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The Neuropeptide Y Receptor (NPY-R) is a G-protein coupled receptor (GPCR) that is involved in the regulation of a variety of physiological processes in the central nervous system (CNS). It is a target for the development of drugs for the treatment of CNS disorders such as anxiety, depression, and addiction. NPY-R agonists have been shown to have anxiolytic and antidepressant effects, while antagonists have been shown to reduce drug-seeking behavior.
NPY-R is a promising target for the development of CNS drugs, and several companies are actively researching and developing drugs targeting this receptor. These include AbbVie, AstraZeneca, Eli Lilly, Merck, and Pfizer. Show Less Read more