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Fluorescent in situ hybridization (FISH) is a molecular cytogenetic technique that uses fluorescent probes that bind to specific parts of the chromosome to highlight the presence or absence of DNA sequences. Within the context of molecular diagnostics, FISH plays a crucial role in identifying chromosomal abnormalities, gene mutations, and gene expressions, particularly in the fields of cancer diagnosis, genetic diseases, and personalized medicine. The technique provides clinicians with detailed insights into the genetic alterations at the cellular level, allowing for accurate diagnosis, prognosis, and monitoring of disease. Furthermore, it aids in the determination of specific therapeutic approaches based on the genetic profile of a disease. The FISH market is comprised of a variety of platforms and reagents tailored to diagnostic laboratory needs, including manual and automated systems, designed to streamline workflow and enhance the precision of results.
Several companies are prominent in the FISH market, each offering unique technologies and products for molecular diagnostics. Among these, Abbott Laboratories is known for providing automated FISH platforms. Agilent Technologies offers a range of FISH probes and kits. Thermo Fisher Scientific brings to the market molecular diagnostic solutions that include FISH assays and reagents. Leica Biosystems specializes in providing comprehensive microscopy solutions that incorporate FISH. Lastly, Bio-Techne Corporation delivers a suite of molecular diagnostic tools including FISH probes. These companies, along with others in the field, continuously innovate and contribute to the advancement of molecular diagnostics through the application of FISH techniques. Show Less Read more