This second volume of Coronaviruses brings together more useful information about the prevention/vaccination, and chemotherapies for the potential treatment of coronavirus infections.
The volume includes eight chapters:
1 Broad spectrum antivirals to combat COVID-19 The reality and challenges2 COVID-19: Preventive and protective control management strategies
3 Plant-derived extracts and bioactive compounds against coronavirus progression: preventive effects, mechanistic aspects, and structures
4 Gastroenteritis: symptoms and epidemiology of SARS-CoV-2
5 The chronicles of coronavirus: A Chinese king who conquered the entire world
6 Traditional medicine as a natural remedy in ARDS & COVID-19
7 Molecular pathogenesis of human coronaviruses of the 21st century
8 COVID-19, mental health and neuropathophysiology of pain related to temporomandibular disorder.
The volume serves as a novel compilation of key data on SARS-CoV-2 and COVID-19 and represents a resource of the utmost value for all scholars studying SARS-CoV infections. It should also be of great interest to clinicians who may be facing an overwhelming number of individuals affected with COVID-19, with over 267 million global cases documented as of the first week of December 2021).
Table of Contents
Chapter 1 Broad-Spectrum Antivirals To Combat Covid-19: The Reality And Challenges
- Wafaa A. Hewedy
- Introduction
- Drugs Targeting Entry Process
- Viral Envelope Proteins
- Nelfinavir
- Arbidol
- Host Cell Proteins
- Tmprss2 Inhibitors
- Furin Inhibitors
- Drugs Targeting Viral Replication
- Ribavirin
- Remdesivir
- Sofosbuvir
- Favipiravir
- Protease Inhibitors
- Lopinavir/Ritonavir
- Jak Inhibitors
- Baricitinib
- Abl Inhibitors
- Imatinib
- Niclosamide
- Nitazoxanide
- Conclusion
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
Chapter 2 Covid19: Preventive And Protective Control Management Strategies
- Kalyani Pathak, Manash Pratim Pathak, Urvashee Gogoi, Riya Saikia And Aparoop Das
- Introduction
- Preventive And Protective Control Management Strategies Practiced In Different Levels
- Environmental Measures
- Ensure Adequate Sanitization By Standard Disinfectants
- Ensure Proper Ventilation, Temperature, And Humidity In Confined Places
- Reduction Of Close Contact In A Closed Environment
- Identification And Management Of Isolation Room For Suspected Cases
- Organizational Measures
- Engineering Controls
- Administrative Controls
- Personal Controls
- Laboratory And Testing Controls
- Personal Measures
- Ensure Proper Use Of Ppe (Personal Protective Equipment) And Disposal After Use 47 Donning Of Ppe Kit
- Doffing Of Ppe Kit
- Disposal Of Contaminated Ppe Kit
- Ensure Proper Coughing Etiquettes
- Use Of Face Masks
- Proper Handwash Procedure
- Societal Measures
- Ensure Proper Social Distancing
- Ensure Proper Quarantine And Home Isolation Norms
- Role Of Mass And Social Media In Public Health Education System
- Awareness At The Community Level
- The Need Of The Hour
- Early Diagnoses Of The Disease
- Upgradation Of The Hospital Management System
- Efficient Training For Health Care Professionals
- Appeal For A Change In Lifestyle
- Conclusion
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
Chapter 3 Plant-Derived Extracts And Bioactive Compounds Against Coronavirus Progression: Preventive Effects, Mechanistic Aspects, And Structures
- Heba A.S. El-Nashar, Ahmed E. Elissawy, Omayma A. Eldahshan And Abdel Nasser B. Singab
- Introduction
- Materials And Methods
- Results And Discussion
- Medicinal Plants With Antiviral Activity Against Coronavirus
- Plant Extracts
- Plant Essential Oils
- Natural Compounds With Antiviral Activity Against Coronavirus 70 Phenolic Compounds
- Alkaloids
- Terpenoids
- Conclusion
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
Chapter 4 Gastroenteritis: Symptoms And Epidemiology Of Sars-Cov-2 97 Aditi Nag, Sudipti Arora And Sonia Sethi
- Introduction
- Sars-Cov-2 - The Pathogen Characteristics
- Epidemiology And Transmission
- Phases Of Infection:
- Gastrointestinal Manifestations Of Covid-19
- Discussion On Wastewater Based Epidemiology Studies And Their Findings
- Detection Of Sars- Cov-2 Genomic Rna And Genes In The Wastewater
- Future Scope
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
Chapter 5 The Chronicles Of Coronavirus: A Chinese King Who Conquered The Entire World
- Sanaullah Sajid, Sajjad-Ur Rahman, Muhammad Ali, Maliha Sarfraz, Imran Abdullah And Samiullah Sajid
- Introduction
- History
- Structural Proteins
- Assembly Of Sars-Cov
- Covid-19
- Infection By Covid-19
- Transmission
- When Should A Person Be Tested?
- Care Of Critically Ill Patients
- Prevention And Control
- Treatment
- Ncov-19 Pandemic And Way Forward
- Treatments And Potential Targets Against Sars-Cov-2
- Future Perspectives And Conclusion
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
Chapter 6 Traditional Medicine As Natural Remedy In Ards & Covid-19 Through Interleukins
- Suresh Kumar Karri And Sheela Angappan
- Introduction To Covid-19
- Covid-19 - Global Challenges
- Pathology Of Ards (Acute Respiratory Distress Syndrome) Or Ali (Acute Lung Injury)
- Ards/Ali In The Context Of Covid-19
- Il17S Role In Ards/Ali
- Cytokine Release Syndrome (Crs)
- Treatment Options
- Antiviral Drugs
- Antimalarial Drugs
- Anti-Hiv Drugs
- Anti-Inflammatory Drugs
- Monoclonal Antibodies
- What Are Their Adverse Effects?
- Ongoing Clinical Studies, Their Cost, And Disadvantages
- Herbal Medicine For Covid-19
- Effects Of Traditional Indian Medicine In Covid-19
- Mechanism Of Action Of B Erecta Extract In Il17 Inhibition & Its Efficacy In Ards 147 Limitations & Prospects Of B. Erecta
- Conclusion
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
Chapter 7 Molecular Pathogenesis Of Human Coronaviruses Of 21St Century Ruma Karmakar, Satya Vadlamani, Jyoti Verma, Sakshi Kumari And Maitreyi Syamala Rajala
- Introduction
- Comparison Of All Three Human Coronaviruses
- Proteome Comparison
- Subtypes Of Human Coronaviruses
- Host Cell Receptors Used By Coronaviruses For Infection
- Molecular Pathogenesis
- Virus Infection
- Entry Into The Host
- Transmission Dynamics
- Clinical Features Of Human Coronaviruses
- Pathogenesis Of Human Coronavirus Associated Diseases
- Lung Pathology
- Multiple Organ Dysfunction
- Immune Response
- The Cytokine Storm Induced By Coronaviruses
- The Adaptive Response With Respect To The Humoral And The Cellular Immunity
- Immune Evasion Strategies
- Animal Models To Study The Molecular Pathogenesis Of Human Coronaviruses
- Mouse Models
- Non-Human Primate Models
- Conclusion
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
Chapter 8 Covid-19, Mental Health And Neuropathophysiology Of Pain Related To Temporomandibular Disorder
- Karen Dantur Batista Chaves And Maria Cristina Munerato
- Introduction
- Temporomandibular Disorder And Orofacial Pain Mechanisms
- Mechanisms Of Orofacial Pain
- Mental Health And Temporomandibular Disorder
- Covid-19
- Conclusion
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
- Subject Index
Author
- Jean-Marc Sabatier