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Camptothecin is a pharmaceutical intermediate used in the production of cancer drugs. It is a natural alkaloid derived from the bark and stems of the Camptotheca acuminata tree, native to China. Camptothecin has been used in traditional Chinese medicine for centuries, and is now used in the production of several chemotherapy drugs. It is known for its ability to inhibit the enzyme topoisomerase I, which is essential for DNA replication and transcription.
Camptothecin is used in the production of several cancer drugs, including irinotecan, topotecan, and exatecan. These drugs are used to treat a variety of cancers, including colorectal, ovarian, and lung cancer. Camptothecin is also used in the production of other drugs, such as the antifungal drug miltefosine.
The Camptothecin market is highly competitive, with many companies offering a variety of products. Some of the major players in the market include Sigma-Aldrich, Merck KGaA, Alfa Aesar, and TCI Chemicals. Other companies in the market include Acros Organics, BOC Sciences, and Shanghai Yuanye Bio-Technology. Show Less Read more