Results for tag: "Farnesyltransferase Inhibitors"

Farnesyltransferase inhibitors (FTIs) are a class of oncology drugs used to treat cancer. FTIs work by blocking the farnesyltransferase enzyme, which is responsible for the post-translational modification of proteins. This modification is necessary for the proteins to be able to interact with the cell membrane, and blocking it can prevent the growth and spread of cancer cells. FTIs are used to treat a variety of cancers, including melanoma, breast cancer, and non-small cell lung cancer. FTIs are generally administered orally or intravenously, and can be used in combination with other cancer treatments such as chemotherapy and radiation therapy. Side effects of FTIs can include nausea, vomiting, diarrhea, and fatigue. Companies in the FTI market include Novartis, Merck, and Pfizer. Show Less Read more