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Zosyn is a brand of piperacillin/tazobactam, a combination of two antibiotics used to treat a variety of bacterial infections, including those of the gastrointestinal tract. It is used to treat infections caused by susceptible bacteria, including those of the urinary tract, skin, and soft tissue. Zosyn is also used to treat intra-abdominal infections, such as appendicitis, diverticulitis, and peritonitis. It is also used to treat complicated skin and skin structure infections, including those caused by methicillin-resistant Staphylococcus aureus (MRSA). Zosyn is available in both intravenous and oral formulations. The intravenous formulation is used for the treatment of serious infections, while the oral formulation is used for the treatment of mild to moderate infections. Zosyn is available in a variety of strengths and formulations, including tablets, capsules, and injections. Zosyn is manufactured by several pharmaceutical companies, including Pfizer, Merck, and Bristol-Myers Squibb. Other companies that produce Zosyn include Teva Pharmaceuticals, Mylan, and Sandoz. Show Less Read more