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Firdapse is a drug used to treat musculoskeletal disorders, such as Lambert-Eaton myasthenic syndrome (LEMS). It is a brand name for amifampridine, a potassium channel blocker that increases the release of acetylcholine, a neurotransmitter that helps muscles contract. Firdapse is the only approved drug for the treatment of LEMS in the United States and Europe. It is also used off-label to treat other neuromuscular disorders, such as congenital myasthenic syndromes and myasthenia gravis.
Firdapse is marketed by Catalyst Pharmaceuticals, a specialty pharmaceutical company based in the United States. The drug is available in tablet form and is administered orally. It is also available as an intravenous injection for patients who cannot take the oral form.
The Firdapse market is highly competitive, with several companies offering similar drugs for the treatment of musculoskeletal disorders. These include Biogen, Novartis, Teva Pharmaceuticals, and Mylan. Other companies in the market include Alexion Pharmaceuticals, GlaxoSmithKline, and Merck & Co. Show Less Read more