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Neprilysin (also known as neutral endopeptidase, NEP, CD10, and EC 3.4.24.11) is an enzyme that is involved in the breakdown of peptides and proteins. It is found in the kidney, brain, and other tissues, and is involved in the metabolism of a variety of peptides, including endorphins, enkephalins, and bradykinin. Neprilysin is also involved in the regulation of blood pressure, and has been linked to the development of Alzheimer's disease.
Neprilysin is a key target for drug development, as it has been linked to a number of diseases, including hypertension, cancer, and Alzheimer's disease. Pharmaceutical companies are actively researching and developing drugs that target neprilysin, in order to treat these diseases.
Some companies in the Neprilysin market include Merck, Pfizer, Novartis, AstraZeneca, and Eli Lilly. Show Less Read more