), 2019-25
Exhibit 4-4: Global cellular bone matrix products market, share by country/region, 2020
Exhibit 4-5: Global cellular bone matrix products market, share by supplier, 2020

APPENDIX: COMPANY LISTING

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Table of Contents

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