Results for tag: "High Mobility Group Protein B1"

High Mobility Group Protein B1 (HMGB1) is a protein found in the nucleus of cells that plays a role in the regulation of gene expression. In oncology, HMGB1 has been studied as a potential therapeutic target for cancer. It has been found to be involved in the progression of several types of cancer, including breast, lung, and colorectal cancer. HMGB1 has been shown to be involved in the regulation of tumor growth, metastasis, and angiogenesis. In addition, HMGB1 has been found to be involved in the regulation of the immune response to cancer, and has been studied as a potential biomarker for cancer diagnosis and prognosis. Several companies are involved in the development of HMGB1-targeted therapies for oncology. These include AstraZeneca, Merck, Pfizer, and Novartis. Additionally, several biotechnology companies are developing HMGB1-targeted therapies, such as ImmunoCellular Therapeutics, OncoImmune, and ImmunoVaccine. Show Less Read more